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WormBase Tree Display for Gene: WBGene00004277

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WBGene00004277	SMap	S_parent	Sequence	Y92C3B
	Identity	Version	1
		Name	CGC_name	rab-18	Person_evidence	WBPerson451
			Sequence_name	Y92C3B.3
			Molecular_name	Y92C3B.3a
				Y92C3B.3a.1
				CE34438
				Y92C3B.3b
				CE27340
				Y92C3B.3a.2
				Y92C3B.3b.1
				Y92C3B.3b.2
			Other_name	pra-1	Accession_evidence	EMBL	U23938
				CELE_Y92C3B.3	Accession_evidence	NDB	BX284603
			Public_name	rab-18
		DB_info	Database	AceView	gene	3C168
				WormQTL	gene	WBGene00004277
				WormFlux	gene	WBGene00004277
				NDB	locus_tag	CELE_Y92C3B.3
				Panther	gene	CAEEL\|WormBase=WBGene00004277\|UniProtKB=Q8MXS1
					family	PTHR24073
				NCBI	gene	175272
				RefSeq	protein	NM_171861.6
						NM_171081.7
				SwissProt	UniProtAcc	Q8MXS1
				TREEFAM	TREEFAM_ID	TF313448
				UniProt_GCRP	UniProtAcc	Q8MXS1
				OMIM	gene	602207
		Species	Caenorhabditis elegans
		History	Version_change	1	07 Apr 2004 11:29:34	WBPerson1971	Event	Imported	Initial conversion from geneace
		Status	Live
	Gene_info	Biotype	SO:0001217
		Gene_class	rab
		Allele (79)
		Strain	WBStrain00032332
		RNASeq_FPKM (74)
		GO_annotation	00084671
			00084672
			00084673
			00084674
			00084675
			00084676
			00084677
			00084678
			00112596
			00112597
		Contained_in_operon	CEOP3052
		Ortholog	WBGene00035481	Caenorhabditis briggsae	From_analysis	Hillier-set
						OrthoMCL
						OMA
						Inparanoid_8
						WormBase-Compara
			WBGene00065405	Caenorhabditis remanei	From_analysis	OMA
						TreeFam
						Inparanoid_8
						WormBase-Compara
			WBGene00142155	Caenorhabditis brenneri	From_analysis	OMA
						TreeFam
						Inparanoid_8
						WormBase-Compara
			WBGene00125135	Caenorhabditis japonica	From_analysis	OMA
						TreeFam
						Inparanoid_8
						WormBase-Compara
			WBGene00114928	Pristionchus pacificus	From_analysis	Inparanoid_8
			WBGene00226338	Brugia malayi	From_analysis	WormBase-Compara
			WBGene00227442	Brugia malayi	From_analysis	WormBase-Compara
			WBGene00231176	Brugia malayi	From_analysis	WormBase-Compara
			CBOVI.g5309	Caenorhabditis bovis	From_analysis	WormBase-Compara
			CSP21.g249	Caenorhabditis parvicauda	From_analysis	WormBase-Compara
			CSP26.g3449	Caenorhabditis zanzibari	From_analysis	WormBase-Compara
			CSP28.g12890	Caenorhabditis panamensis	From_analysis	WormBase-Compara
			CSP29.g10508	Caenorhabditis becei	From_analysis	WormBase-Compara
			CSP31.g10961	Caenorhabditis uteleia	From_analysis	WormBase-Compara
			CSP32.g10590	Caenorhabditis sulstoni	From_analysis	WormBase-Compara
			CSP38.g7235	Caenorhabditis quiockensis	From_analysis	WormBase-Compara
			CSP40.g5289	Caenorhabditis tribulationis	From_analysis	WormBase-Compara
			Cang_2012_03_13_00030.g1737	Caenorhabditis angaria	From_analysis	WormBase-Compara
			Cni-rab-18	Caenorhabditis nigoni	From_analysis	WormBase-Compara
			Csp11.Scaffold630.g20298	Caenorhabditis tropicalis	From_analysis	WormBase-Compara
			Csp5_scaffold_01414.g20774	Caenorhabditis sinica	From_analysis	WormBase-Compara
			FL83_16780	Caenorhabditis latens	From_analysis	WormBase-Compara
			GCK72_011740	Caenorhabditis remanei	From_analysis	WormBase-Compara
			OTIPU.nOt.2.0.1.g06303	Oscheius tipulae	From_analysis	WormBase-Compara
			OTIPU.nOt.2.0.1.g11685	Oscheius tipulae	From_analysis	WormBase-Compara
			Pan_g16041	Panagrellus redivivus	From_analysis	WormBase-Compara
			Pan_g22952	Panagrellus redivivus	From_analysis	WormBase-Compara
			Pan_g5537	Panagrellus redivivus	From_analysis	WormBase-Compara
			Sp34_30317100	Caenorhabditis inopinata	From_analysis	WormBase-Compara
			chrIII_pilon.g6882	Caenorhabditis elegans	From_analysis	WormBase-Compara
			WBGene00239480	Onchocerca volvulus	From_analysis	WormBase-Compara
			WBGene00242170	Onchocerca volvulus	From_analysis	WormBase-Compara
			WBGene00244944	Onchocerca volvulus	From_analysis	WormBase-Compara
			WBGene00095693	Pristionchus pacificus	From_analysis	WormBase-Compara
			WBGene00266046	Strongyloides ratti	From_analysis	WormBase-Compara
			WBGene00287280	Trichuris muris	From_analysis	WormBase-Compara
			WBGene00296870	Trichuris muris	From_analysis	WormBase-Compara
			FB:FBgn0015794	Drosophila melanogaster	From_analysis	EnsEMBL-Compara
						Hieranoid
						Inparanoid
						OMA
						OrthoInspector
						Panther
						PhylomeDB
						SonicParanoid
			ZFIN:ZDB-GENE-030131-3980	Danio rerio	From_analysis	Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						PhylomeDB
						SonicParanoid
			ZFIN:ZDB-GENE-040801-185	Danio rerio	From_analysis	Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						PhylomeDB
						SonicParanoid
			HGNC:14244	Homo sapiens	From_analysis	Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						PhylomeDB
						SonicParanoid
			MGI:102790	Mus musculus	From_analysis	Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						PhylomeDB
						SonicParanoid
			RGD:1308905	Rattus norvegicus	From_analysis	Hieranoid
						Inparanoid
						OMA
						OrthoFinder
						OrthoInspector
						Panther
						PhylomeDB
						SonicParanoid
		Paralog (32)
		Structured_description	Concise_description	rab-18 encodes a small GTPase homologous to the Rab GTPases that function in endocytosis, membrane fusion, and vesicular trafficking events; the precise biological role and expression pattern of rab-18 are not yet known.	Paper_evidence	WBPaper00015788
					Curator_confirmed	WBPerson1843
					Date_last_updated	17 Jun 2004 00:00:00
			Automated_description	Predicted to enable GTPase activity. Predicted to be involved in intracellular protein transport and lipid droplet organization. Predicted to be located in Golgi apparatus. Human ortholog(s) of this gene implicated in Warburg micro syndrome 3. Is an ortholog of human RAB18 (RAB18, member RAS oncogene family).	Paper_evidence	WBPaper00065943
					Curator_confirmed	WBPerson324
						WBPerson37462
					Inferred_automatically	This description was generated automatically by a script based on data from the WS291 version of WormBase
					Date_last_updated	29 Nov 2023 00:00:00
	Disease_info	Potential_model	DOID:0110718	Homo sapiens	Inferred_automatically	Inferred by orthology to human genes with DO annotation (HGNC:14244)
	Molecular_info	Corresponding_CDS	Y92C3B.3a
			Y92C3B.3b
		Corresponding_CDS_history	Y92C3B.3a:wp101
		Corresponding_transcript	Y92C3B.3a.1
			Y92C3B.3a.2
			Y92C3B.3b.1
			Y92C3B.3b.2
		Other_sequence (82)
		Associated_feature	WBsf650835
			WBsf981394
			WBsf991220
			WBsf226180
	Experimental_info	RNAi_result	WBRNAi00091946	Inferred_automatically	RNAi_primary
			WBRNAi00065403	Inferred_automatically	RNAi_primary
			WBRNAi00083707	Inferred_automatically	RNAi_primary
			WBRNAi00083565	Inferred_automatically	RNAi_primary
			WBRNAi00083796	Inferred_automatically	RNAi_primary
			WBRNAi00058626	Inferred_automatically	RNAi_primary
			WBRNAi00083371	Inferred_automatically	RNAi_primary
			WBRNAi00083543	Inferred_automatically	RNAi_primary
			WBRNAi00083602	Inferred_automatically	RNAi_primary
			WBRNAi00061380	Inferred_automatically	RNAi_primary
		Expr_pattern	Expr1019842
			Expr1032115
			Expr1162045
			Expr2015217
			Expr2033451
		Microarray_results (27)
		Expression_cluster (94)
		Interaction (12)
	Map_info	Map	III	Position	-24.4278	Error	0.161517
		Positive	Positive_clone	Y92C3B	Inferred_automatically	From CDS info
						From sequence, transcript, pseudogene data
		Mapping_data	Multi_point	5497
				5543
		Pseudo_map_position
	Reference (13)
	Remark	Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.	CGC_data_submission
	Method	Gene