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WormBase Tree Display for Gene: WBGene00017089

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Name Class

WBGene00017089SMapS_parentSequenceE01A2
IdentityVersion2
NameCGC_namepoml-2Person_evidenceWBPerson10017
WBPerson95
Sequence_nameE01A2.7
Molecular_nameE01A2.7
E01A2.7.1
CE24874
Other_nameCELE_E01A2.7Accession_evidenceNDBBX284601
Public_namepoml-2
DB_infoDatabaseAceViewgene1E712
WormQTLgeneWBGene00017089
WormFluxgeneWBGene00017089
NDBlocus_tagCELE_E01A2.7
PanthergeneCAEEL|WormBase=WBGene00017089|UniProtKB=Q966L1
familyPTHR11799
NCBIgene171999
RefSeqproteinNM_058905.5
TREEFAMTREEFAM_IDTF322436
TrEMBLUniProtAccQ966L1
UniProt_GCRPUniProtAccQ966L1
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:58WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
213 Apr 2012 16:55:20WBPerson2970Name_changeCGC_namepoml-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpoml
AlleleWBVar01993114
WBVar00257480
WBVar00043176
WBVar00331924
WBVar00331925
WBVar00331926
WBVar00630615
WBVar00630616
WBVar00630617
WBVar00093082
WBVar00630618
WBVar00630619
WBVar00630620
WBVar00630621
WBVar00630622
WBVar00630623
WBVar02083856
WBVar00630624
WBVar00630625
WBVar01956854
WBVar01640859
WBVar01846300
WBVar01281523
WBVar01281524
WBVar01499786
WBVar01281525
WBVar01281526
WBVar01499985
WBVar00536490
WBVar01498959
StrainWBStrain00032254
RNASeq_FPKM (74)
GO_annotation00091003
00091004
00122569
Ortholog (57)
ParalogWBGene00003170Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00010775Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00077701Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00044697Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionThe E01A2.7 gene encodes one of five paraoxonase-like proteins; it is homologous to the human genes PARAOXONASE 1 gene (PON1, OMIM:168820) and PARAOXONASE 2 (OMIM:602447), which in some allelic forms are associated with susceptibility to coronary artery disease or to variations in fasting plasma glucose.Paper_evidenceWBPaper00005591
Curator_confirmedWBPerson1823
WBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable arylesterase activity and metal ion binding activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); eye disease (multiple); and hematologic cancer (multiple). Is an ortholog of human PON1 (paraoxonase 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (48)
Molecular_infoCorresponding_CDSE01A2.7
Corresponding_transcriptE01A2.7.1
Other_sequenceOden_isotig15033
CJC01469_1
Tcir_isotig22284
Oden_isotig15034
FK802982.1
ES413786.1
Associated_featureWBsf664125
WBsf219243
Experimental_infoRNAi_resultWBRNAi00043561Inferred_automaticallyRNAi_primary
WBRNAi00033607Inferred_automaticallyRNAi_primary
WBRNAi00023692Inferred_automaticallyRNAi_primary
WBRNAi00023396Inferred_automaticallyRNAi_primary
WBRNAi00023980Inferred_automaticallyRNAi_primary
WBRNAi00023180Inferred_automaticallyRNAi_primary
WBRNAi00003308Inferred_automaticallyRNAi_primary
Expr_patternExpr1013081
Expr1037347
Expr1147555
Expr2014997
Expr2033232
Drives_constructWBCnstr00027577
Construct_productWBCnstr00027577
Microarray_results (19)
Expression_cluster (155)
Interaction (2)
Map_infoMapIPosition-1.69879
PositivePositive_cloneE01A2Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00055090
WBPaper00065080
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene