WormBase Tree Display for Gene: WBGene00016192
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WBGene00016192 | SMap | S_parent | Sequence | C28H8 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | bcl | |||||
Allele | WBVar01500260 | |||||
WBVar01396859 | ||||||
WBVar01396860 | ||||||
WBVar00398898 | ||||||
WBVar00398899 | ||||||
WBVar01500122 | ||||||
WBVar01500123 | ||||||
WBVar02143902 | ||||||
WBVar00830539 | ||||||
WBVar00830540 | ||||||
WBVar00830541 | ||||||
WBVar00830542 | ||||||
WBVar00830543 | ||||||
WBVar00830544 | ||||||
WBVar00830545 | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation | 00053020 | |||||
00053021 | ||||||
00053022 | ||||||
00053023 | ||||||
00053024 | ||||||
Ortholog (43) | ||||||
Structured_description | Concise_description | bcl-7 encodes the sole C. elegans member of the BCL7 family of proteins that contains human proteins, namely BCL7A and BCL7B, that are associated with malignant diseases; bcl-7 activity is required for proper terminal seam cell differentiation as well as for normal development of the distal tip cells of the somatic gonad and germ line; in controlling cell development and differentiation, bcl-7 interacts with the Wnt signaling pathway, regulating the asymmetric localization of WRM-1, and hence POP-1, in asymmetric cell divisions; bcl-7 may also function to regulate apoptosis, as loss of bcl-7 activity results in increased expression of ced-9; a BCL-7::GFP reporter is expressed ubiquitously and localized to nuclei; mammalian BCL7 family members are members of Swi/Snf transcriptional regulatory complexes. | Paper_evidence | WBPaper00046304 | ||
Curator_confirmed | WBPerson1843 | |||||
WBPerson1823 | ||||||
WBPerson567 | ||||||
Date_last_updated | 20 May 2014 00:00:00 | |||||
Automated_description | Predicted to be involved in Wnt signaling pathway; apoptotic process; and cell differentiation. Predicted to be located in nucleus. Expressed in distal tip cell; germ cell; and gonadal sheath cell. Is an ortholog of human BCL7A (BAF chromatin remodeling complex subunit BCL7A). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Molecular_info | Corresponding_CDS | C28H8.1 | ||||
Corresponding_transcript | C28H8.1.1 | |||||
Other_sequence | Acan_isotig14735 | |||||
Oden_isotig13379 | ||||||
CBC13479_1 | ||||||
Tcir_isotig09201 | ||||||
CJC05531_1 | ||||||
Dviv_isotig33085 | ||||||
Tcol_contig20712 | ||||||
Oden_isotig13380 | ||||||
JI180958.1 | ||||||
Associated_feature | WBsf645222 | |||||
WBsf645223 | ||||||
WBsf225029 | ||||||
Experimental_info | RNAi_result | WBRNAi00061740 | Inferred_automatically | RNAi_primary | ||
WBRNAi00114621 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00029301 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00011309 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00005962 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00076175 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00041425 | Inferred_automatically | RNAi_primary | ||||
Expr_pattern | Expr12126 | |||||
Expr1015868 | ||||||
Expr1036929 | ||||||
Expr1145455 | ||||||
Expr2009584 | ||||||
Expr2027821 | ||||||
Drives_construct | WBCnstr00008715 | |||||
WBCnstr00020228 | ||||||
WBCnstr00020229 | ||||||
WBCnstr00028256 | ||||||
Construct_product | WBCnstr00008715 | |||||
WBCnstr00020228 | ||||||
WBCnstr00020229 | ||||||
WBCnstr00028256 | ||||||
Microarray_results (21) | ||||||
Expression_cluster (121) | ||||||
Interaction (67) | ||||||
Map_info | Map | III | Position | -1.43385 | ||
Positive | Positive_clone | C28H8 | Inferred_automatically | From sequence, transcript, pseudogene data | ||
Pseudo_map_position | ||||||
Reference | WBPaper00032961 | |||||
WBPaper00038491 | ||||||
WBPaper00046304 | ||||||
WBPaper00055090 | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
Method | Gene |