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WormBase Tree Display for Gene: WBGene00004237

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Name Class

WBGene00004237EvidenceCGC_data_submission
SMapS_parentSequenceCHROMOSOME_I
IdentityVersion1
NameCGC_nameptr-23Person_evidenceWBPerson349
Sequence_nameZK270.1
Molecular_nameZK270.1
ZK270.1.1
CE15305
ZK270.1.2
Other_nameCELE_ZK270.1Accession_evidenceNDBBX284601
Public_nameptr-23
DB_infoDatabaseAceViewgene1P503
WormQTLgeneWBGene00004237
WormFluxgeneWBGene00004237
NDBlocus_tagCELE_ZK270.1
PanthergeneCAEEL|WormBase=WBGene00004237|UniProtKB=G5EE13
familyPTHR10796
NCBIgene173362
RefSeqproteinNM_061202.7
TREEFAMTREEFAM_IDTF331806
TrEMBLUniProtAccG5EE13
UniProt_GCRPUniProtAccG5EE13
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:34WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classptr
AlleleWBVar00218911
WBVar01498978
WBVar01498979
WBVar01499908
WBVar00267685
WBVar02066913
WBVar00267686
WBVar01499739
WBVar01557770
WBVar01557771
WBVar00543385
WBVar01357689
WBVar00543386
WBVar00543387
WBVar00296664
WBVar01894844
WBVar00252370
WBVar01231944
WBVar01489684
WBVar01499627
WBVar01499628
WBVar01499999
WBVar00353522
WBVar00353523
WBVar00353524
WBVar00353525
WBVar00353526
WBVar01290706
WBVar01499823
WBVar00353527
WBVar00353528
WBVar01715249
WBVar01502768
WBVar00353529
WBVar01715250
WBVar01502769
WBVar00353530
WBVar01502770
WBVar00353531
WBVar00353532
WBVar00353533
WBVar00694782
WBVar00694783
WBVar00694784
WBVar00694785
WBVar00694786
WBVar00694787
WBVar00694788
WBVar00694789
WBVar00694790
WBVar00694791
WBVar01236607
WBVar00694792
WBVar00694793
WBVar00694794
WBVar00694795
WBVar00694796
WBVar00694797
WBVar00694798
WBVar00694799
WBVar00694800
WBVar00694801
WBVar01499298
WBVar00694802
WBVar00694803
WBVar00694804
WBVar00694805
WBVar00694806
WBVar00694807
WBVar00694808
WBVar00694809
WBVar00694810
WBVar00694811
WBVar01498939
WBVar00694812
WBVar00694813
WBVar00694814
WBVar00694815
WBVar00694816
WBVar00694817
WBVar01500050
WBVar00694818
WBVar01412345
WBVar00694819
WBVar00694820
WBVar00694821
WBVar00694822
WBVar00694823
WBVar00694824
WBVar00694825
WBVar00694826
WBVar00162710
WBVar00694827
WBVar00162711
WBVar00162712
WBVar00162713
WBVar00162714
WBVar00162715
StrainWBStrain00037725
RNASeq_FPKM (74)
GO_annotation00015243
00015244
00015245
00015246
00015247
00015248
00015249
00015250
00112529
Ortholog (33)
Paralog (30)
Structured_descriptionConcise_descriptionptr-23 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-23 is strongly required for normal molting from L4 to adult stages (a role conserved in C. briggsae); PTR_23 also functions in a pathway with the mucin-like protein OSM-8 to regulate the osmotic stress response; PTR-23 activity is additionally required for normal male tail development, vulval morphogenesis, adult alae formation, and (partly) for endocytosis of yolk by oocytes; a PTR-23::GFP reporter fusion protein is expressed in the hypodermis where it localizes to discrete foci.Paper_evidenceWBPaper00024393
WBPaper00026763
WBPaper00026841
WBPaper00027263
WBPaper00027756
WBPaper00038064
Curator_confirmed (2)
Date_last_updated20 Apr 2011 00:00:00
Automated_descriptionInvolved in endocytosis and molting cycle. Acts upstream of or within nematode male tail mating organ morphogenesis. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Expressed in hypodermis.Paper_evidenceWBPaper00065943
Curator_confirmed (2)
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSZK270.1
Corresponding_transcript (2)
Other_sequence (54)
Associated_featureWBsf716513
WBsf986260
WBsf986261
WBsf986262
WBsf986263
WBsf1011308
WBsf1011309
WBsf1011310
WBsf218842
WBsf218843
Experimental_infoRNAi_result (25)
Expr_patternExpr11208
Expr1014683
Expr1032088
Expr1162752
Expr2015167
Expr2033405
Drives_constructWBCnstr00018221
WBCnstr00035615
Construct_productWBCnstr00018221
WBCnstr00035615
Microarray_results (23)
Expression_cluster (234)
Interaction (17)
Map_infoMapIPosition28.2667Error0.069277
PositivePositive_cloneZK270Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (18)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene