WormBase Tree Display for Gene: WBGene00000036
expand all nodes | collapse all nodes | view schema
| WBGene00000036 | SMap | S_parent | Sequence | CHROMOSOME_I | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | ace-2 | Person_evidence | WBPerson1417 | |||||
| WBPerson36909 | |||||||||
| WBPerson7188 | |||||||||
| Sequence_name | Y44E3A.2 | ||||||||
| Molecular_name | Y44E3A.2 | ||||||||
| Y44E3A.2.1 | |||||||||
| CE28363 | |||||||||
| Y44E3A.2.2 | |||||||||
| Other_name | cest-20 | ||||||||
| CELE_Y44E3A.2 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | ace-2 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:19 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 02 Mar 2018 11:09:16 | WBPerson4025 | Event | Split_into | WBGene00303088 | ||||
| 3 | 20 May 2019 14:10:26 | WBPerson1983 | Name_change | CGC_name | ace-2 | ||||
| Other_name | cest-20 | ||||||||
| Split_into | WBGene00303088 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ace | ||||||||
| Reference_allele | WBVar00145393 | ||||||||
| Allele (145) | |||||||||
| Legacy_information | g72 : class B acetylcholinesterase reduced 98%; no behavioral phenotype alone (see ace-1). ES1 ME3. NA12 (g73 etc.). | ||||||||
| [C.elegansII] g72 : class B acetylcholinesterase reduced 98%; no behavioral phenotype alone (see ace-1). ES1 ME3. OA11: g73 etc. [Culotti et al. 1981] | |||||||||
| Strain | WBStrain00022541 | ||||||||
| WBStrain00024339 | |||||||||
| WBStrain00032627 | |||||||||
| WBStrain00040622 | |||||||||
| WBStrain00007852 | |||||||||
| WBStrain00007853 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (23) | |||||||||
| Ortholog (57) | |||||||||
| Paralog (41) | |||||||||
| Structured_description | Concise_description | An acetylcholineesterase involved in the termination of cholinergic nerve transmission; it is predominantly expressed in motoneurons. | Paper_evidence | WBPaper00004932 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables acetylcholinesterase activity and protein homodimerization activity. Involved in acetylcholine catabolic process; cholinergic synaptic transmission; and regulation of locomotion. Predicted to be located in extracellular space and plasma membrane. Expressed in several structures, including command interneuron; neurons; pm5; somatic nervous system; and tail hypodermis. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Huntington's disease; artery disease (multiple); and diabetes mellitus (multiple). Is an ortholog of human BCHE (butyrylcholinesterase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (15) | ||||||||
| Molecular_info | Corresponding_CDS | Y44E3A.2 | |||||||
| Corresponding_CDS_history | Y44E3A.2a:wp264 | ||||||||
| Y44E3A.2b:wp264 | |||||||||
| Corresponding_transcript | Y44E3A.2.1 | ||||||||
| Y44E3A.2.2 | |||||||||
| Other_sequence (77) | |||||||||
| Associated_feature (13) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00027756 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00056556 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr2633 | ||||||||
| Expr12715 | |||||||||
| Expr1017666 | |||||||||
| Expr1030016 | |||||||||
| Expr1160030 | |||||||||
| Expr2009143 | |||||||||
| Expr2027380 | |||||||||
| Drives_construct | WBCnstr00009876 | ||||||||
| WBCnstr00009898 | |||||||||
| WBCnstr00009899 | |||||||||
| WBCnstr00009900 | |||||||||
| WBCnstr00009901 | |||||||||
| WBCnstr00009902 | |||||||||
| WBCnstr00009903 | |||||||||
| WBCnstr00009904 | |||||||||
| WBCnstr00009905 | |||||||||
| WBCnstr00009906 | |||||||||
| WBCnstr00009907 | |||||||||
| WBCnstr00009908 | |||||||||
| WBCnstr00009909 | |||||||||
| WBCnstr00009910 | |||||||||
| WBCnstr00009911 | |||||||||
| WBCnstr00009912 | |||||||||
| WBCnstr00010878 | |||||||||
| WBCnstr00022777 | |||||||||
| WBCnstr00038789 | |||||||||
| Construct_product | WBCnstr00009876 | ||||||||
| WBCnstr00022777 | |||||||||
| Regulate_expr_cluster | WBPaper00044452:ace_1_ace-2_downregulated | ||||||||
| WBPaper00044452:ace_1_ace-2_upregulated | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (108) | |||||||||
| Interaction (41) | |||||||||
| Map_info | Map | I | Position | -3.85604 | Error | 0.023989 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | Y44E3A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | 2_point | 1019 | |||||||
| 3681 | |||||||||
| Multi_point | 815 | ||||||||
| 3202 | |||||||||
| 3204 | |||||||||
| 4026 | |||||||||
| 5317 | |||||||||
| Pos_neg_data | 8067 | ||||||||
| 8532 | |||||||||
| Reference (85) | |||||||||
| Method | Gene |
