WormBase Tree Display for Gene: WBGene00000249
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| WBGene00000249 | SMap | S_parent | Sequence | T27F2 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | bir-1 | Person_evidence | WBPerson250 | |||||
| Sequence_name | T27F2.3 | ||||||||
| Molecular_name | T27F2.3 | ||||||||
| T27F2.3.1 | |||||||||
| CE06521 | |||||||||
| T27F2.3.2 | |||||||||
| Other_name | CELE_T27F2.3 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | bir-1 | ||||||||
| DB_info | Database | AceView | gene | 5M125 | |||||
| WormQTL | gene | WBGene00000249 | |||||||
| WormFlux | gene | WBGene00000249 | |||||||
| NDB | locus_tag | CELE_T27F2.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000249|UniProtKB=G5EFA2 | |||||||
| family | PTHR46771 | ||||||||
| NCBI | gene | 179597 | |||||||
| RefSeq | protein | NM_073548.10 | |||||||
| SwissProt | UniProtAcc | G5EFA2 | |||||||
| TREEFAM | TREEFAM_ID | TF316930 | |||||||
| UniProt_GCRP | UniProtAcc | G5EFA2 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | bir | ||||||||
| Allele | WBVar00090687 | ||||||||
| WBVar01499904 | |||||||||
| WBVar01499905 | |||||||||
| WBVar01499547 | |||||||||
| WBVar00262710 | |||||||||
| WBVar02156615 | |||||||||
| WBVar01500208 | |||||||||
| WBVar01500209 | |||||||||
| WBVar01500212 | |||||||||
| WBVar01500213 | |||||||||
| WBVar02061117 | |||||||||
| WBVar01499299 | |||||||||
| WBVar00471133 | |||||||||
| WBVar00471134 | |||||||||
| WBVar01050068 | |||||||||
| WBVar01499316 | |||||||||
| WBVar01050069 | |||||||||
| WBVar01050070 | |||||||||
| WBVar01050071 | |||||||||
| WBVar00598938 | |||||||||
| WBVar00598939 | |||||||||
| WBVar00598940 | |||||||||
| Strain | WBStrain00051386 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (21) | |||||||||
| Contained_in_operon | CEOP5296 | ||||||||
| Ortholog (34) | |||||||||
| Structured_description | Concise_description | bir-1 encodes a homolog of the baculoviral inhibitor-of-apoptosis (IAP) repeat (BIR) proteins (BIRPs) family; bir-1 is required for meiotic and mitotic chromosome segregation and for cytokinesis; BIR-1 localizes to meiotic and mitotic chromosomes and to the spindle midzone; BIR-1 forms a protein complex with CSC-1, ICP-1 and AIR-2. | Paper_evidence | WBPaper00004303 | |||||
| WBPaper00004589 | |||||||||
| WBPaper00005872 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 04 Mar 2013 00:00:00 | ||||||||
| Automated_description | Predicted to enable metal ion binding activity. Involved in several processes, including chromosome organization; egg-laying behavior; and inductive cell migration. Located in condensed chromosome and spindle midzone. Expressed in egg-laying apparatus; hypodermis; pharynx; rectal muscle; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); ductal carcinoma in situ; and endometrial hyperplasia. Is an ortholog of human BIRC5 (baculoviral IAP repeat containing 5). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0050866 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:593) | ||||
| DOID:9256 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:593) | ||||||
| DOID:11054 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:593) | ||||||
| DOID:2671 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:593) | ||||||
| DOID:0080365 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:593) | ||||||
| DOID:4450 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:593) | ||||||
| DOID:0060074 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:593) | ||||||
| DOID:10283 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:593) | ||||||
| DOID:6432 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:593) | ||||||
| Molecular_info | Corresponding_CDS | T27F2.3 | |||||||
| Corresponding_transcript | T27F2.3.1 | ||||||||
| T27F2.3.2 | |||||||||
| Other_sequence | CRC03813_1 | ||||||||
| CR07657 | |||||||||
| Associated_feature | WBsf647283 | ||||||||
| WBsf977296 | |||||||||
| WBsf977297 | |||||||||
| WBsf1020480 | |||||||||
| WBsf232532 | |||||||||
| Experimental_info | RNAi_result (19) | ||||||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00037630 | ||||||||
| Construct_product | WBCnstr00037630 | ||||||||
| Regulate_expr_cluster | WBPaper00045565:BIR-1_induced | ||||||||
| WBPaper00045565:BIR-1_suppressed | |||||||||
| Antibody | WBAntibody00000302 | ||||||||
| WBAntibody00002920 | |||||||||
| WBAntibody00002966 | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (136) | |||||||||
| Interaction | WBInteraction000003715 | ||||||||
| WBInteraction000003716 | |||||||||
| WBInteraction000003717 | |||||||||
| WBInteraction000003718 | |||||||||
| WBInteraction000003953 | |||||||||
| WBInteraction000009667 | |||||||||
| WBInteraction000028557 | |||||||||
| WBInteraction000028699 | |||||||||
| WBInteraction000028769 | |||||||||
| WBInteraction000028825 | |||||||||
| WBInteraction000028837 | |||||||||
| WBInteraction000028876 | |||||||||
| WBInteraction000029436 | |||||||||
| WBInteraction000029437 | |||||||||
| WBInteraction000029444 | |||||||||
| WBInteraction000029979 | |||||||||
| WBInteraction000029980 | |||||||||
| WBInteraction000029981 | |||||||||
| WBInteraction000029982 | |||||||||
| WBInteraction000029983 | |||||||||
| WBInteraction000029984 | |||||||||
| WBInteraction000029985 | |||||||||
| WBInteraction000029986 | |||||||||
| WBInteraction000121204 | |||||||||
| WBInteraction000126982 | |||||||||
| WBInteraction000138004 | |||||||||
| WBInteraction000138005 | |||||||||
| WBInteraction000143148 | |||||||||
| WBInteraction000147191 | |||||||||
| WBInteraction000165679 | |||||||||
| WBInteraction000165779 | |||||||||
| WBInteraction000165854 | |||||||||
| WBInteraction000165857 | |||||||||
| WBInteraction000384088 | |||||||||
| WBInteraction000384258 | |||||||||
| WBInteraction000401401 | |||||||||
| WBInteraction000501681 | |||||||||
| WBInteraction000501682 | |||||||||
| WBInteraction000506874 | |||||||||
| WBInteraction000512551 | |||||||||
| WBInteraction000512552 | |||||||||
| WBInteraction000512555 | |||||||||
| WBInteraction000512556 | |||||||||
| WBInteraction000512558 | |||||||||
| WBInteraction000512559 | |||||||||
| WBInteraction000512560 | |||||||||
| WBInteraction000512563 | |||||||||
| WBInteraction000512566 | |||||||||
| WBInteraction000512568 | |||||||||
| WBInteraction000515187 | |||||||||
| WBInteraction000515188 | |||||||||
| WBInteraction000515189 | |||||||||
| WBInteraction000521555 | |||||||||
| WBInteraction000522361 | |||||||||
| WBInteraction000522362 | |||||||||
| WBInteraction000522364 | |||||||||
| WBInteraction000522367 | |||||||||
| WBInteraction000522887 | |||||||||
| WBInteraction000522888 | |||||||||
| WBInteraction000522889 | |||||||||
| WBInteraction000527386 | |||||||||
| WBInteraction000539530 | |||||||||
| WBInteraction000539531 | |||||||||
| WBInteraction000539532 | |||||||||
| WBInteraction000539533 | |||||||||
| WBInteraction000539534 | |||||||||
| WBInteraction000539535 | |||||||||
| WBInteraction000539536 | |||||||||
| WBInteraction000539537 | |||||||||
| WBInteraction000539538 | |||||||||
| WBInteraction000539539 | |||||||||
| WBInteraction000542495 | |||||||||
| WBInteraction000558109 | |||||||||
| WBInteraction000558112 | |||||||||
| WBInteraction000558113 | |||||||||
| WBInteraction000558114 | |||||||||
| WBInteraction000558115 | |||||||||
| WBInteraction000558116 | |||||||||
| WBInteraction000558117 | |||||||||
| WBInteraction000558120 | |||||||||
| WBInteraction000558122 | |||||||||
| WBInteraction000558125 | |||||||||
| Map_info | Map | V | Position | 3.22936 | Error | 0.001138 | |||
| Positive | Positive_clone | T27F2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4169 | |||||||
| 5515 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (32) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
