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WormBase Tree Display for Gene: WBGene00017012

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Name Class

WBGene00017012SMapS_parentSequenceD1009
IdentityVersion2
NameCGC_nameacs-22Person_evidenceWBPerson237
WBPerson9275
Sequence_nameD1009.1
Molecular_nameD1009.1a
D1009.1a.1
CE04285
D1009.1c
CE51329
D1009.1d
CE51246
D1009.1c.1
D1009.1d.1
Other_nameCELE_D1009.1Accession_evidenceNDBBX284606
Public_nameacs-22
DB_infoDatabaseAceViewgeneXJ557
WormQTLgeneWBGene00017012
WormFluxgeneWBGene00017012
NDBlocus_tagCELE_D1009.1
PanthergeneCAEEL|WormBase=WBGene00017012|UniProtKB=Q18916
familyPTHR43107
NCBIgene181138
RefSeqproteinNM_001392815.1
NM_001322629.4
NM_077108.6
TrEMBLUniProtAccQ18916
A0A131MBB2
A0A131MB92
UniProt_GCRPUniProtAccQ18916
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:58WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
213 Mar 2009 14:10:25WBPerson9133Name_changeCGC_nameacs-22
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classacs
AlleleWBVar02065390
WBVar01170929
WBVar01170930
WBVar02065391
WBVar02065392
WBVar01170931
WBVar00081644
WBVar01487374
WBVar01170932
WBVar00081645
WBVar01170933
WBVar01487375
WBVar00081646
WBVar01170934
WBVar00081647
WBVar01170935
WBVar00081648
WBVar00081649
WBVar01170936
WBVar00081650
WBVar01170937
WBVar01170938
WBVar00081652
WBVar02056543
WBVar00081653
WBVar01170939
WBVar02056544
WBVar02056545
WBVar00081655
WBVar01170940
WBVar02056546
WBVar01170941
WBVar01170942
WBVar01170943
WBVar01170944
WBVar01170945
WBVar01170946
WBVar01170947
WBVar01170948
WBVar01170949
WBVar01170950
WBVar01170951
WBVar01170952
WBVar02072663
WBVar01170953
WBVar01170954
WBVar01170955
WBVar00236553
WBVar00055926
WBVar00276183
WBVar00055931
WBVar01473641
WBVar01473642
WBVar01473643
WBVar01473644
WBVar01473645
WBVar01550807
WBVar01550808
WBVar00251982
WBVar01544508
WBVar01499963
WBVar01493157
WBVar00511731
WBVar00511732
WBVar00511733
WBVar00511734
WBVar00511735
WBVar00511736
WBVar00511737
WBVar00511738
WBVar00511739
WBVar00511740
WBVar00511741
WBVar01886326
WBVar00511742
WBVar01886327
WBVar00511743
WBVar01886328
WBVar00511744
WBVar01886329
WBVar00511745
WBVar00511746
WBVar01886330
WBVar01886331
WBVar00511747
WBVar01886332
WBVar00511748
WBVar00511749
WBVar01886333
WBVar01886334
WBVar01897660
WBVar01886335
WBVar00252017
WBVar01886336
WBVar01886337
WBVar00099419
WBVar01886338
WBVar01886339
WBVar01927805
WBVar00099420
WBVar00099421
WBVar01927806
WBVar01499642
WBVar01498722
WBVar01470311
WBVar01470312
WBVar01470313
WBVar01470314
WBVar01470315
WBVar01835777
WBVar01170901
WBVar01170902
WBVar01170903
WBVar01170904
WBVar01170905
WBVar01170906
WBVar01170907
WBVar01170908
WBVar01170909
WBVar01170910
WBVar01170911
WBVar01170912
WBVar02032831
WBVar01170913
WBVar02032832
WBVar01170914
WBVar01497108
WBVar01170915
WBVar01170916
WBVar01170917
WBVar01170918
WBVar01170919
WBVar01170920
WBVar01170921
WBVar01170922
WBVar01170923
WBVar01170924
WBVar01170925
WBVar01498960
WBVar01170926
WBVar01170927
WBVar01500067
WBVar02065389
WBVar01170928
StrainWBStrain00004763
RNASeq_FPKM (74)
GO_annotation00001951
00001952
00001953
00001954
00001955
00001956
00001957
00062816
Ortholog (44)
Paralog (17)
Structured_descriptionConcise_descriptionacs-22 encodes a protein homologous to the mammalian FATP1 and FATP4 fatty acid transport proteins (FATP)/very long chain fatty acid acyl-CoA synthetases; acs-22 functions redundantly with acs-20 to regulate formation of the cuticle surface barrier that prevents penetration of small molecules; acs-22 may affect cuticle development via its role in incorporation of very long chain fatty acids, but not other fatty acids, into sphingomyelin; an acs-22::gfp promoter fusion is expressed strongly in the intestine, with weaker expression seen in the pharynx, head neurons, and hypodermis.Paper_evidenceWBPaper00035868
Curator_confirmedWBPerson1843
Date_last_updated03 Feb 2010 00:00:00
Automated_descriptionPredicted to enable long-chain fatty acid transporter activity and long-chain fatty acid-CoA ligase activity. Predicted to be involved in triglyceride homeostasis. Located in endoplasmic reticulum. Expressed in head neurons; hypodermis; and pharynx. Human ortholog(s) of this gene implicated in obesity. Is an ortholog of human SLC27A1 (solute carrier family 27 member 1) and SLC27A4 (solute carrier family 27 member 4).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:9970Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10998)
Molecular_infoCorresponding_CDSD1009.1a
D1009.1c
D1009.1d
Corresponding_CDS_historyD1009.1b:wp271
Corresponding_transcriptD1009.1a.1
D1009.1c.1
D1009.1d.1
Other_sequence (52)
Associated_feature (16)
Experimental_infoRNAi_resultWBRNAi00043335Inferred_automaticallyRNAi_primary
WBRNAi00012490Inferred_automaticallyRNAi_primary
WBRNAi00030314Inferred_automaticallyRNAi_primary
WBRNAi00092595Inferred_automaticallyRNAi_primary
Expr_patternExpr8894
Expr1020922
Expr1037310
Expr1147315
Expr2009212
Expr2027449
Drives_constructWBCnstr00013588
WBCnstr00022751
WBCnstr00027639
Construct_product (3)
Microarray_results (28)
Expression_cluster (202)
Interaction (87)
Map_infoMapXPosition0.449566Error0.000197
PositivePositive_cloneD1009Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (15)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene