WormBase Tree Display for Gene: WBGene00002850

WBGene00002850 SMap: S_parent: Sequence: C16A3
  Identity: Version: 2
    Name: CGC_name: let-716 Person_evidence: WBPerson533
      Sequence_name: C16A3.3
      Molecular_name: C16A3.3
        C16A3.3.1
        CE27690
      Other_name: CELE_C16A3.3 Accession_evidence: NDB BX284603
      Public_name: let-716
    DB_info: Database: WormQTL gene WBGene00002850
        WormFlux gene WBGene00002850
        NDB locus_tag CELE_C16A3.3
        Panther gene CAEEL|WormBase=WBGene00002850|UniProtKB=Q18038
          family PTHR23270
        NCBI gene 175906
        RefSeq protein NM_065997.5
        TREEFAM TREEFAM_ID TF105697
        TrEMBL UniProtAcc Q18038
        UniProt_GCRP UniProtAcc Q18038
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:29 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 30 Jan 2008 10:06:04 WBPerson2970 Event: Acquires_merge: WBGene00015808
              Name_change: Sequence_name: C16A3.3
      Acquires_merge: WBGene00015808
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: let
    Allele (64)
    Legacy_information: [Stewart HI] homozygotes arrest at early larval stage
      [C.elegansII] s2457 : early larval lethal. OA1: s2626 (similar). [BC]
    Strain: WBStrain00000771
    RNASeq_FPKM (74)
    GO_annotation: 00060046
      00060047
      00060048
      00060049
      00060050
      00110407
      00110408
      00110409
    Contained_in_operon: CEOP3368
    Ortholog (39)
    Structured_description: Automated_description: Predicted to enable RNA binding activity. Predicted to be involved in rRNA processing. Predicted to be located in nucleolus. Predicted to be part of small-subunit processome. Is an ortholog of human PDCD11 (programmed cell death 11). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C16A3.3
    Corresponding_transcript: C16A3.3.1
    Other_sequence: Tcol_isotig16954
      BU666188.1
      JI170983.1
      Acan_isotig07515
      Tcir_isotig06480
      PTC02877_1
      Acan_isotig17402
      HBC20004_1
      SS02606
      Oden_isotig10317
      FG348269.1
      JI171870.1
      NAC00895_1
      JI215638.1
      SSC04387_1
      CR04287
      Acan_isotig13712
      PSC02876_1
      PT03579
      Dviv_isotig23218
      Tcol_isotig21072
      Hbac_isotig05675
      Oden_isotig10316
      Oden_isotig10319
      GW408887.1
      JI164143.1
      ES413688.1
      CJC14241_1
      Name_isotig03763
      Oden_isotig21664
      Oden_isotig10315
      PP01785
      Oden_isotig10318
      Hbac_isotig05066
      CRC02191_1
    Associated_feature: WBsf659070
      WBsf225096
  Experimental_info: RNAi_result (24)
    Expr_pattern: Expr1013064
      Expr1031366
      Expr1144708
      Expr2013072
      Expr2031304
    Microarray_results (19)
    Expression_cluster: WBPaper00028451:Abundant_spermatogenesis_enriched
      WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032031:DConiospora_downregulated_cDNA_12h
      WBPaper00032031:DConiospora_upregulated_cDNA_24h
      WBPaper00037950:AVA-neuron_embryo_enriched
      WBPaper00037950:AVA-neuron_embryo_SelectivelyEnriched
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00042194:nhr-114(RNAi)_upregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045314:S.aureus-induced_N2
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045521:Gender_Neutral
      WBPaper00048988:neuron_expressed
      WBPaper00049159:Microwave_upregulated_adult
      WBPaper00049920:Glucose-Diet_downregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_downregulated_N2
      WBPaper00049954:BPS_downregulated
      WBPaper00050080:rbr-2(tm3141)_downregulated
      WBPaper00050686:glp-1(e2141)_downregulated
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:intestine_enriched
      WBPaper00050990:intestine_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:body-wall-muscle_nucleus_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:nucleus_specific
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00055334:DLC-1_interacting
      WBPaper00055354:Rapamycin-Metformin_upregulated
      WBPaper00055482:pmt-2(RNAi)_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00055969:electromagnetic-field_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058691:cfp-1(tm6369)_downregulated
      WBPaper00058691:set-2(bn129)_downregulated
      WBPaper00059254:CSR-1_interacting
      WBPaper00059254:PRG-1_interacting
      WBPaper00059471:EGL-43_interacting
      WBPaper00059605:MUT-16_interacting
      WBPaper00060445:ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061340:Body_wall_muscle
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
      WBPaper00061479:HDA-1_interacting_protein
      WBPaper00061527:ZK792.5-T26G10.1
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00064055:trl-1(cas1077)_upregulated_non-starved
      WBPaper00064055:trl-1(cas1077)_upregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064080:let-7_miRNA_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064315:mes-3(bn199)_downregulated_EGCs
      WBPaper00064315:mes-4(bn73)_downregulated_EGCs
      WBPaper00064716:paraquat_upregulated
      WBPaper00064939:vit-5(RNAi)_upregulated
      WBPaper00065158:25C_vs_15C_downregulated_AFD
      WBPaper00065225:nhr-42(tm1375)_upregulated_S.aureus-infected
      WBPaper00065258:anchor-cell_depleted
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065623:2
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4489_group_1
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00025032:cluster_36
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00032165:differentially_expressed_with_age_medoid_5
      WBPaper00035905:FBF-1_Associated
      WBPaper00036123:Atrazine_regulated
      WBPaper00036286:Pattern_E
      WBPaper00036429:glp-1(oz112)_upregulated
      WBPaper00040823:alg-1(gk214)_downregulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(83_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc6390]:intrinsic
    SAGE_tag (21)
    Interaction (353)
  Map_info: Map: III Position: -1.31646 Error: 0.00703
    Well_ordered
    Positive: Inside_rearr: sDf127
        sDf125
        sDp3
      Positive_clone: C16A3 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 3328
      Pos_neg_data: 8680
        8695
        8708
        8711
        8753
        8770
        9198
  Reference: WBPaper00002901
    WBPaper00003304
    WBPaper00015389
    WBPaper00023496
    WBPaper00028451
    WBPaper00031176
    WBPaper00038491
    WBPaper00055090
  Remark: Rescue for s2457 was to fertile adult and for s2626 to sterile adult from early larval arrest stages.
  Method: Gene