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WormBase Tree Display for Gene: WBGene00000181

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Name Class

WBGene00000181SMapS_parentSequenceF01G4
IdentityVersion1
NameCGC_nameard-1
Sequence_nameF01G4.2
Molecular_name (6)
Other_nameCELE_F01G4.2Accession_evidenceNDBBX284604
Public_nameard-1
DB_infoDatabaseAceViewgene4L897
WormQTLgeneWBGene00000181
WormFluxgeneWBGene00000181
NDBlocus_tagCELE_F01G4.2
PanthergeneCAEEL|WormBase=WBGene00000181|UniProtKB=Q19102
familyPTHR43658
NCBIgene178016
RefSeqproteinNM_001307064.3
NM_069682.8
TrEMBLUniProtAccQ19102
A0A061AD09
UniProt_GCRPUniProtAccQ19102
OMIMgene300256
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classard
Allele (29)
StrainWBStrain00049398
RNASeq_FPKM (74)
GO_annotation00000186
00000187
00000188
00000189
00000190
00000191
Contained_in_operonCEOP4412
Ortholog (44)
Paralog (38)
Structured_descriptionConcise_descriptionard-1 encodes a homolog of mammalian 3-hydroxyacyl-CoA dehydrogenase (HADH II)/amyloid-beta binding alcohol dehydrogenase (ABAD) that is predicted to be mitochondrial.Paper_evidenceWBPaper00004424
WBPaper00012828
WBPaper00013599
WBPaper00013615
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable estradiol 17-beta-dehydrogenase [NAD(P)] activity. Predicted to be involved in androgen metabolic process; estrogen metabolic process; and fatty acid metabolic process. Predicted to be located in mitochondrion. Expressed in hypodermis. Human ortholog(s) of this gene implicated in Alzheimer's disease; osteosarcoma; pheochromocytoma; and syndromic X-linked intellectual disability type 10. Is an ortholog of human HSD17B10 (hydroxysteroid 17-beta dehydrogenase 10).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4800)
DOID:3347Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4800)
DOID:0060810Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4800)
DOID:0050771Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4800)
Molecular_infoCorresponding_CDSF01G4.2a
F01G4.2b
Corresponding_transcriptF01G4.2a.1
F01G4.2b.1
Other_sequence (74)
Associated_featureWBsf997771
WBsf997772
WBsf1018176
WBsf229103
WBsf229104
Experimental_infoRNAi_resultWBRNAi00025001Inferred_automaticallyRNAi_primary
WBRNAi00027256Inferred_automaticallyRNAi_primary
WBRNAi00043779Inferred_automaticallyRNAi_primary
WBRNAi00076269Inferred_automaticallyRNAi_primary
WBRNAi00012757Inferred_automaticallyRNAi_primary
WBRNAi00102583Inferred_automaticallyRNAi_primary
WBRNAi00030558Inferred_automaticallyRNAi_primary
WBRNAi00102692Inferred_automaticallyRNAi_primary
WBRNAi00102683Inferred_automaticallyRNAi_primary
WBRNAi00102674Inferred_automaticallyRNAi_primary
Expr_patternExpr8141
Expr12157
Expr1024424
Expr1030105
Expr1147756
Expr2009389
Expr2027625
Drives_constructWBCnstr00013141
WBCnstr00020295
WBCnstr00037681
Construct_productWBCnstr00037681
Microarray_results (21)
Expression_clusterWBPaper00026640:Development_Group_I
WBPaper00032528:L3_enriched
WBPaper00033065:cyc-1(RNAi)_upregulated
WBPaper00037047:insoluble_protein
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:bodywall-muscle_L1-larva_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:coelomocytes_embryo_enriched
WBPaper00037950:coelomocytes_embryo_SelectivelyEnriched
WBPaper00037950:coelomocytes_L1-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038168:lin-15B(n744)_downregulated
WBPaper00038289:oocyte_protein
WBPaper00040965:lipid-droplet_associated_protein
WBPaper00044128:daf-2(e1370)_upregulated
WBPaper00044578:4-day_reduced-humidity_downregulated_proteomics
WBPaper00044736:flat_dev_expression
WBPaper00045521:Gender_Neutral
WBPaper00045571:germline-ablation_downregulated
WBPaper00045974:NSM_enriched_totalRNA_RNAseq
WBPaper00046217:mev-1(kn1)_upregulated
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
WBPaper00048644:germline_enriched
WBPaper00048923:Aging_regulated
WBPaper00048988:neuron_expressed
WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
WBPaper00049942:hsf-1(RNAi)_downregulated
WBPaper00050015:ifg-1(RNAi)_downregulated
WBPaper00050488:20C_vs_25C_regulated_N2_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:starvation_regulated_LowSalt
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:pharynx_expressed
WBPaper00050990:seam_expressed
WBPaper00051558:aging_regulated
WBPaper00051558:fog-2(q71)_regulated
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053302:stavudine_24h_regulated
WBPaper00053388:dauer_regulated_Cluster5
WBPaper00053615:SMO-1_target
WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
WBPaper00055354:Rifampicin-Allantoin_upregulated
WBPaper00055482:pmt-2(RNAi)_downregulated
WBPaper00055626:pry-1(mu38)_upregulated
WBPaper00055648:germline_expressed
WBPaper00055969:electromagnetic-field_upregulated
WBPaper00055971:nhl-2(ok818)_25C_downregulated
WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
WBPaper00056275:P.aeruginosa_downregulated
WBPaper00056275:P.aeruginosa_downregulated_pmk-1(km25)_dependent
WBPaper00056275:P.aeruginosa_upregulated
WBPaper00056275:P.aeruginosa_upregulated_pmk-1(km25)_dependent
WBPaper00056809:smn-1(ok355)_downregulated
WBPaper00056826:SGP_biased
WBPaper00056900:PID-3_interacting
WBPaper00057288:Cold_downregulated_transcript
WBPaper00057288:iff-1(RNAi)_downregulated_transcript
WBPaper00059254:CSR-1_interacting
WBPaper00060100:SiNP_downregulated_mRNA
WBPaper00060661:sensory-neuron_depleted
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00060909:atfs-1(cmh15)_downregulated
WBPaper00061340:Parents_of_Y_DA6_DA7_DA9
WBPaper00061340:Parent_of_g1P_I3
WBPaper00061341:28C_24h_downregulated
WBPaper00061341:28C_48h_downregulated
WBPaper00061527:atad-3-mpst-1
WBPaper00061530:nhr-49(e2144)_downregulated
WBPaper00062159:hda-2(ok1479)_downregulated
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00062554:MAGU-2_interacting
WBPaper00062669:extracellular-vesicle_protein
WBPaper00064071:NHR-49_interacting
WBPaper00064257:UNG-1_interacting
WBPaper00064716:paraquat_downregulated
WBPaper00065086:JU1400_N.ausubeli_regulated
WBPaper00065086:JU1400_N.ferruginous_regulated
WBPaper00065120:body-muscle-transcriptome
cgc4386_cluster_2_5
cgc4489_group_5
WBPaper00025141:N2_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026980:intestine_enriched
WBPaper00032165:differentially_expressed_with_age_medoid_2
WBPaper00032948:StarveUp3
WBPaper00035560:ahr-1_downregulated
WBPaper00036286:Pattern_E
WBPaper00038231:Cry5B_1.5-fold_downregulated
WBPaper00041606:CE_B.thuringiensis-DB27_regulated
WBPaper00041606:CE_S.marcescens_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
WBPaper00044535:male_downregulated
WBPaper00045263:nuo-6(qm200)_upregulated
[cgc5767]:expression_class_M
[cgc5767]:expression_class_SM
[cgc6390]:mixed_oogenesis-somatic
Interaction (60)
Map_infoMapIVPosition4.90778
PositivePositive_cloneF01G4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00026640
WBPaper00026800
WBPaper00028352
WBPaper00031915
WBPaper00038491
WBPaper00041771
WBPaper00042257
WBPaper00055090
WBPaper00062444
WBPaper00062625
RemarkThe name sad was previously used for this Short-chain Alcohol Dehydrogenase ERAB family by Carl Johnson.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene