WormBase Tree Display for Gene: WBGene00010785

WBGene00010785 SMap: S_parent: Sequence: CHROMOSOME_II
  Identity: Version: 3
    Name: CGC_name: top-2
      Sequence_name: K12D12.1
      Molecular_name: K12D12.1
        K12D12.1.1
        CE06184
      Other_name: mel-15 Person_evidence: WBPerson314
            WBPerson3517
            WBPerson205
        topo-II Paper_evidence: WBPaper00053817
        CELE_K12D12.1 Accession_evidence: NDB BX284602
      Public_name: top-2
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:51 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 20 Feb 2008 14:21:45 WBPerson2970 Name_change: CGC_name: top-2
        3 16 Jul 2015 15:08:53 WBPerson2970 Event: Acquires_merge: WBGene00003200
              Name_change: Other_name: mel-15
      Acquires_merge: WBGene00003200
    Status: Live
  Gene_info (12)
  Disease_info: Potential_model: DOID:8991 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11989)
      DOID:2154 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11989)
      DOID:0060074 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11989)
      DOID:11054 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11989)
      DOID:10283 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11989)
      DOID:11624 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11989)
  Molecular_info: Corresponding_CDS: K12D12.1
    Corresponding_transcript: K12D12.1.1
    Other_sequence (56)
    Associated_feature (11)
  Experimental_info: RNAi_result: WBRNAi00007532 Inferred_automatically: RNAi_primary
      WBRNAi00050651 Inferred_automatically: RNAi_primary
      WBRNAi00025955 Inferred_automatically: RNAi_primary
      WBRNAi00059135 Inferred_automatically: RNAi_primary
      WBRNAi00112094 Inferred_automatically: RNAi_primary
      WBRNAi00027032 Inferred_automatically: RNAi_primary
      WBRNAi00000194 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr13143
      Expr13144
      Expr15445
      Expr15446
      Expr1020706
      Expr1034722
      Expr1154366
      Expr2017458
      Expr2035597
    Drives_construct: WBCnstr00031147
    Construct_product: WBCnstr00031147
    Antibody: WBAntibody00002769
      WBAntibody00002895
    Microarray_results (23)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032425:up_in_lin-35
      WBPaper00033070:Rhine_downregulated
      WBPaper00037047:aging_accelerated_insoluble_protein
      WBPaper00037047:insoluble_protein
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00038168:lin-15B(n744)_downregulated
      WBPaper00038168:lin-35_upregulated
      WBPaper00038289:oocyte_protein
      WBPaper00043951:insoluble_protein_day16_N2
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_upregulated_Day5
      WBPaper00044746:aging_upregulated_Day10
      WBPaper00044746:aging_upregulated_HeatShock
      WBPaper00044760:germline_specific
      WBPaper00045050:csr-1(hypomorph)_downregulated
      WBPaper00045050:drh-3 (ne4253)_downregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00045729:gld-2(RNAi)_downregulated
      WBPaper00046337:monosomal_N2_vs_daf-2_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046509:lin-35(n745)_upregulated
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049498:npr-1(ur89)_regulated_6
      WBPaper00049626:UNC-75_target
      WBPaper00049920:Glucose-Diet_downregulated_N2
      WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050015:ifg-1(RNAi)_upregulated
      WBPaper00050193:cec-4(ok3124)_downregulated_L1
      WBPaper00050234:lin-28(RNAi)_upregulated
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050522:mafr-1(tm6082)_downregulated
      WBPaper00050686:glp-1(e2141)_downregulated
      WBPaper00050698:DEP-1_interacting
      WBPaper00050712:RC301_vs_DA650_4h-PA_upregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:body-wall-muscle_nucleus_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:nucleus_specific
      WBPaper00051437:Cit-SPIONs_upregulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_upregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00055013:HMG-4_interacting_protein
      WBPaper00055226:ADR-2_target_N2
      WBPaper00055334:DLC-1_interacting
      WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated
      WBPaper00055626:pry-1(mu38)_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00055827:pfd-6(gk493446)_downregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055971:nhl-2(ok818)_20C_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:flcn-1(ok975)_downregulated
      WBPaper00056997:NMAD-1_interacting
      WBPaper00057006:DietaryRestriction_downregulated
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058691:CFP-1_interacting_protein
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059471:EGL-43_interacting
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060459:bcat-1(RNAi)_downregulated
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00061007:HB101_downregulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061340:ABarpaaa_lineage
      WBPaper00061340:ADA_ADE_grandparent
      WBPaper00061340:ASE_parent
      WBPaper00061340:ASI_parent
      WBPaper00061340:ASK_parent
      WBPaper00061340:Ciliated_amphid_neuron
      WBPaper00061340:Ciliated_non_amphid_neuron
      WBPaper00061340:Excretory_cell_parent
      WBPaper00061340:I2_grandparent
      WBPaper00061340:Neuroblast_AIZ_FLP
      WBPaper00061340:Neuroblast_AIZ_FLP_RMG
      WBPaper00061340:Neuroblast_ALA_RMED
      WBPaper00061340:Neuroblast_ASE_ASJ_AUA
      WBPaper00061340:Neuroblast_ASJ_AUA
      WBPaper00061340:Neuroblast_BAG_SMDVx
      WBPaper00061340:Neuroblast_IL1_IL2
      WBPaper00061340:Neuroblast_PVC_LUA
      WBPaper00061340:OLL_parent
      WBPaper00061340:OLQ_grandparent
      WBPaper00061340:Parent_of_hyp3_ILsoDx
      WBPaper00061340:Parent_of_K_Kprime
      WBPaper00061340:Pharyngeal_neuron
      WBPaper00061340:PLM_ALN_grandparent
      WBPaper00061340:PLM_ALN_great_grandparent
      WBPaper00061340:RIC_parent
      WBPaper00061340:RID_parent
      WBPaper00061478:SUMO-conjugated_protein
      WBPaper00061527:F54E7.8-orc-5_6376
      WBPaper00061699:daf-18(ok480)_upregulated
      WBPaper00061753:csr-1(tor159)_downregulated_25C
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00062056:lin-35(n745)_upregulated
      WBPaper00062056:lin-36(we36)_upregulated
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062325:etr-1(lq61)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062456:doxycycline_downregulated_CB4856_protein
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA
      WBPaper00064055:trl-1(cas1077)_upregulated_non-starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064201:SNA-1_interacting
      WBPaper00064201:SNA-3_interacting
      WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated
      WBPaper00064315:mes-3(bn199)_downregulated_EGCs
      WBPaper00064315:mes-4(bn73)_downregulated_EGCs
      WBPaper00064403:Heat-killed-E.Coli_upregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00064871:hypoxia_upregulated_F1
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065149:lin-52(n771)_upregulated
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065373:sek-1(km4)_upregulated_Ref
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00065995:M.humicola-extract_downregulated_old-1(ok1273)
      WBPaper00066110:Doxorubicin_downregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4386_cluster_6_2
      cgc4489_group_3
      WBPaper00025032:cluster_22
      WBPaper00025099:MA_specific
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00028564:CeMM_vs_NGM_downregulated
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031060:2-deoxy-D-glucose_downregulated
      WBPaper00032165:differentially_expressed_with_age_medoid_1
      WBPaper00032948:FedUp
      WBPaper00035227:heat_shock_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00038060:SUMO-1_upregulated
      WBPaper00040426:CYE-1_CDK-2AF_upregulated
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00048637:lin-35(n745)_starvation_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00055435:AuNPs_downregulated
      WBPaper00056330:mrps-5(RNAi)_downregulated
      [cgc5767]:cluster_4
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_ET
      [cgc5767]:expression_class_ET_max(122_min)
      [cgc5767]:expression_class_E_pi(23_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc5767]:expression_class_MET
      [cgc6390]:Cluster_F
      [cgc6390]:oogenesis-enriched
    Interaction (466)
  Map_info (4)
  Reference: WBPaper00001109
    WBPaper00028457
    WBPaper00028564
    WBPaper00031437
    WBPaper00035869
    WBPaper00038491
    WBPaper00039308
    WBPaper00047270
    WBPaper00047283
    WBPaper00047864
    WBPaper00048135
    WBPaper00049828
    WBPaper00050211
    WBPaper00051471
    WBPaper00052027
    WBPaper00052287
    WBPaper00052288
    WBPaper00053291
    WBPaper00053817
    WBPaper00055090
    WBPaper00056997
    WBPaper00057762
    WBPaper00057765
    WBPaper00059358
    WBPaper00061434
    WBPaper00063099
    WBPaper00063125
    WBPaper00064349
    WBPaper00064630
    WBPaper00065789
    WBPaper00065997
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene