| WBGene00001664 | SMap | S_parent | Sequence | F38E1 |
|---|
| Identity | Version | 1 |
| | Name | CGC_name | gpa-2 | Person_evidence | WBPerson625 |
| | | Sequence_name | F38E1.5 |
| | | Molecular_name | F38E1.5 |
| | | | F38E1.5.1 |
| | | | CE04523 |
| | | Other_name | CELE_F38E1.5 | Accession_evidence | NDB | BX284605 |
| | | Public_name | gpa-2 |
| | DB_info | Database | AceView | gene | 5I853 |
| | | | WormQTL | gene | WBGene00001664 |
| | | | WormFlux | gene | WBGene00001664 |
| | | | NDB | locus_tag | CELE_F38E1.5 |
| | | | Panther | gene | CAEEL|WormBase=WBGene00001664|UniProtKB=P22454 |
| | | | | family | PTHR10218 |
| | | | NCBI | gene | 179219 |
| | | | RefSeq | protein | NM_072756.5 |
| | | | SwissProt | UniProtAcc | P22454 |
| | | | UniProt_GCRP | UniProtAcc | P22454 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | gpa |
| | Allele (41) |
| | Legacy_information | [C.elegansII] pk19, pk2, pk23, pk24, pk16. Tc1 insertion, also excision derivatives: no obvious phenotype, some reduction in dauer formation, stronger with gpa-3(O). Cloned: gpa-2:lacZ expressed in phasmid neurons, some nerve ring neurons, PVT, sphincter. [Lochrie et al. 1991; PS; NL] |
| | Strain | WBStrain00028899 |
| | | WBStrain00028902 |
| | | WBStrain00007863 |
| | RNASeq_FPKM (74) |
| | GO_annotation (25) |
| | Ortholog (45) |
| | Paralog (21) |
| | Structured_description | Concise_description | gpa-2 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases that is involved in dauer formation and chemotaxis to water-soluble odorants; it is expressed in the phasmid neurons PHA and PHB, three pharyngeal neurons, one interneuron, three pairs of head neurons, and the anal sphincter muscle. | Curator_confirmed | WBPerson48 |
| | | | | | WBPerson567 |
| | | | | Date_last_updated | 17 Jun 2004 00:00:00 |
| | | Automated_description | Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Involved in several processes, including defense response to Gram-negative bacterium; olfactory learning; and positive regulation of gene expression. Located in axon; neuronal cell body; and non-motile cilium. Expressed in anal sphincter muscle; ganglia; and pharyngeal cell. | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | F38E1.5 |
| | Corresponding_transcript | F38E1.5.1 |
| | Associated_feature | WBsf1000639 |
| | | WBsf1000640 |
| | | WBsf1020020 |
| | | WBsf232099 |
| Experimental_info | RNAi_result | WBRNAi00103344 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00046709 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103347 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00014559 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00014563 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00046710 | Inferred_automatically | RNAi_primary |
| | Expr_pattern | Expr538 |
| | | Expr539 |
| | | Expr3065 |
| | | Expr1023128 |
| | | Expr1150590 |
| | | Expr2012191 |
| | | Expr2030427 |
| | | Marker43 |
| | Drives_construct (6) |
| | Construct_product | WBCnstr00001699 |
| | | WBCnstr00004642 |
| | | WBCnstr00012427 |
| | | WBCnstr00012428 |
| | | WBCnstr00036791 |
| | Antibody | WBAntibody00000769 |
| | Microarray_results (20) |
| | Expression_cluster | WBPaper00032528:L3_depleted |
| | | WBPaper00036375:enriched_in_PVD_OLL |
| | | WBPaper00037950:A-class-motor-neurons_L2-larva_expressed |
| | | WBPaper00037950:A-class-motor-neurons_larva_enriched |
| | | WBPaper00037950:A-class-motor-neurons_larva_SelectivelyEnriched |
| | | WBPaper00037950:all-neurons_CoreEnriched |
| | | WBPaper00037950:all-neurons_embryo_enriched |
| | | WBPaper00037950:all-neurons_embryo_SelectivelyEnriched |
| | | WBPaper00037950:all-neurons_L1-larva_expressed |
| | | WBPaper00037950:all-neurons_L2-larva_expressed |
| | | WBPaper00037950:all-neurons_larva_enriched |
| | | WBPaper00037950:all-neurons_larva_SelectivelyEnriched |
| | | WBPaper00037950:BAG-neuron_blastula-embryo_expressed |
| | | WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed |
| | | WBPaper00037950:excretory-cell_L2-larva_expressed |
| | | WBPaper00037950:GABAergic-motor-neurons_embryo_enriched |
| | | WBPaper00037950:GABAergic-motor-neurons_embryo_SelectivelyEnriched |
| | | WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed |
| | | WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed |
| | | WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed |
| | | WBPaper00037950:glr-1(+)-neurons_larva_enriched |
| | | WBPaper00037950:glr-1(+)-neurons_larva_SelectivelyEnriched |
| | | WBPaper00038438:Harposporium_24hr_downregulated_RNAseq |
| | | WBPaper00042194:nhr-114(RNAi)_downregulated |
| | | WBPaper00044656:tatn-1(qd182)_upregulated |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00048988:neuron_enriched |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049377:MWCNT_downregulated |
| | | WBPaper00049545:jmjd-3.1(+)_upregulated |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050726:OsmoticStress_regulated_Food |
| | | WBPaper00050726:starvation_regulated_LowSalt |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult |
| | | WBPaper00050990:intestine_expressed |
| | | WBPaper00051558:aging_regulated |
| | | WBPaper00053184:sma-2(rax5)_upregulated |
| | | WBPaper00053184:sma-4(rax3)_upregulated |
| | | WBPaper00053302:stavudine_24h_regulated |
| | | WBPaper00053302:zidovudine_72h_regulated |
| | | WBPaper00053606:N2_vs_elt-2(ca15)_downregulated |
| | | WBPaper00054758:alg-1(gk204)_upregulated |
| | | WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated |
| | | WBPaper00055354:Rapamycin-Rifampicin_downregulated |
| | | WBPaper00055354:Rifampicin-Psora_downregulated |
| | | WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047) |
| | | WBPaper00056161:male_enriched_siRNA |
| | | WBPaper00056619:CEPsh_enriched |
| | | WBPaper00056826:hmc_biased |
| | | WBPaper00057041:spc-1(cas971)_downregulated |
| | | WBPaper00057041:unc-70(cas983)_downregulated |
| | | WBPaper00058598:mex-1(or286)_upregulated |
| | | WBPaper00058598:mex-3(eu149)_upregulated |
| | | WBPaper00058598:sin-3(tm1276)_downregulated |
| | | WBPaper00058598:spn-4(tm291)_upregulated |
| | | WBPaper00058948:PA14_downregulated |
| | | WBPaper00059664:srbc-48(ac23)_upregulated |
| | | WBPaper00059728:5ug_cholesterol_upregulated |
| | | WBPaper00059754:E.faecalis_OG1RF_upregulated |
| | | WBPaper00060459:bcat-1(RNAi)_upregulated |
| | | WBPaper00060661:sensory-neuron_enriched |
| | | WBPaper00060811:L1_vs_adult_upregulated_neural |
| | | WBPaper00061203:sin-3(tm1276)_upregulated |
| | | WBPaper00061274:microgravity_downregulated |
| | | WBPaper00061340:ADF |
| | | WBPaper00061340:ALN |
| | | WBPaper00061340:ASG |
| | | WBPaper00061340:ASI |
| | | WBPaper00061340:AVJ |
| | | WBPaper00061340:AVL |
| | | WBPaper00061340:I5 |
| | | WBPaper00061340:PVT |
| | | WBPaper00061340:RIC |
| | | WBPaper00061341:28C_24h_upregulated |
| | | WBPaper00061341:28C_48h_upregulated |
| | | WBPaper00061424:Diet_MYb120_upregulated |
| | | WBPaper00061527:acy-2-F35C5.11 |
| | | WBPaper00061651:PVT_enriched |
| | | WBPaper00061651:RIR_enriched |
| | | WBPaper00061902:camt-1(ok515)_regulated_RMG |
| | | WBPaper00061995:mter-4(syb3662syb3403)_downregulated |
| | | WBPaper00062095:unc-4(e120)_upregulated_VA-neuron |
| | | WBPaper00062103:neuron_enriched |
| | | WBPaper00062159:hda-2(ok1479)_upregulated |
| | | WBPaper00062325:muscle_depleted_coding-RNA |
| | | WBPaper00062520:qui-1(db104)_upregulated |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00065749:Heat-Shock_downregulated_N2 |
| | | WBPaper00065841:48_0 |
| | | WBPaper00065841:63_0 |
| | | WBPaper00065841:68_0 |
| | | WBPaper00065841:92_0 |
| | | WBPaper00065841:105_0 |
| | | WBPaper00065841:109_0 |
| | | WBPaper00065841:118_0 |
| | | WBPaper00065841:135_0 |
| | | WBPaper00065841:138_0 |
| | | WBPaper00065841:142_0 |
| | | WBPaper00065993:glp-1(e2141)_upregulated |
| | | WBPaper00066232:ash-2(RNAi)_downregulated_WT |
| | | cgc4489_group_15 |
| | | cgc4489_group_17 |
| | | WBPaper00024671:AFD_AWB_vs_unsorted_upregulated |
| | | WBPaper00026629:L4_male_enriched |
| | | WBPaper00027758:Group_III |
| | | WBPaper00030839:Embryo_Pan_Neuronal |
| | | WBPaper00030839:Larval_Pan_Neuronal |
| | | WBPaper00031532:Larva_Pan_Neuronal_Enriched |
| | | WBPaper00034739:N2moreDR1350 |
| | | WBPaper00039866:ClassComp_daf-19_downregulated |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_48h |
| | | WBPaper00047070:N2_starvation_upregulated |
| | | WBPaper00053236:Starvation_regulated_GR1307 |
| | | WBPaper00053236:Starvation_regulated_N2 |
| | | WBPaper00053550:daf-19(m86)_downregulated_3-fold-embryo |
| | | [cgc6390]:male_soma-enriched |
| | Interaction (17) |
| | Anatomy_function | WBbtf0865 |
| | | WBbtf0866 |
| Map_info | Map | V | Position | 1.34551 | Error | 0.005648 |
| | Positive | Positive_clone | F38E1 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | | | RP#G3/2 |
| | Mapping_data | Multi_point | 4368 |
| | Pseudo_map_position |
| Reference (70) |
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission |
| Method | Gene |
