WormBase Tree Display for Gene: WBGene00006424

WBGene00006424 SMap: S_parent: Sequence: F49E10
  Identity: Version: 3
    Name: CGC_name: ctbp-1 Person_evidence: WBPerson2627
      Sequence_name: F49E10.5
      Molecular_name: F49E10.5a
        F49E10.5a.1
        CE29966
        F49E10.5b
        CE47412
        F49E10.5b.1
      Other_name: tag-45 Person_evidence: WBPerson201
        CELE_F49E10.5 Accession_evidence: NDB BX284606
      Public_name: ctbp-1
    DB_info: Database: AceView gene XG491
        WormQTL gene WBGene00006424
        WormFlux gene WBGene00006424
        NDB locus_tag CELE_F49E10.5
        Panther gene CAEEL|WormBase=WBGene00006424|UniProtKB=Q20595
          family PTHR46029
        NCBI gene 180853
        RefSeq protein NM_001270102.3
            NM_001270101.4
        SwissProt UniProtAcc Q20595
        UniProt_GCRP UniProtAcc Q20595
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:40 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 05 Oct 2006 15:31:09 WBPerson2970 Event: Acquires_merge: WBGene00018642
        3 16 Oct 2006 14:08:57 WBPerson2970 Name_change: CGC_name: ctbp-1
                Other_name: tag-45
      Acquires_merge: WBGene00018642
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ctbp
    Allele: WBVar02157970
      WBVar01815638
      WBVar01815639
      WBVar01815640
      WBVar01830625
      WBVar01815641
      WBVar01815642
      WBVar01487009
      WBVar02125494
      WBVar01487010
      WBVar00309450
      WBVar02147869
      WBVar01526509
      WBVar02143789
      WBVar01495496
      WBVar01490910
      WBVar01550049
      WBVar01550050
      WBVar01550051
      WBVar01550052
      WBVar00600884
      WBVar01926821
      WBVar02145071
      WBVar02145072
      WBVar02145073
      WBVar02145074
      WBVar02145075
      WBVar01880227
      WBVar01880228
      WBVar01880229
      WBVar01880230
      WBVar01880231
      WBVar01880232
      WBVar01880233
      WBVar01880234
      WBVar01880235
      WBVar01880236
      WBVar01880237
      WBVar01880238
      WBVar01880239
      WBVar01880240
      WBVar01880241
      WBVar01474178
      WBVar01474179
      WBVar01474180
      WBVar01474181
      WBVar01474182
      WBVar01491143
      WBVar02027153
      WBVar01150386
      WBVar01150387
      WBVar01150388
      WBVar01150389
      WBVar01150390
      WBVar01801012
      WBVar01150391
      WBVar01150392
      WBVar01469104
      WBVar01469105
      WBVar01150393
      WBVar01469106
      WBVar01150394
      WBVar01469107
      WBVar02064022
      WBVar01150395
      WBVar01469108
      WBVar02064023
      WBVar01150396
      WBVar01150397
      WBVar02064024
      WBVar01150398
      WBVar02064025
      WBVar01758537
      WBVar01758538
      WBVar02064026
      WBVar01150399
      WBVar01150400
      WBVar02064027
      WBVar01150401
      WBVar02064028
      WBVar01150402
      WBVar00079452
      WBVar02064029
      WBVar01150403
      WBVar01150404
      WBVar01150405
      WBVar01150406
      WBVar01150407
      WBVar01150408
      WBVar01150409
      WBVar01150410
      WBVar01150411
      WBVar00300491
      WBVar01150412
      WBVar01150413
      WBVar01150414
      WBVar01150415
      WBVar00026731
      WBVar01150416
      WBVar02139365
      WBVar01150417
      WBVar02139366
      WBVar00026736
      WBVar01150418
      WBVar01150419
      WBVar01150420
      WBVar00026741
      WBVar01150421
      WBVar01150422
      WBVar01150423
      WBVar01150424
      WBVar00026746
      WBVar01150425
      WBVar01150426
      WBVar01820023
      WBVar01150427
      WBVar01150428
      WBVar01150429
      WBVar01150430
      WBVar01150431
      WBVar00504796
      WBVar01150432
      WBVar00504797
      WBVar02157252
      WBVar00504798
      WBVar01150433
      WBVar01150434
      WBVar00504799
      WBVar00504800
      WBVar01150435
      WBVar00259613
      WBVar00504801
      WBVar01150436
      WBVar00504802
      WBVar01150437
      WBVar00504803
      WBVar01150438
      WBVar00504804
      WBVar01150439
      WBVar00504805
      WBVar01150440
      WBVar00504806
      WBVar01150441
      WBVar00504807
      WBVar01150442
      WBVar00504808
      WBVar01150443
      WBVar00504809
      WBVar01150444
      WBVar01150445
      WBVar00504810
      WBVar01150446
      WBVar00504811
      WBVar01150447
      WBVar00504812
      WBVar01150448
      WBVar00504813
      WBVar00504814
      WBVar01150449
      WBVar01150450
      WBVar01150451
      WBVar01150452
      WBVar01150453
      WBVar01150454
      WBVar01150455
      WBVar01150456
      WBVar01150457
      WBVar01150458
      WBVar01150459
      WBVar01150460
      WBVar00261113
      WBVar00301417
      WBVar00091786
      WBVar02074520
      WBVar01500067
    Possibly_affected_by: WBVar02157252
    Strain: WBStrain00031454
      WBStrain00030103
      WBStrain00047496
    RNASeq_FPKM (74)
    GO_annotation (15)
    Ortholog (40)
    Paralog: WBGene00007836 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Provisional_description: tag-45 encodes a D-isomer specific 2-hydroxyacid dehydrogenase. Curator_confirmed: WBPerson48
      Concise_description: tag-45 encodes a D-isomer specific 2-hydroxyacid dehydrogenase.
      Automated_description: Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and transcription corepressor activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in hypodermis and nervous system. Used to study alcohol use disorder. Is an ortholog of human CTBP1 (C-terminal binding protein 1) and CTBP2 (C-terminal binding protein 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Experimental_model: DOID:1574 Homo sapiens Paper_evidence: WBPaper00041098
          Curator_confirmed: WBPerson324
          Date_last_updated: 21 May 2019 00:00:00
  Models_disease_asserted: WBDOannot00000674
  Molecular_info: Corresponding_CDS: F49E10.5a
      F49E10.5b
    Corresponding_transcript: F49E10.5a.1
      F49E10.5b.1
    Other_sequence (24)
    Associated_feature (20)
    Transcription_factor: WBTranscriptionFactor000823
  Experimental_info: RNAi_result: WBRNAi00015304 Inferred_automatically: RNAi_primary
      WBRNAi00103373 Inferred_automatically: RNAi_primary
      WBRNAi00047836 Inferred_automatically: RNAi_primary
      WBRNAi00015305 Inferred_automatically: RNAi_primary
      WBRNAi00047835 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr11825
      Expr12091
      Expr12092
      Expr12541
      Expr1025813
      Expr1032609
      Expr1151670
      Expr2010565
      Expr2028805
    Drives_construct: WBCnstr00019349
      WBCnstr00020016
      WBCnstr00021742
      WBCnstr00042043
      WBCnstr00042044
    Construct_product: WBCnstr00019349
      WBCnstr00020016
      WBCnstr00020017
      WBCnstr00021150
      WBCnstr00021742
    Microarray_results: SMD_F49E10.5
      SMD_F49E10.6
      174356_at
      187805_at
      189123_at
      A_12_P120248
      A_12_P163263
      Aff_F49E10.5
      Aff_F49E10.6
      GPL13394_WBGene00006424
      GPL13914_F49E10.5
      GPL14144_F49E10.5_1213-1272_0.897_17_A
      GPL14144_F49E10.5_1253-1312_0.896_19_B
      GPL14144_F49E10.5_1503-1562_0.848_58_C
      GPL19516_CGZ0022728
      GPL19516_CGZ0022729
      GPL21109_F49E10.5a
      GPL3518_CE29966
      GPL8304_CE_WBGene00006424_A
      GPL8304_CE_WBGene00006424_B
      GPL8673_F49E10_5P00924
      GPL8673_F49E10_5P01287
      GPL8673_F49E10_5P01692
      GPL9450_F49E10.5
      cea2.p.146286
    Expression_cluster (179)
    Interaction (71)
    WBProcess: WBbiopr:00000121
  Map_info: Map: X Position: -4.16195 Error: 0.01114
    Positive: Positive_clone: F49E10 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (26)
  Remark: Killed due to lack of data Curator_confirmed: WBPerson2970
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene