rsr-1 encodes the C. elegans homolog of the SRm160 (serine/arginine-repeat related nuclear matrix protein of 160kDa) splicing coactivator; rsr-1 is an essential gene that is required for development, including normal pharyngeal morphology.
Predicted to be involved in regulation of mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Expressed in hypodermis. Human ortholog(s) of this gene implicated in gestational diabetes. Is an ortholog of human SRRM1 (serine and arginine repetitive matrix 1).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.