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WormBase Tree Display for Gene: WBGene00001099

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Name Class

WBGene00001099EvidencePaper_evidenceWBPaper00006232
WBPaper00005018
SMapS_parentSequenceK02D7
IdentityVersion1
NameCGC_namedsc-4Person_evidenceWBPerson247
Sequence_nameK02D7.4
Molecular_nameK02D7.4
K02D7.4.1
CE33667
Other_nameCELE_K02D7.4Accession_evidenceNDBBX284604
Public_namedsc-4
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:23WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdsc
AlleleWBVar00879571
WBVar00879572
WBVar01450068
WBVar00879573
WBVar00879574
WBVar00879575
WBVar00879576
WBVar00879577
WBVar00879578
WBVar00879579
WBVar01838873
WBVar00879580
WBVar00879581
WBVar00879582
WBVar00879583
WBVar00879584
WBVar01492905
WBVar00879585
WBVar00879586
WBVar00879587
WBVar00879588
WBVar00879589
WBVar01499166
WBVar00879590
WBVar00879591
WBVar00879592
WBVar00879593
WBVar00879594
WBVar01646884
WBVar00879595
WBVar00879596
WBVar00879597
WBVar00879598
WBVar00879599
WBVar01607450
WBVar01607451
WBVar01499384
WBVar01499385
WBVar01794532
WBVar01499608
WBVar02147963
WBVar01499633
WBVar00241271
WBVar00261617
WBVar01702370
WBVar00415017
WBVar00415018
WBVar00415019
WBVar00415020
WBVar00415021
WBVar00415022
WBVar00415023
WBVar00415024
WBVar00415025
WBVar01499498
WBVar00415026
WBVar01499499
WBVar02144045
WBVar01499328
WBVar01499329
StrainWBStrain00026671
RNASeq_FPKM (74)
GO_annotation (21)
Ortholog (35)
Structured_descriptionConcise_descriptiondsc-4 encodes the C. elegans ortholog of the large subunit of the microsomal triglyceride transfer protein; dsc-4 affects the length of the defecation cycle and genetically interacts with clk-1 with respect to defecation cycle length, and also with respect to the clk-1- dependent adjustment of defecation cycle length to temperature; a DSC-4::GFP fusion protein is expressed in the intestine beginning during embryonic elongation and continuing on through adulthood.Paper_evidenceWBPaper00005018
WBPaper00006232
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated15 Dec 2006 00:00:00
Automated_descriptionPredicted to enable lipid transfer activity and phospholipid transporter activity. Involved in lipoprotein transport and plasma lipoprotein particle assembly. Located in endoplasmic reticulum. Expressed in intestine. Human ortholog(s) of this gene implicated in several diseases, including abetalipoproteinemia; familial hypercholesterolemia; and hyperinsulinism. Is an ortholog of human MTTP (microsomal triglyceride transfer protein).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:9452Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7467)
DOID:13810Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7467)
DOID:9970Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7467)
DOID:0080208Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7467)
DOID:10763Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7467)
DOID:2018Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7467)
DOID:1386Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7467)
Molecular_infoCorresponding_CDSK02D7.4
Corresponding_CDS_historyK02D7.4:wp97
Corresponding_transcriptK02D7.4.1
Other_sequence (20)
Associated_featureWBsf651615
WBsf995119
WBsf229671
Experimental_infoRNAi_resultWBRNAi00090628Inferred_automaticallyRNAi_primary
WBRNAi00025848Inferred_automaticallyRNAi_primary
WBRNAi00085937Inferred_automaticallyRNAi_primary
WBRNAi00085914Inferred_automaticallyRNAi_primary
WBRNAi00049699Inferred_automaticallyRNAi_primary
WBRNAi00016449Inferred_automaticallyRNAi_primary
WBRNAi00027397Inferred_automaticallyRNAi_primary
Expr_patternExpr2799
Expr1022313
Expr1030700
Expr1153419
Expr2011102
Expr2029338
Drives_constructWBCnstr00010952
WBCnstr00037083
Construct_product (2)
Microarray_results (18)
Expression_cluster (215)
Interaction (59)
WBProcessWBbiopr:00000121
Map_infoMapIVPosition-26.6463Error0.02418
PositivePositive_cloneK02D7Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data2_point7143
Multi_point4691
5537
ReferenceWBPaper00005018
WBPaper00005432
WBPaper00006232
WBPaper00018895
WBPaper00026830
WBPaper00033099
WBPaper00042349
WBPaper00053100
WBPaper00061228
WBPaper00065331
Remarkdsc-4 complements flr-3(ut9)Person_evidenceWBPerson3095
MethodGene