WormBase Tree Display for Gene: WBGene00000534
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WBGene00000534 | SMap | S_parent | Sequence | R01B10 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | cpi | ||||||
Allele (30) | |||||||
Strain | WBStrain00031908 | ||||||
WBStrain00054915 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (20) | |||||||
Ortholog (48) | |||||||
Paralog | WBGene00000535 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
WBGene00016523 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00023486 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
Structured_description | Automated_description | Enables cysteine-type endopeptidase inhibitor activity. Involved in positive regulation of vitellogenesis; regulation of oocyte development; and regulation of protein processing. Located in extracellular space and yolk granule. Expressed in hypodermis; pharyngeal gland cell; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; CST3-related cerebral amyloid angiopathy; artery disease (multiple); and autoimmune disease of the nervous system (multiple). Is an ortholog of several human genes including CST1 (cystatin SN); CST2 (cystatin SA); and CST3 (cystatin C). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model (17) | ||||||
Molecular_info | Corresponding_CDS | R01B10.1a | |||||
Corresponding_transcript | R01B10.1b | ||||||
R01B10.1a.1 | |||||||
Other_sequence (85) | |||||||
Associated_feature | WBsf028073 | ||||||
WBsf646851 | |||||||
WBsf655095 | |||||||
WBsf661303 | |||||||
WBsf661304 | |||||||
WBsf661305 | |||||||
WBsf1000163 | |||||||
WBsf231832 | |||||||
Experimental_info | RNAi_result (11) | ||||||
Expr_pattern | Expr3711 | ||||||
Expr7868 | |||||||
Expr7869 | |||||||
Expr1020802 | |||||||
Expr1030320 | |||||||
Expr1154795 | |||||||
Expr2010490 | |||||||
Expr2028730 | |||||||
Drives_construct | WBCnstr00012962 | ||||||
Construct_product | WBCnstr00012962 | ||||||
Antibody | WBAntibody00001122 | ||||||
Microarray_results (31) | |||||||
Expression_cluster (137) | |||||||
Interaction | WBInteraction000143932 | ||||||
WBInteraction000306622 | |||||||
WBInteraction000552020 | |||||||
WBInteraction000577508 | |||||||
Map_info | Map | V | Position | -0.400385 | Error | 0.008156 | |
Positive | Positive_clone | R01B10 | Inferred_automatically | From CDS info | |||
From sequence, transcript, pseudogene data | |||||||
Mapping_data | Multi_point | 4964 | |||||
4240 | |||||||
Pseudo_map_position | |||||||
Reference (12) | |||||||
Remark | Sequence connection from [Hashmi S, Lustigan S], [krb 020711] | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |