WormBase Tree Display for Gene: WBGene00001824
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WBGene00001824 | Evidence | CGC_data_submission | |||||
---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | F13D11 | ||||
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | hbl | ||||||
Allele (73) | |||||||
Possibly_affected_by | WBVar02152888 | ||||||
Strain (11) | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (19) | |||||||
Ortholog (32) | |||||||
Paralog | WBGene00016189 | Caenorhabditis elegans | From_analysis | Panther | |||
WBGene00005009 | Caenorhabditis elegans | From_analysis | Panther | ||||
WBGene00003033 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00008762 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00012385 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
Structured_description | Concise_description | hbl-1 encodes a C2H2-type zinc finger transcription factor related to Drosophila hunchback; hbl-1 is a heterochronic gene that plays an essential role in regulating developmental timing during postembryonic development; accordingly, mutations in hbl-1 affect locomotion, egg laying, body morphology, and hypodermal differentiation; hbl-1 is expressed in hypodermal precursor cells, neuronal precursor cells, and pharyngeal cells during embryogenesis and is primarily expressed in neurons during larval development; hbl-1 expression is negatively regulated by the let-7 miRNA whose expression is, in turn, negatively regulated by HBL-1 in a negative feedback loop. | Paper_evidence | WBPaper00003392 | |||
WBPaper00005908 | |||||||
WBPaper00005909 | |||||||
WBPaper00034754 | |||||||
Curator_confirmed | WBPerson48 | ||||||
WBPerson1843 | |||||||
Date_last_updated | 20 Aug 2009 00:00:00 | ||||||
Automated_description | Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including egg-laying behavior; negative regulation of transcription by RNA polymerase II; and nematode larval development. Located in nucleus. Expressed in several structures, including body wall musculature; germ line; hypodermis; neurons; and ventral nerve cord. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | F13D11.2a | |||||
F13D11.2b | |||||||
Corresponding_CDS_history | F13D11.2:wp155 | ||||||
Corresponding_transcript | F13D11.2a.1 | ||||||
F13D11.2b.1 | |||||||
Other_sequence | JI462622.1 | ||||||
JI164262.1 | |||||||
Oden_isotig23540 | |||||||
SC01112 | |||||||
JI164529.1 | |||||||
MI07402 | |||||||
MIC06569_1 | |||||||
GR977958.1 | |||||||
Associated_feature | WBsf019183 | ||||||
WBsf019184 | |||||||
WBsf019185 | |||||||
WBsf019186 | |||||||
WBsf019187 | |||||||
WBsf019188 | |||||||
WBsf019189 | |||||||
WBsf019190 | |||||||
WBsf019191 | |||||||
WBsf019192 | |||||||
WBsf019193 | |||||||
WBsf019194 | |||||||
WBsf662821 | |||||||
WBsf662822 | |||||||
WBsf662823 | |||||||
WBsf662824 | |||||||
WBsf662825 | |||||||
WBsf662826 | |||||||
WBsf662827 | |||||||
WBsf662828 | |||||||
WBsf662829 | |||||||
WBsf662830 | |||||||
WBsf716625 | |||||||
WBsf716626 | |||||||
WBsf718598 | |||||||
WBsf978668 | |||||||
WBsf1005398 | |||||||
WBsf1005399 | |||||||
WBsf1005400 | |||||||
WBsf1005401 | |||||||
WBsf1005402 | |||||||
WBsf1005403 | |||||||
WBsf1005404 | |||||||
WBsf1023016 | |||||||
WBsf1023017 | |||||||
WBsf1023018 | |||||||
WBsf1023019 | |||||||
WBsf1023020 | |||||||
WBsf1023021 | |||||||
WBsf235756 | |||||||
WBsf235757 | |||||||
WBsf235758 | |||||||
WBsf235759 | |||||||
Transcription_factor | WBTranscriptionFactor000175 | ||||||
Experimental_info | RNAi_result (78) | ||||||
Expr_pattern (15) | |||||||
Drives_construct (11) | |||||||
Construct_product | WBCnstr00000374 | ||||||
WBCnstr00009982 | |||||||
WBCnstr00017352 | |||||||
WBCnstr00019440 | |||||||
WBCnstr00036665 | |||||||
Microarray_results (27) | |||||||
Expression_cluster (229) | |||||||
Interaction (217) | |||||||
Anatomy_function | WBbtf0427 | ||||||
WBProcess | WBbiopr:00000083 | ||||||
Map_info | Map | X | Position | -4.26909 | Error | 0.011372 | |
Positive | Positive_clone | F13D11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 4396 | |||||
Pseudo_map_position | |||||||
Reference (125) | |||||||
Remark | Sequence connection from [Abrahante JE, Rougvie AE] | ||||||
old_name lin-57 becomes new_name hbl-1 from [Abrahante JE, Rougvie AE]. | |||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |