WormBase Tree Display for Gene: WBGene00004048
expand all nodes | collapse all nodes | view schema
WBGene00004048 | Evidence | CGC_data_submission | |||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | K04B12 | ||||||
Identity | Version | 1 | |||||||
Name | CGC_name | plx-2 | Person_evidence | WBPerson644 | |||||
Sequence_name | K04B12.1 | ||||||||
Molecular_name | K04B12.1 | ||||||||
K04B12.1.1 | |||||||||
CE53912 | |||||||||
Other_name | cep-1 | Paper_evidence | WBPaper00018146 | ||||||
WBPaper00023469 | |||||||||
WBPaper00011906 | |||||||||
CELE_K04B12.1 | Accession_evidence | NDB | BX284602 | ||||||
Public_name | plx-2 | ||||||||
DB_info | Database | AceView | gene | 2O704 | |||||
WormQTL | gene | WBGene00004048 | |||||||
WormFlux | gene | WBGene00004048 | |||||||
NDB | locus_tag | CELE_K04B12.1 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00004048|UniProtKB=O45657 | |||||||
family | PTHR22625 | ||||||||
NCBI | gene | 175101 | |||||||
RefSeq | protein | NM_001377900.1 | |||||||
SwissProt | UniProtAcc | O45657 | |||||||
UniProt_GCRP | UniProtAcc | O45657 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | plx | ||||||||
Allele (139) | |||||||||
Strain | WBStrain00029146 | ||||||||
WBStrain00029147 | |||||||||
WBStrain00029148 | |||||||||
WBStrain00029149 | |||||||||
WBStrain00030125 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (30) | |||||||||
Ortholog (31) | |||||||||
Paralog | WBGene00004047 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
Panther | |||||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | plx-2 encodes one of two C. elegans plexins, conserved transmembrane proteins that function as semaphorin receptors in both vertebrates and invertebrates; plx-2 activity is essential for proper male tail and epidermal morphogenesis and for normal axon guidance in a select group of neurons, including SDQL; genetic analyses indicate that plx-2 functions with mab-20/semaphorin-2a, efn-4/ephrin-4, and unc-129/TGF-beta to regulate male tail morphogenesis and with mab-20 and lad-2/L1CAM to mediate axon guidance; PLX-2 can bind MAB-20 and this interaction is enhanced in the presence of LAD-2; PLX-2::GFP reporters are expressed in a subset of neurons and epidermal cells, as well as a subset (1, 3, 5, and 7) of male sensory ray cell clusters. | Paper_evidence | WBPaper00006490 | |||||
WBPaper00029396 | |||||||||
WBPaper00031430 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 23 Jul 2008 00:00:00 | ||||||||
Automated_description | Enables semaphorin receptor activity. Involved in several processes, including axonal fasciculation; nematode larval development; and nematode male tail tip morphogenesis. Located in cell leading edge and cell surface. Expressed in several structures, including P3/4L; P9/10L; P9/10R; neuroblasts; and ray structural cell. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | K04B12.1 | |||||||
Corresponding_CDS_history | K04B12.1:wp92 | ||||||||
K04B12.1:wp109 | |||||||||
K04B12.1:wp180 | |||||||||
K04B12.1:wp274 | |||||||||
Corresponding_transcript | K04B12.1.1 | ||||||||
Other_sequence | Dviv_isotig22187 | ||||||||
FC552303.1 | |||||||||
ACC17590_1 | |||||||||
FC551755.1 | |||||||||
JI164274.1 | |||||||||
Acan_isotig12889 | |||||||||
Dviv_isotig33737 | |||||||||
Dviv_isotig33915 | |||||||||
Oden_isotig23212 | |||||||||
Associated_feature | WBsf666369 | ||||||||
WBsf666370 | |||||||||
WBsf717833 | |||||||||
WBsf717834 | |||||||||
WBsf717835 | |||||||||
WBsf990707 | |||||||||
WBsf990708 | |||||||||
WBsf990709 | |||||||||
WBsf990710 | |||||||||
WBsf990711 | |||||||||
WBsf990712 | |||||||||
WBsf990713 | |||||||||
WBsf1013840 | |||||||||
WBsf1013841 | |||||||||
WBsf1013842 | |||||||||
WBsf1013843 | |||||||||
WBsf224273 | |||||||||
Experimental_info | RNAi_result | WBRNAi00065915 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00016577 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00049879 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00000986 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr2929 | ||||||||
Expr4682 | |||||||||
Expr10005 | |||||||||
Expr1023808 | |||||||||
Expr1031948 | |||||||||
Expr1153584 | |||||||||
Expr1200099 | |||||||||
Expr2014968 | |||||||||
Expr2033203 | |||||||||
Drives_construct (15) | |||||||||
Construct_product | WBCnstr00000486 | ||||||||
WBCnstr00035722 | |||||||||
Microarray_results (21) | |||||||||
Expression_cluster (209) | |||||||||
Interaction (29) | |||||||||
WBProcess | WBbiopr:00000025 | ||||||||
Map_info (4) | |||||||||
Reference (148) | |||||||||
Remark | Sequence connection from [Takagi S] | ||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
[wm99ab616], [wm2001p535], and [jwm2000ab65] used cep-1 as an unapproved name for CGC plx-2 (K04B12.1). The CGC cep-1 (F52B5.5) is a p53 homolog | |||||||||
Method | Gene |