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WormBase Tree Display for Gene: WBGene00015975

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Name Class

WBGene00015975SMapS_parentSequenceC18E3
IdentityVersion2
NameCGC_namecas-2Person_evidenceWBPerson95
Sequence_nameC18E3.6
Molecular_nameC18E3.6a
C18E3.6a.1
CE27714
C18E3.6b
CE49852
C18E3.6b.1
C18E3.6c
Other_nameCELE_C18E3.6Accession_evidenceNDBBX284601
Public_namecas-2
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:56WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
208 Oct 2007 08:52:24WBPerson2970Name_changeCGC_namecas-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcas
AlleleWBVar00630930
WBVar00630931
WBVar00630932
WBVar00630933
WBVar00630934
WBVar00630935
WBVar00630936
WBVar01499919
WBVar00256384
WBVar00092884
WBVar01801326
WBVar01499786
WBVar01303917
WBVar00152826
WBVar01499985
WBVar01398919
WBVar00043311
WBVar00275886
WBVar00275887
WBVar01475364
WBVar01475365
WBVar01475366
WBVar01475367
WBVar01475368
WBVar01475369
WBVar00332019
WBVar01475370
WBVar01475371
WBVar00262382
WBVar00233547
WBVar00262386
WBVar01411492
WBVar00630908
WBVar00630909
WBVar00630910
WBVar00630911
WBVar00630912
WBVar01281637
WBVar01281638
WBVar00630913
WBVar00630914
WBVar01281640
WBVar01281641
WBVar00630915
WBVar01281642
WBVar00630916
WBVar01281643
WBVar00630917
WBVar00630918
WBVar00630919
WBVar00630920
WBVar00630921
WBVar00630922
WBVar00630923
WBVar00630924
WBVar01498959
WBVar00630925
WBVar00630926
WBVar00630927
WBVar00630928
WBVar00630929
StrainWBStrain00032161
RNASeq_FPKM (74)
GO_annotation (12)
Contained_in_operonCEOP1152
Ortholog (41)
ParalogWBGene00000294Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00022028Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionAutomated_descriptionEnables adenyl-nucleotide exchange factor activity. Involved in regulation of actin filament polymerization. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human CAP1 (cyclase associated actin cytoskeleton regulatory protein 1) and CAP2 (cyclase associated actin cytoskeleton regulatory protein 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:1793Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:20040)
DOID:12930Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:20039)
Molecular_infoCorresponding_CDSC18E3.6a
C18E3.6b
Corresponding_CDS_historyC18E3.6:wp93
Corresponding_transcriptC18E3.6c
C18E3.6a.1
C18E3.6b.1
Other_sequence (12)
Associated_featureWBsf217496
WBsf217497
Experimental_infoRNAi_resultWBRNAi00029078Inferred_automaticallyRNAi_primary
WBRNAi00117035Inferred_automaticallyRNAi_primary
WBRNAi00040941Inferred_automaticallyRNAi_primary
WBRNAi00002989Inferred_automaticallyRNAi_primary
WBRNAi00114660Inferred_automaticallyRNAi_primary
WBRNAi00095808Inferred_automaticallyRNAi_primary
WBRNAi00057898Inferred_automaticallyRNAi_primary
WBRNAi00000408Inferred_automaticallyRNAi_primary
Expr_patternExpr1025857
Expr1036829
Expr1144987
Expr2009723
Expr2027962
Drives_constructWBCnstr00028409
Construct_productWBCnstr00028409
Microarray_results (20)
Expression_cluster (118)
SAGE_tagSAGE:aatatgtgcgStrandSense
Unambiguously_mapped
SAGE:catccaaggcStrandAntisense
SAGE:agttctttgaStrandAntisense
SAGE:ctgagtcttcStrandSense
Unambiguously_mapped
SAGE:actaggagtctatttttStrandSense
Unambiguously_mapped
SAGE:catccaaggcgattcaaStrandAntisense
SAGE:aatatgtgcgacaacatStrandSense
Unambiguously_mapped
Interaction (29)
Map_infoMapIPosition-1.61175Error0.006372
PositivePositive_cloneC18E3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00042407
WBPaper00050235
WBPaper00051469
WBPaper00055090
WBPaper00064339
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene