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WormBase Tree Display for Gene: WBGene00000182

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Name Class

WBGene00000182SMapS_parentSequenceB0336
IdentityVersion3
NameCGC_namearf-1
Sequence_nameB0336.2
Molecular_nameB0336.2
B0336.2.1
CE00696
B0336.2.2
Other_nameARF/1
arf-1.2
CELE_B0336.2Accession_evidenceNDBBX284603
Public_namearf-1
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
205 Nov 2004 15:32:14WBPerson2970Name_changeCGC_namearf-1.2
310 Sep 2020 13:24:17WBPerson1983Name_changeCGC_namearf-1
Other_namearf-1.2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classarf
AlleleWBVar01263844
WBVar01500260
WBVar00398508
WBVar00398509
WBVar00398510
WBVar00398511
WBVar00398512
WBVar01500122
WBVar01500123
WBVar02015256
WBVar01644797
WBVar00092076
WBVar01995260
WBVar01837620
WBVar02150413
WBVar01710115
WBVar01710116
WBVar00829284
WBVar00829285
WBVar00829286
WBVar00829287
WBVar00829288
WBVar00829289
WBVar00829290
WBVar00829291
WBVar00829292
WBVar00061472
WBVar00829293
WBVar00829294
WBVar00829295
WBVar00829296
WBVar00829297
WBVar00829298
Legacy_information[C.elegansII] NMK. Encodes 181 aa predicted class I ARF. [CGC, MQ]
RNASeq_FPKM (74)
GO_annotation (22)
Contained_in_operonCEOP3332
Ortholog (45)
ParalogWBGene00000180Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000183Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000189Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000193Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000184Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000187Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000190Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000188Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00000192Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00001358Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00012132Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00021349Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00021841Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00022678Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionarf-1.2 encodes an ADP-ribosylation factor homolog required in vivo for embryonic development, fertility, locomotion, vulval development, and cuticular synthesis; ARF proteins are N-myristoylated GTPases that regulate membrane traffic and the actin cytoskeleton, and that activate both phospholipase D1 (PLD1) and phosphatidylinositol 4-phosphate 5-kinase.Paper_evidenceWBPaper00012958
WBPaper00013160
WBPaper00015195
Curator_confirmedWBPerson567
Date_last_updated16 Jul 2007 00:00:00
Automated_descriptionPredicted to enable GTP binding activity and GTPase activity. Involved in several processes, including oocyte development; regulation of apoptotic process involved in development; and regulation of receptor-mediated endocytosis. Located in endoplasmic reticulum. Expressed in pharyngeal muscle cell; uterus; ventral nerve cord; and vulval precursor cell. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Is an ortholog of human ARF1 (ADP ribosylation factor 1) and ARF3 (ADP ribosylation factor 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0050454Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:652)
Molecular_infoCorresponding_CDSB0336.2
Corresponding_transcriptB0336.2.1
B0336.2.2
Other_sequence (178)
Associated_feature (13)
Experimental_infoRNAi_result (38)
Expr_patternChronogram1686
Expr3149
Expr4834
Expr5055
Expr15679
Expr1028066
Expr1030106
Expr1143124
Expr2009391
Expr2027627
Drives_constructWBCnstr00002999
WBCnstr00011177
WBCnstr00012265
WBCnstr00019869
WBCnstr00037680
WBCnstr00042476
Construct_productWBCnstr00008785
WBCnstr00008786
WBCnstr00019869
WBCnstr00037680
WBCnstr00042476
Microarray_results (26)
Expression_cluster (132)
Interaction (182)
Map_infoMapIIIPosition-1.44726Error0.000356
PositivePositive_cloneB0336Inferred_automaticallyFrom sequence, transcript, pseudogene data
NM#G4
Mapping_dataMulti_point4788
5049
Pseudo_map_position
Reference (37)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
This gene was previously assigned the CGC name arf-1. It has been re-assigned to arf-1.2Curator_confirmedWBPerson2970
MethodGene