WormBase Tree Display for Gene: WBGene00002051
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| WBGene00002051 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name (5) | |||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ifa | ||||||||
| Allele (42) | |||||||||
| Strain | WBStrain00036840 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (12) | |||||||||
| Ortholog (69) | |||||||||
| Paralog (12) | |||||||||
| Structured_description | Concise_description | ifa-3 encodes an essential intermediate filament protein that is coexpressed with the essential IF protein IFB-1; IFA-3 is required for survival past early larval stages, correct positioning of excretory canals and body muscles, attachment of cuticle to hypodermis, and locomotion; IFA-3 forms heteropolymeric intermediate filaments in vitro with an equimolar mixture of IFB-1; IFA-3 is expressed in embryonic and larval, but not adult, hypodermis. | Paper_evidence (3) | ||||||
| Curator_confirmed | WBPerson567 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in several processes, including heterochromatin formation; nucleus organization; and protein localization to nuclear envelope. Predicted to be located in nuclear envelope and nuclear lamina. Expressed in hypodermis and ventral cord neurons. Human ortholog(s) of this gene implicated in partial lipodystrophy; primary autosomal recessive microcephaly; and progressive myoclonus epilepsy 9. Is an ortholog of human LMNB2 (lamin B2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS292 version of WormBase | ||||||||
| Date_last_updated | 24 Apr 2024 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111450 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||
| DOID:0070296 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||||
| DOID:0080299 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||||
| Molecular_info | Corresponding_CDS | F52E10.5 | |||||||
| Corresponding_CDS_history | F52E10.5:wp83 | ||||||||
| F52E10.5:wp102 | |||||||||
| F52E10.5:wp106 | |||||||||
| Corresponding_transcript | F52E10.5.1 | ||||||||
| Other_sequence (33) | |||||||||
| Associated_feature | WBsf718810 | ||||||||
| WBsf238387 | |||||||||
| WBsf238388 | |||||||||
| Experimental_info | RNAi_result (16) | ||||||||
| Expr_pattern | Expr1496 | ||||||||
| Expr1020134 | |||||||||
| Expr1031204 | |||||||||
| Expr1151810 | |||||||||
| Expr2012677 | |||||||||
| Expr2030913 | |||||||||
| Drives_construct | WBCnstr00008111 | ||||||||
| WBCnstr00036493 | |||||||||
| Construct_product | WBCnstr00008111 | ||||||||
| WBCnstr00036493 | |||||||||
| Microarray_results (16) | |||||||||
| Expression_cluster (161) | |||||||||
| Interaction (71) | |||||||||
| Map_info | Map | X | Position | 23.7263 | Error | 0.00238 | |||
| Positive | Positive_clone | F52E10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (17) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
