WormBase Tree Display for Gene: WBGene00011590

WBGene00011590 SMap: S_parent: Sequence: T07F10
  Identity: Version: 2
    Name: CGC_name: bus-19 Paper_evidence: WBPaper00028877
          Person_evidence: WBPerson261
      Sequence_name: T07F10.4
      Molecular_name: T07F10.4a
        T07F10.4a.1
        CE36194
        T07F10.4b
      Other_name: CELE_T07F10.4 Accession_evidence: NDB BX284605
      Public_name: bus-19
    DB_info: Database: WormQTL gene WBGene00011590
        WormFlux gene WBGene00011590
        NDB locus_tag CELE_T07F10.4
        Panther gene CAEEL|WormBase=WBGene00011590|UniProtKB=Q22316
          family PTHR43220
        NCBI gene 179766
        RefSeq protein NM_001047697.5
            NR_003174.1
        TREEFAM TREEFAM_ID TF314301
        TrEMBL UniProtAcc Q22316
        UniProt_GCRP UniProtAcc Q22316
        RNAcentral URSid URS0000511154
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:52 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 01 Feb 2007 10:30:33 WBPerson2970 Name_change: CGC_name: bus-19
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: bus
    Allele: WBVar00145058
      WBVar00473740
      WBVar01057817
      WBVar00473741
      WBVar01057818
      WBVar00473742
      WBVar01057819
      WBVar00473743
      WBVar01057820
      WBVar00473744
      WBVar01057821
      WBVar00473745
      WBVar01057822
      WBVar01057823
      WBVar00473746
      WBVar01057824
      WBVar00473747
      WBVar01057825
      WBVar00473748
      WBVar00473749
      WBVar01057826
      WBVar00473750
      WBVar00473751
      WBVar00473752
      WBVar00473753
      WBVar00473754
      WBVar00473755
      WBVar01868560
      WBVar01868561
      WBVar01868562
      WBVar01868563
      WBVar01868564
      WBVar01868565
      WBVar01868566
      WBVar01868567
      WBVar01868568
      WBVar01868569
      WBVar01868570
      WBVar01868571
      WBVar01868572
      WBVar01868573
      WBVar01868574
      WBVar01868575
      WBVar01868576
      WBVar01868577
      WBVar01868578
      WBVar01868579
      WBVar01868580
      WBVar00257130
      WBVar02061582
      WBVar02061583
      WBVar02061584
      WBVar02061585
      WBVar02061586
      WBVar01808902
      WBVar00254578
      WBVar01462290
      WBVar01462291
      WBVar01462292
      WBVar01462293
      WBVar01462294
      WBVar01495399
      WBVar01549199
      WBVar01057752
      WBVar01057753
      WBVar01057754
      WBVar02111886
      WBVar01057755
      WBVar01057756
      WBVar01057757
      WBVar01057758
      WBVar00256091
      WBVar01057759
      WBVar01057760
      WBVar01057761
      WBVar02115575
      WBVar01057762
      WBVar01057763
      WBVar01057764
      WBVar01057765
      WBVar01057766
      WBVar01057767
      WBVar01057768
      WBVar01057769
      WBVar01057770
      WBVar02024432
      WBVar01057771
      WBVar02043653
      WBVar01057772
      WBVar02043654
      WBVar01057773
      WBVar02137341
      WBVar01057774
      WBVar01057775
      WBVar01057776
      WBVar01500212
      WBVar01057777
      WBVar01500213
      WBVar01057778
      WBVar01975172
      WBVar01057779
      WBVar01057780
      WBVar01975173
      WBVar00011260
      WBVar01057781
      WBVar01057782
      WBVar00011265
      WBVar01057783
      WBVar01499299
      WBVar01057784
      WBVar01057785
      WBVar01057786
      WBVar00011270
      WBVar01057787
      WBVar01057788
      WBVar00011275
      WBVar01057789
      WBVar01057790
      WBVar01057791
      WBVar01057792
      WBVar00011280
      WBVar01057793
      WBVar01057794
      WBVar00277216
      WBVar01057795
      WBVar01057796
      WBVar01057797
      WBVar01057798
      WBVar01057799
      WBVar01057800
      WBVar00145049
      WBVar01499316
      WBVar01057801
      WBVar01057802
      WBVar01057803
      WBVar01057804
      WBVar01057805
      WBVar01057806
      WBVar01057807
      WBVar00145057
      WBVar01057808
      WBVar01057809
      WBVar00145059
      WBVar00145060
      WBVar01057810
      WBVar01057811
      WBVar01743765
      WBVar01743766
      WBVar00473735
      WBVar01057812
      WBVar01743767
      WBVar01057813
      WBVar00473736
      WBVar01057814
      WBVar01743768
      WBVar00473737
      WBVar00473738
      WBVar01057815
      WBVar01743769
      WBVar00473739
      WBVar01743770
      WBVar01057816
    Strain: WBStrain00004692
      WBStrain00004699
      WBStrain00004700
    RNASeq_FPKM (74)
    GO_annotation (2)
    Ortholog (33)
    Paralog: WBGene00006520 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00013513 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
    Structured_description: Concise_description: bus-19 encodes an ancient but unfamiliar transmembrane protein required for colonization by Microbacterium nematophilum and the tail-swelling response to M. nematophilum infection, as well as for cuticle integrity and traction during movement, normal alae and body shape, dauer formation, normally rapid growth, and larval viability; BUS-19 (along with Y71A12C.2) is orthologous to human TMEM41A, and paralogous to TAG-175/D2013.10 and human TMEM41B; both BUS-19 and TAG-175 are orthologous to plant and fungal proteins such as budding yeast Tvp38p, and bacterial proteins such as Geobacter metallireducens DedA; given its orthology with Tvp38p, BUS-19 may colocalize to late Golgi vesicles with the Tlg2p ortholog SYN-16 and with a variety of other protein ligands. Paper_evidence: WBPaper00028877
            WBPaper00030783
            WBPaper00030784
            WBPaper00030785
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jul 2007 00:00:00
      Automated_description: Predicted to be located in membrane. Is an ortholog of human TMEM41A (transmembrane protein 41A). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: T07F10.4a
    Corresponding_CDS_history: T07F10.4:wp114
    Corresponding_transcript: T07F10.4b
      T07F10.4a.1
    Other_sequence (20)
    Associated_feature (18)
  Experimental_info: RNAi_result: WBRNAi00052771 Inferred_automatically: RNAi_primary
      WBRNAi00035312 Inferred_automatically: RNAi_primary
      WBRNAi00090769 Inferred_automatically: RNAi_primary
      WBRNAi00090768 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1018972
      Expr1035108
      Expr1156378
      Expr2009686
      Expr2027925
    Drives_construct: WBCnstr00030536
    Construct_product: WBCnstr00030536
    Microarray_results (25)
    Expression_cluster (211)
    Interaction (49)
  Map_info: Map: V Position: 4.72059
    Positive: Positive_clone: T07F10 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00028877
    WBPaper00038491
    WBPaper00052104
    WBPaper00055090
    WBPaper00058949
    WBPaper00062563
    WBPaper00063192
    WBPaper00065106
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
    [140923 pad] Modified Map position as it was a reverse physical that could not be fixed by automated methods.
  Method: Gene