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WormBase Tree Display for Gene: WBGene00015813

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Name Class

WBGene00015813SMapS_parentSequenceC16A3
IdentityVersion3
NameCGC_namethoc-2Person_evidenceWBPerson4055
Sequence_nameC16A3.8
Molecular_nameC16A3.8
C16A3.8.1
CE47895
Other_nametag-213
CELE_C16A3.8Accession_evidenceNDBBX284603
Public_namethoc-2
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:56WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
222 Dec 2004 16:59:41WBPerson2970Name_changeCGC_nametag-213
320 Jul 2007 11:50:19WBPerson2970Name_changeCGC_namethoc-2
Other_nametag-213
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classthoc
AlleleWBVar00062182
WBVar01500260
WBVar01656836
WBVar01656837
WBVar01995364
WBVar01995365
WBVar01995366
WBVar00833192
WBVar00833193
WBVar00833194
WBVar00833195
WBVar00833196
WBVar00833197
WBVar00833198
WBVar00833199
WBVar00833200
WBVar00833201
WBVar00833202
WBVar00833203
WBVar00833204
WBVar00833205
WBVar00833206
WBVar00833207
WBVar00833208
WBVar00833209
WBVar00833210
WBVar00833211
WBVar00833212
WBVar00833213
WBVar00833214
WBVar00833215
WBVar00833216
WBVar00833217
WBVar00833218
WBVar00833219
WBVar00833220
WBVar00833221
WBVar00833222
WBVar01330470
WBVar00833223
WBVar00833224
WBVar00833225
WBVar00833226
WBVar00833227
WBVar00092232
WBVar00833228
WBVar00833229
WBVar00833230
WBVar01686774
WBVar01893515
WBVar00250313
WBVar01264357
WBVar01264359
WBVar00602671
WBVar00399693
WBVar00399694
WBVar00399695
WBVar00399696
WBVar00275858
WBVar00399697
WBVar00399698
WBVar00399699
WBVar00399700
WBVar00399701
WBVar00399702
WBVar00399703
WBVar00399704
WBVar00399705
WBVar00399706
WBVar02132158
WBVar02132159
WBVar01566665
WBVar00314765
StrainWBStrain00035968
WBStrain00007859
WBStrain00007860
RNASeq_FPKM (74)
GO_annotation00060013
00060014
00060015
00060016
00060017
00060018
00121591
00121592
00121593
Contained_in_operonCEOP3856
Ortholog (48)
Structured_descriptionConcise_descriptionthoc-2 encodes the C. elegans ortholog of mammalian THOC2 and S. cerevisiae Tho2, conserved subunits of the THO complex involved in mRNP biogenesis as part of transcription elongation, mRNA maturation, and export; in C. elegans, thoc-2 activity is required for progression through the meiotic and mitotic cell cycles and thus for normal fertility and organismal development.Paper_evidenceWBPaper00041879
WBPaper00041588
Curator_confirmedWBPerson1843
Date_last_updated09 Jan 2013 00:00:00
Automated_descriptionPredicted to enable mRNA binding activity. Predicted to be involved in mRNA export from nucleus. Predicted to be located in nucleus. Predicted to be part of THO complex part of transcription export complex. Human ortholog(s) of this gene implicated in X-linked intellectual disability-short stature-overweight syndrome. Is an ortholog of human THOC2 (THO complex subunit 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0112056Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:19073)
Molecular_infoCorresponding_CDSC16A3.8
Corresponding_transcriptC16A3.8.1
Other_sequence (18)
Associated_featureWBsf645262
WBsf659065
WBsf659066
WBsf659067
WBsf659068
WBsf225088
WBsf225089
Experimental_infoRNAi_result (17)
Expr_patternExpr13874
Expr1014929
Expr1036770
Expr1144713
Expr2017390
Expr2035529
Drives_constructWBCnstr00028546
Construct_productWBCnstr00028546
WBCnstr00040171
Microarray_results (21)
Expression_cluster (115)
Interaction (52)
Map_infoMapIIIPosition-1.3546Error0.007276
PositivePositive_cloneC16A3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4991
5627
Pseudo_map_position
ReferenceWBPaper00027412
WBPaper00038491
WBPaper00041209
WBPaper00041588
WBPaper00041879
WBPaper00043900
WBPaper00044440
WBPaper00044806
WBPaper00052341
WBPaper00055090
PictureWBPicture0000013093
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene