WormBase Tree Display for Gene: WBGene00003411

WBGene00003411 SMap: S_parent: Sequence: CHROMOSOME_X
  Identity: Version: 1
    Name: CGC_name: mrp-5 Person_evidence: WBPerson490
      Sequence_name: F14F4.3
      Molecular_name: F14F4.3
        F14F4.3.1
        CE23650
      Other_name: CELE_F14F4.3 Accession_evidence: NDB BX284606
      Public_name: mrp-5
    DB_info: Database: AceView gene XP558
        WormQTL gene WBGene00003411
        WormFlux gene WBGene00003411
        NDB locus_tag CELE_F14F4.3
        Panther gene CAEEL|WormBase=WBGene00003411|UniProtKB=G5EE72
          family PTHR24223
        NCBI gene 181587
        RefSeq protein NM_078078.4
        SwissProt UniProtAcc G5EE72
        UniProt_GCRP UniProtAcc G5EE72
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:31 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: mrp
    Allele: WBVar01499887
      WBVar01499519
      WBVar01499888
      WBVar01499710
      WBVar01782616
      WBVar01942259
      WBVar00525470
      WBVar00525471
      WBVar00525472
      WBVar00525473
      WBVar00525474
      WBVar00525475
      WBVar00093254
      WBVar00525476
      WBVar00525477
      WBVar00525478
      WBVar00525479
      WBVar00525480
      WBVar00525481
      WBVar00525482
      WBVar00525483
      WBVar00525484
      WBVar01528189
      WBVar00525485
      WBVar01528190
      WBVar00525486
      WBVar01528191
      WBVar00525487
      WBVar00525488
      WBVar00525489
      WBVar01897966
      WBVar00525490
      WBVar01760497
      WBVar01760498
      WBVar01760499
      WBVar01472725
      WBVar01472728
      WBVar00265233
      WBVar01928687
      WBVar00255480
      WBVar01928688
      WBVar01788245
      WBVar02035062
      WBVar02027725
      WBVar01211597
      WBVar01211598
      WBVar01211599
      WBVar01211600
      WBVar01211601
      WBVar01211602
      WBVar01211603
      WBVar01211604
      WBVar01211605
      WBVar01211606
      WBVar01211607
      WBVar01211608
      WBVar01211609
      WBVar01211610
      WBVar01211611
      WBVar00085825
      WBVar01211612
      WBVar00085826
      WBVar01211613
      WBVar00085827
      WBVar00313745
      WBVar00085828
      WBVar01211614
      WBVar00313746
      WBVar00085829
      WBVar01211615
      WBVar01211616
      WBVar00085830
      WBVar00313747
      WBVar00313748
      WBVar01211617
      WBVar00085831
      WBVar01211618
      WBVar00085833
      WBVar01211619
      WBVar00085834
      WBVar01211620
      WBVar01211621
      WBVar01211622
      WBVar01211623
      WBVar01211624
      WBVar01211625
      WBVar01211626
      WBVar01211627
      WBVar01211628
      WBVar01211629
      WBVar01211630
      WBVar01211631
      WBVar01211632
      WBVar01211633
      WBVar01211634
      WBVar01211635
      WBVar01211636
      WBVar01211637
      WBVar01211638
      WBVar00218863
      WBVar00218866
      WBVar01211639
      WBVar00218867
      WBVar01211640
      WBVar00218868
      WBVar01211641
      WBVar01211642
      WBVar01211643
      WBVar01211644
      WBVar01602546
      WBVar01211645
      WBVar01602547
      WBVar01211646
      WBVar01602548
      WBVar01211647
      WBVar01211648
      WBVar01211649
      WBVar01211650
      WBVar01211651
      WBVar01211652
      WBVar01211653
      WBVar01211654
      WBVar01498960
      WBVar01500067
    Strain (2)
    RNASeq_FPKM (74)
    GO_annotation (16)
    Ortholog (41)
    Paralog: WBGene00000477 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003407 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003408 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003409 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003410 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003412 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003414 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003413 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: The mrp-5 gene encodes a homolog of the human gene CFTR, which when mutated leads to cystic fibrosis (OMIM:219700). Paper_evidence: WBPaper00004424
            WBPaper00004637
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables ABC-type vitamin B12 transporter activity. Involved in cobalamin transport. Predicted to be located in membrane. Expressed in several structures, including body wall musculature; hypodermis; intestine; muscle cell; and pharynx. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human ABCC12 (ATP binding cassette subfamily C member 12) and ABCC5 (ATP binding cassette subfamily C member 5). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:1793 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:56)
  Molecular_info: Corresponding_CDS: F14F4.3
    Corresponding_CDS_history: F14F4.3a:wp252
    Corresponding_transcript: F14F4.3.1
    Other_sequence (48)
    Associated_feature (16)
  Experimental_info: RNAi_result (15)
    Expr_pattern (11)
    Drives_construct: WBCnstr00003311
      WBCnstr00011353
      WBCnstr00013720
      WBCnstr00019478
      WBCnstr00019480
      WBCnstr00036131
    Construct_product: WBCnstr00019479
      WBCnstr00019480
      WBCnstr00036131
    Microarray_results (23)
    Expression_cluster (188)
    Interaction (42)
  Map_info: Map: X Position: 21.5778 Error: 0.006227
    Positive: Positive_clone: F14F4 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (20)
  Remark: Sequence connection from [Sheps JA, Baillie DL] [040902 ck1]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene