WormBase Tree Display for Gene: WBGene00007413

WBGene00007413 SMap: S_parent: Sequence: CHROMOSOME_II
  Identity: Version: 2
    Name: CGC_name: pro-2 Paper_evidence: WBPaper00028280
          Person_evidence: WBPerson275
      Sequence_name: C07E3.2
      Molecular_name: C07E3.2
        C07E3.2.1
        CE47947
      Other_name: CELE_C07E3.2 Accession_evidence: NDB BX284602
      Public_name: pro-2
    DB_info: Database: AceView gene 2K630
        WormQTL gene WBGene00007413
        WormFlux gene WBGene00007413
        NDB locus_tag CELE_C07E3.2
        Panther gene CAEEL|WormBase=WBGene00007413|UniProtKB=O17580
          family PTHR12687
        NCBI gene 174598
        RefSeq protein NM_063823.6
        SwissProt UniProtAcc O17580
        TREEFAM TREEFAM_ID TF314829
        UniProt_GCRP UniProtAcc O17580
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:48 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 03 Oct 2006 13:25:52 WBPerson2970 Name_change: CGC_name: pro-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: pro
    Allele: WBVar02040531
      WBVar01499702
      WBVar02040532
      WBVar02068182
      WBVar02120799
      WBVar01498435
      WBVar02048007
      WBVar01604614
      WBVar01400325
      WBVar01604615
      WBVar02072300
      WBVar01604616
      WBVar01604617
      WBVar02120633
      WBVar01243823
      WBVar01243824
      WBVar01243825
      WBVar02121382
      WBVar01243827
      WBVar01895169
      WBVar01895170
      WBVar00761966
      WBVar00761967
      WBVar00375910
      WBVar00761968
      WBVar00761969
      WBVar00375911
      WBVar01378178
      WBVar00375912
      WBVar00761970
      WBVar00761971
      WBVar00375913
      WBVar00761972
      WBVar00375914
      WBVar01982671
      WBVar00228314
      WBVar00375915
      WBVar00761973
      WBVar02123975
      WBVar01378189
      WBVar00375916
      WBVar00761974
      WBVar00228315
      WBVar00375917
      WBVar01378200
      WBVar00761975
      WBVar02123976
      WBVar00228316
      WBVar00375918
      WBVar00228317
      WBVar00761976
      WBVar00375919
      WBVar00228318
      WBVar00761977
      WBVar00375920
      WBVar00761978
      WBVar00761979
      WBVar00761980
      WBVar00761981
      WBVar00761982
      WBVar00761983
      WBVar02121961
      WBVar00761984
      WBVar00761985
      WBVar00761986
      WBVar00761987
      WBVar00761988
      WBVar00105457
      WBVar00761989
      WBVar00090922
      WBVar01477883
      WBVar00761990
      WBVar00761991
      WBVar00761992
      WBVar00761993
      WBVar00761994
      WBVar00761995
      WBVar00761996
      WBVar02109826
      WBVar00761997
      WBVar00761998
      WBVar00761999
      WBVar00762000
      WBVar00762001
      WBVar01253661
      WBVar00762002
      WBVar00762003
      WBVar00762004
      WBVar00762005
      WBVar01253672
      WBVar01538560
      WBVar01627196
      WBVar01538561
      WBVar01720563
      WBVar01538562
      WBVar02092178
      WBVar01413874
      WBVar01439454
      WBVar01439455
      WBVar01439456
      WBVar01916819
      WBVar00234792
      WBVar02124394
      WBVar00234793
      WBVar02124767
      WBVar02018132
      WBVar01836133
      WBVar01836134
      WBVar01935392
      WBVar01935393
      WBVar01935394
      WBVar01311054
      WBVar01311055
      WBVar01311056
      WBVar01311058
      WBVar01405549
      WBVar01311059
      WBVar01311060
      WBVar01311061
      WBVar01311063
      WBVar01311065
      WBVar01498940
      WBVar01784416
      WBVar01311066
      WBVar01784417
      WBVar00238522
      WBVar00175034
      WBVar00175035
      WBVar00175036
    Strain: WBStrain00007711
    RNASeq_FPKM (74)
    GO_annotation (12)
    Contained_in_operon: CEOP2692
    Ortholog (32)
    Structured_description: Concise_description: pro-2 encodes the C. elegans ortholog of Saccharomyces cerevisiae Noc2p, which is required for intranuclear ribosome maturation and transport; in C. elegans, pro-2 activity is essential for larval growth, somatic gonad development, regulation of germline development and proliferation, and hence, fertility; by virtue of its similarity to Noc2p, PRO-2 is predicted to be a component of two heterodimeric intranuclear complexes that associate with, and aid in maturation of, different preribosomal particles. Paper_evidence: WBPaper00028280
            WBPaper00028281
          Curator_confirmed: WBPerson1843
          Date_last_updated: 01 Aug 2006 00:00:00
      Automated_description: Predicted to enable histone binding activity and transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and ribosomal large subunit biogenesis. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of Noc1p-Noc2p complex and Noc2p-Noc3p complex. Is an ortholog of human NOC2L (NOC2 like nucleolar associated transcriptional repressor). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C07E3.2
    Corresponding_transcript: C07E3.2.1
    Other_sequence (79)
    Associated_feature: WBsf666037
      WBsf989318
      WBsf223780
      WBsf223781
      WBsf223782
  Experimental_info: RNAi_result (12)
    Expr_pattern: Expr1010517
      Expr1033192
      Expr1144078
      Expr2015104
      Expr2033342
    Drives_construct: WBCnstr00033757
    Construct_product: WBCnstr00033757
    Microarray_results: SMD_C07E3.2
      186575_s_at
      A_12_P113754
      Aff_C07E3.2
      GPL13394_WBGene00007413
      GPL13914_C07E3.2
      GPL14144_C07E3.2_1589-1648_0.917_10_C
      GPL14144_C07E3.2_2095-2154_0.932_6_A
      GPL19516_CGZ0003206
      GPL8304_CE_WBGene00007413_A
      GPL8304_CE_WBGene00007413_C
      GPL8673_C07E3_2P01219
      GPL8673_C07E3_2P01622
      GPL9450_C07E3.2
      cea2.c.09650
    Expression_cluster (95)
    Interaction (263)
  Map_info: Map: II Position: 2.42251 Error: 0.00635
    Positive: Positive_clone: C07E3 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5697
        5698
        5699
      Pos_neg_data: 10762
  Reference: WBPaper00028280
    WBPaper00033795
    WBPaper00038491
    WBPaper00039470
    WBPaper00039496
    WBPaper00044530
    WBPaper00055090
    WBPaper00065308
  Method: Gene