WormBase Tree Display for Gene: WBGene00010055

WBGene00010055 SMap: S_parent: Sequence: CHROMOSOME_II
  Identity: Version: 2
    Name: CGC_name: dhgd-1 Person_evidence: WBPerson1997
            WBPerson41219
      Sequence_name: F54D5.12
      Molecular_name: F54D5.12
        F54D5.12.1
        CE26814
        F54D5.12.2
      Other_name: CELE_F54D5.12 Accession_evidence: NDB BX284602
      Public_name: dhgd-1
    DB_info: Database: AceView gene 2L830
        WormQTL gene WBGene00010055
        WormFlux gene WBGene00010055
        NDB locus_tag CELE_F54D5.12
        Panther gene CAEEL|WormBase=WBGene00010055|UniProtKB=G5EE46
          family PTHR43716
        NCBI gene 174764
        RefSeq protein NM_064064.9
        KEGG KEGG_id 1.1.99.39
        NemaPath KEGG_id 1.1.99.39
        TREEFAM TREEFAM_ID TF323342
        TrEMBL UniProtAcc G5EE46
        UniProt_GCRP UniProtAcc G5EE46
        OMIM gene 609186
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:51 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 04 Jan 2022 10:41:14 WBPerson1983 Name_change: CGC_name: dhgd-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: dhgd
    Allele (211)
    RNASeq_FPKM (74)
    GO_annotation: 00015395
      00015396
      00117545
      00117546
    Contained_in_operon: CEOP2556
    Ortholog (36)
    Paralog: WBGene00000081 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00009329 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00009334 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable catalytic activity and flavin adenine dinucleotide binding activity. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in D-2-hydroxyglutaric aciduria 1. Is an ortholog of human D2HGDH (D-2-hydroxyglutarate dehydrogenase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0111351 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:28358)
  Molecular_info: Corresponding_CDS: F54D5.12
    Corresponding_CDS_history: F54D5.12:wp42
    Corresponding_transcript: F54D5.12.1
      F54D5.12.2
    Other_sequence (33)
    Associated_feature (11)
  Experimental_info: RNAi_result: WBRNAi00094880 Inferred_automatically: RNAi_primary
      WBRNAi00048309 Inferred_automatically: RNAi_primary
      WBRNAi00021225 Inferred_automatically: RNAi_primary
      WBRNAi00015616 Inferred_automatically: RNAi_primary
      WBRNAi00032788 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1020051
      Expr1034386
      Expr1152110
      Expr2004148
      Expr2022372
    Regulate_expr_cluster: WBPaper00065272:dhgd-1(tm6671)_downregulated
      WBPaper00065272:dhgd-1(tm6671)_upregulated
    Microarray_results (21)
    Expression_cluster (175)
    Interaction: WBInteraction000104924
      WBInteraction000139868
      WBInteraction000140207
      WBInteraction000140350
      WBInteraction000141829
      WBInteraction000141944
      WBInteraction000142602
      WBInteraction000146403
      WBInteraction000146404
      WBInteraction000176276
      WBInteraction000185466
      WBInteraction000185467
      WBInteraction000185468
      WBInteraction000185469
      WBInteraction000191776
      WBInteraction000194729
      WBInteraction000244691
      WBInteraction000247124
      WBInteraction000252657
      WBInteraction000257361
      WBInteraction000262329
      WBInteraction000272955
      WBInteraction000273598
      WBInteraction000276796
      WBInteraction000297073
      WBInteraction000309273
      WBInteraction000311909
      WBInteraction000384844
      WBInteraction000389800
      WBInteraction000439077
      WBInteraction000439861
      WBInteraction000450852
      WBInteraction000473128
      WBInteraction000474778
      WBInteraction000475249
      WBInteraction000520823
      WBInteraction000521079
      WBInteraction000544465
      WBInteraction000548197
      WBInteraction000551725
      WBInteraction000563865
      WBInteraction000571138
      WBInteraction000573689
      WBInteraction000574425
      WBInteraction000578603
  Map_info: Map: II Position: 3.74919
    Positive: Positive_clone: F54D5 Inferred_automatically: From sequence, transcript, pseudogene data
  Reference: WBPaper00038491
    WBPaper00055090
    WBPaper00060111
    WBPaper00063953
    WBPaper00065272
  Remark: [220202 skd] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (3.74151)
  Method: Gene