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WormBase Tree Display for Gene: WBGene00002241

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Name Class

WBGene00002241SMapS_parentSequenceF10C2
IdentityVersion1
NameCGC_namekup-1Person_evidenceWBPerson71
Sequence_nameF10C2.2
Molecular_nameF10C2.2
F10C2.2.1
CE09306
Other_name (2)
Public_namekup-1
DB_infoDatabaseAceViewgene5M514
WormQTLgeneWBGene00002241
WormFluxgeneWBGene00002241
NDBlocus_tagCELE_F10C2.2
NCBIgene179651
RefSeqproteinNM_001392622.1
SwissProtUniProtAccP34705
UniProt_GCRPUniProtAccP34705
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:27WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classkup
AlleleWBVar01461958
WBVar01461961
WBVar01461962
WBVar01461963
WBVar00249716
WBVar02137225
WBVar01499547
WBVar01703170
WBVar01703171
WBVar01052512
WBVar01052513
WBVar01052514
WBVar01052515
WBVar01052516
WBVar01052517
WBVar01052518
WBVar01052519
WBVar01052520
WBVar01052521
WBVar01052522
WBVar01052523
WBVar01052524
WBVar01052525
WBVar00471947
WBVar01052526
WBVar00471948
WBVar00471949
WBVar01052527
WBVar01052528
WBVar00471950
WBVar00471951
WBVar01052529
WBVar01052530
WBVar00471952
WBVar00471953
WBVar01052531
WBVar01052532
WBVar00471954
WBVar01052533
WBVar00471955
WBVar01052534
WBVar00471956
WBVar00471957
WBVar01052535
WBVar00471958
WBVar01052536
WBVar01052537
WBVar00471959
WBVar01052538
WBVar00471960
WBVar00471961
WBVar01052539
WBVar00471962
WBVar01052540
WBVar01052541
WBVar00471963
WBVar01052542
WBVar01052543
WBVar01052544
WBVar01052545
WBVar01052546
WBVar01052547
WBVar01052548
WBVar01052549
WBVar01052550
WBVar01052551
WBVar02072534
WBVar01866600
WBVar02061243
WBVar01866601
WBVar02061244
WBVar01866602
WBVar01866603
WBVar02061245
WBVar01866604
WBVar01866605
WBVar01866606
WBVar01866607
WBVar01866608
WBVar01866609
WBVar01866610
WBVar01866611
WBVar01866612
WBVar01866613
WBVar01866614
WBVar00091745
WBVar01500212
WBVar01500213
WBVar01499299
WBVar01661226
WBVar00090793
WBVar00589751
WBVar00006370
WBVar00006375
WBVar00090805
WBVar00090806
WBVar00006380
WBVar01499316
WBVar00006385
Legacy_information[C.elegansII] NMK. Upstream in operon with kin-13. Encodes predicted 385 aa novel protein. Antibody stains nuclei of most cells. [Zorio et al. 1994; CR]
StrainWBStrain00035751
RNASeq_FPKM (74)
Contained_in_operonCEOP5312
Ortholog (27)
Structured_descriptionConcise_descriptionkup-1 encodes a novel protein that is conserved in C. briggsae, but contains no other known homologs; kup-1 is the upstream gene in an operon with pkc-1, which encodes two protein kinase C isoforms of the nPKC isotype; the polycistronic kup-1/pkc-1 mRNA is detected at low levels in embryos and larvae, but its expression greatly increases in adults; as loss of kup-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of kup-1 in C. elegans development and/or behavior is not yet known.Paper_evidenceWBPaper00001950
WBPaper00005493
WBPaper00005654
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnriched in several structures, including AVK; MSaapaapa; accessory cell; anterior arcade cell; and g2 based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; glp-1; and gld-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including rotenone; mianserin; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF10C2.2
Corresponding_transcriptF10C2.2.1
Other_sequence (42)
Associated_feature (30)
Experimental_infoRNAi_resultWBRNAi00044221Inferred_automaticallyRNAi_primary
WBRNAi00013038Inferred_automaticallyRNAi_primary
WBRNAi00085043Inferred_automaticallyRNAi_primary
Expr_patternExpr12857
Expr1021564
Expr1031316
Expr1148182
Expr2012983
Expr2031215
Drives_constructWBCnstr00022908
Microarray_results (20)
Expression_cluster (139)
InteractionWBInteraction000227835
WBInteraction000396019
WBInteraction000435475
WBInteraction000574965
WBInteraction000576308
Map_infoMapVPosition3.60848Error0.003861
PositivePositive_cloneF10C2Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4470
4586
Pseudo_map_position
ReferenceWBPaper00001723
WBPaper00002006
WBPaper00005493
WBPaper00010944
WBPaper00015440
WBPaper00022096
WBPaper00031335
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene