WormBase Tree Display for Gene: WBGene00006410

WBGene00006410 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: ZK470
  Identity: Version: 2
    Name: CGC_name: nck-1 Person_evidence: WBPerson103
      Sequence_name: ZK470.5
      Molecular_name: ZK470.5a
        ZK470.5a.1
        CE31270
        ZK470.5b
        CE53627
        ZK470.5b.1
      Other_name: tag-22 Person_evidence: WBPerson201
        CELE_ZK470.5 Accession_evidence: NDB BX284606
      Public_name: nck-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:40 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 24 Aug 2005 11:18:38 WBPerson2970 Name_change: CGC_name: nck-1
                Other_name: tag-22
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: nck
    Allele: WBVar02158410
      WBVar00250623
      WBVar00091978
      WBVar00258743
      WBVar01914197
      WBVar01601478
      WBVar01601479
      WBVar01570893
      WBVar02048763
      WBVar02048764
      WBVar02048765
      WBVar01819560
      WBVar01980314
      WBVar01980315
      WBVar01980316
      WBVar01980317
      WBVar01980318
      WBVar00077541
      WBVar02079794
      WBVar00077542
      WBVar00077543
      WBVar00077544
      WBVar00077545
      WBVar00077546
      WBVar00077547
      WBVar00077548
      WBVar00077549
      WBVar00077550
      WBVar00251430
      WBVar02111102
      WBVar00091678
      WBVar02044698
      WBVar02044699
      WBVar02044700
      WBVar02044701
      WBVar01758140
      WBVar02044702
      WBVar02076286
      WBVar01138578
      WBVar01138579
      WBVar01138580
      WBVar01138581
      WBVar01138582
      WBVar01138583
      WBVar01138584
      WBVar01138585
      WBVar01138586
      WBVar01138587
      WBVar01138588
      WBVar01138589
      WBVar00500703
      WBVar00500704
      WBVar01138590
      WBVar00500705
      WBVar01138591
      WBVar01138592
      WBVar00500706
      WBVar00500707
      WBVar01138593
      WBVar02071443
      WBVar02071444
      WBVar00500708
      WBVar01138594
      WBVar01138595
      WBVar02151344
      WBVar00500709
      WBVar00500710
      WBVar01138596
      WBVar00500711
      WBVar00260860
      WBVar01138597
      WBVar01138598
      WBVar00500712
      WBVar00500713
      WBVar01138599
      WBVar01138600
      WBVar00500714
      WBVar01138601
      WBVar01138602
      WBVar01138603
      WBVar01138604
      WBVar01138605
      WBVar01138606
      WBVar01499636
      WBVar02026998
      WBVar01825183
      WBVar01825184
      WBVar01825185
      WBVar01825186
      WBVar01825187
      WBVar01486786
      WBVar01814688
      WBVar01814689
      WBVar01814690
      WBVar01814691
      WBVar01814692
      WBVar01814693
      WBVar01814694
      WBVar01814695
      WBVar01814696
      WBVar01814697
      WBVar01814698
      WBVar01814699
      WBVar01500067
    Strain: WBStrain00002409
      WBStrain00002332
      WBStrain00031573
      WBStrain00035589
    RNASeq_FPKM (74)
    GO_annotation: 00087952
      00087953
      00087954
      00087955
      00087956
      00087957
      00087958
      00087959
      00087960
    Ortholog (44)
    Paralog: WBGene00004774 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: nck-1 encodes an SH2/SH3 domain-containing protein orthologous to the human NCK adaptor proteins that link tyrosine kinase signaling to actin cytoskeleton reorganization; in C. elegans, nck-1 activity is required for excretory canal migration and full axon migration in mechanosensory neurons; a nck-1::gfp promoter fusion is expressed in the excretory cell and ventral cord motorneurons. Paper_evidence: WBPaper00032514
          Curator_confirmed: WBPerson48
            WBPerson1843
          Date_last_updated: 21 Aug 2009 00:00:00
      Automated_description: Predicted to enable receptor tyrosine kinase binding activity and signaling adaptor activity. Predicted to be involved in cell migration and signal transduction. Located in cytoplasm and nucleus. Expressed in several structures, including egg-laying apparatus; gonad; hypodermis; neuroblasts; and neurons. Is an ortholog of human NCK1 (NCK adaptor protein 1) and NCK2 (NCK adaptor protein 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS (2)
    Corresponding_CDS_history: ZK470.5b:wp272
    Corresponding_transcript: ZK470.5a.1
      ZK470.5b.1
    Other_sequence (15)
    Associated_feature (19)
  Experimental_info: RNAi_result (12)
    Expr_pattern (18)
    Drives_construct: WBCnstr00002061
      WBCnstr00003001
      WBCnstr00004496
      WBCnstr00013363
      WBCnstr00013801
      WBCnstr00013802
      WBCnstr00013803
      WBCnstr00014491
      WBCnstr00034367
    Construct_product: WBCnstr00013802
      WBCnstr00013803
      WBCnstr00014490
      WBCnstr00014491
      WBCnstr00014494
      WBCnstr00021621
      WBCnstr00034367
    Antibody: WBAntibody00002579
      WBAntibody00003056
    Microarray_results (31)
    Expression_cluster (130)
    Interaction (107)
  Map_info: Map: X Position: -8.1368 Error: 0.089595
    Positive: Positive_clone: ZK470 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4949
        5017
    Pseudo_map_position
  Reference (21)
  Remark: Gene name created from parsing 'genotype' field from CGC strain information CGC_data_submission
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene