WormBase Tree Display for Gene: WBGene00000882

WBGene00000882 SMap: S_parent: Sequence: F42G9
  Identity: Version: 2
    Name: CGC_name: cyn-6 Person_evidence: WBPerson466
      Sequence_name: F42G9.2
      Molecular_name: F42G9.2
        F42G9.2.1
        CE01301
      Other_name: cyp-6 Person_evidence: WBPerson466
        CELE_F42G9.2 Accession_evidence: NDB BX284603
      Public_name: cyn-6
    DB_info: Database: AceView gene 3B391
        WormQTL gene WBGene00000882
        WormFlux gene WBGene00000882
        NDB locus_tag CELE_F42G9.2
        Panther gene CAEEL|WormBase=WBGene00000882|UniProtKB=P52014
          family PTHR11071
        NCBI gene 175231
        RefSeq protein NM_064856.7
        KEGG KEGG_id 5.2.1.8
        NemaPath KEGG_id 5.2.1.8
        SwissProt UniProtAcc P52014
        TREEFAM TREEFAM_ID TF354259
        UniProt_GCRP UniProtAcc P52014
        OMIM gene 123841
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 20 Sep 2004 16:20:03 WBPerson1971 Name_change: CGC_name: cyp-6 -> cyn-6
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cyn
    Allele (14)
    Legacy_information: [C.elegansII] NMK. Cyclophilin family. Signal peptide. Cosmid C51B6. [TP]
    RNASeq_FPKM (74)
    GO_annotation (11)
    Ortholog (35)
    Paralog (18)
    Structured_description: Concise_description: cyn-6 encodes a cyclophilin most similar to human secreted cyclophilin type B isoforms that is functional when expressed in E. coli; it is expressed in the intestine. Paper_evidence: WBPaper00002472
            WBPaper00005482
            WBPaper00026884
          Curator_confirmed: WBPerson48
            WBPerson1843
          Date_last_updated: 20 Mar 2007 00:00:00
      Automated_description: Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Expressed in intestine. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 9. Is an ortholog of human PPIB (peptidylprolyl isomerase B). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0110349 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9255)
  Molecular_info: Corresponding_CDS: F42G9.2
    Corresponding_transcript: F42G9.2.1
    Other_sequence: PT04104
      AS01562
      RS06060
      Acan_isotig17815
      FE920113.1
      XI03787
      CR00527
      NB07237
      Tcol_isotig12750
      HS01081
      MHC08498_1
      TVC00084_1
      XI00567
      MI01232
      Dviv_isotig10701
      GPC03225_1
      BU586459.1
      CN477818.1
      XI04046
      MHC03950_1
      ES740797.1
      GR979168.1
      MCC00825_1
      TV00358
      Acan_isotig06375
      GRC03112_1
      MC00225
      CJC02284_1
      CRC01947_1
      GO252584.1
      OOC02049_1
      MH02081
      MH02914
      EX537831.1
      PTC03567_1
      MPC01511_1
      NBC02918_1
      TVC01248_1
      TSC01680_1
      ALC00189_1
      GR367818.1
      RS08408
      GR11913
      HC03877
      JK315029.1
      EX544231.1
      MH01061
      Dviv_isotig10700
      Dviv_isotig10699
      TMC01104_1
      TS00144
      RSC01443_1
      TS02400
      RS07233
      Acan_isotig06374
      HSC00971_1
      MPC01526_1
      XIC01537_1
      BM277183.1
      RS06078
      RSC00704_1
      TV01443
      GPC02930_1
      BG577520.1
      MA03346
      MHC09263_1
      BXC05532_1
      MHC02607_1
      SC00124
      MH10391
      TS03183
      CN477827.1
      GP00336
      GR978899.1
      BE239171.1
      TMC00570_1
    Associated_feature: WBsf654939
      WBsf658581
  Experimental_info: RNAi_result: WBRNAi00076416 Inferred_automatically: RNAi_primary
      WBRNAi00027816 Inferred_automatically: RNAi_primary
      WBRNAi00014849 Inferred_automatically: RNAi_primary
      WBRNAi00006569 Inferred_automatically: RNAi_primary
      WBRNAi00047133 Inferred_automatically: RNAi_primary
      WBRNAi00022707 Inferred_automatically: RNAi_primary
      WBRNAi00090595 Inferred_automatically: RNAi_primary
      WBRNAi00022708 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1991
      Expr1024208
      Expr1030547
      Expr1151001
      Expr2010674
      Expr2028914
    Drives_construct: WBCnstr00010563
      WBCnstr00037224
    Construct_product: WBCnstr00010563
      WBCnstr00037224
    Microarray_results (19)
    Expression_cluster (222)
    SAGE_tag (15)
    Interaction: WBInteraction000036390
      WBInteraction000037119
      WBInteraction000037123
      WBInteraction000037126
      WBInteraction000037129
      WBInteraction000042211
      WBInteraction000047516
      WBInteraction000047517
      WBInteraction000048836
      WBInteraction000049488
      WBInteraction000110644
      WBInteraction000120399
      WBInteraction000136532
      WBInteraction000142710
      WBInteraction000143486
      WBInteraction000147106
      WBInteraction000148267
      WBInteraction000148703
      WBInteraction000150321
      WBInteraction000151487
      WBInteraction000151594
      WBInteraction000156767
      WBInteraction000157959
      WBInteraction000157960
      WBInteraction000157961
      WBInteraction000158377
      WBInteraction000158610
      WBInteraction000159296
      WBInteraction000162911
      WBInteraction000167088
      WBInteraction000167089
      WBInteraction000167090
      WBInteraction000167091
      WBInteraction000167682
      WBInteraction000167691
      WBInteraction000176370
      WBInteraction000179437
      WBInteraction000181649
      WBInteraction000185317
      WBInteraction000188563
      WBInteraction000188599
      WBInteraction000188874
      WBInteraction000189017
      WBInteraction000190576
      WBInteraction000192773
      WBInteraction000193948
      WBInteraction000195063
      WBInteraction000197397
      WBInteraction000200394
      WBInteraction000202665
      WBInteraction000205941
      WBInteraction000206217
      WBInteraction000211261
      WBInteraction000213400
      WBInteraction000214059
      WBInteraction000222294
      WBInteraction000222810
      WBInteraction000226133
      WBInteraction000227652
      WBInteraction000230420
      WBInteraction000230903
      WBInteraction000232861
      WBInteraction000239035
      WBInteraction000239758
      WBInteraction000242150
      WBInteraction000254351
      WBInteraction000254352
      WBInteraction000254353
      WBInteraction000256008
      WBInteraction000258911
      WBInteraction000259134
      WBInteraction000261100
      WBInteraction000267272
      WBInteraction000267281
      WBInteraction000274230
      WBInteraction000274382
      WBInteraction000282415
      WBInteraction000286312
      WBInteraction000286751
      WBInteraction000291656
      WBInteraction000295313
      WBInteraction000295796
      WBInteraction000300839
      WBInteraction000304966
      WBInteraction000308120
      WBInteraction000318546
      WBInteraction000321619
      WBInteraction000324273
      WBInteraction000326711
      WBInteraction000328123
      WBInteraction000333286
      WBInteraction000335781
      WBInteraction000340715
      WBInteraction000340862
      WBInteraction000341166
      WBInteraction000343449
      WBInteraction000348348
      WBInteraction000352626
      WBInteraction000352627
      WBInteraction000357703
      WBInteraction000360581
      WBInteraction000366188
      WBInteraction000370260
      WBInteraction000379832
      WBInteraction000386889
      WBInteraction000388442
      WBInteraction000392858
      WBInteraction000393918
      WBInteraction000395106
      WBInteraction000397407
      WBInteraction000402684
      WBInteraction000403678
      WBInteraction000403884
      WBInteraction000404710
      WBInteraction000419151
      WBInteraction000422254
      WBInteraction000425513
      WBInteraction000432470
      WBInteraction000433201
      WBInteraction000441981
      WBInteraction000442105
      WBInteraction000442623
      WBInteraction000449177
      WBInteraction000454885
      WBInteraction000459809
      WBInteraction000461548
      WBInteraction000462389
      WBInteraction000462390
      WBInteraction000465508
      WBInteraction000465669
      WBInteraction000466967
      WBInteraction000467073
      WBInteraction000467601
      WBInteraction000467602
      WBInteraction000468021
      WBInteraction000468022
      WBInteraction000468257
      WBInteraction000469082
      WBInteraction000469333
      WBInteraction000471516
      WBInteraction000471974
      WBInteraction000543361
  Map_info: Map: III Position: -26.1239 Error: 0.022372
    Positive: Positive_clone: C51B6 Author_evidence: Page AM
        F42G9 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00002472
    WBPaper00005482
    WBPaper00015191
    WBPaper00024704
    WBPaper00026884
    WBPaper00033090
    WBPaper00038491
    WBPaper00055090
    WBPaper00065331
  Remark: signal_peptide
    [Page AM] Initially identified by the sequencing project. Referred to as cypB homolog by Blast analysis. cDNA clone isolated
    PPIase or cyclophilin, EC 5.2.1.8
    This gene has been renamed with approval of the CGC (cyp-6->cyn-6) Person_evidence: WBPerson466
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene