| WBGene00020112 | SMap | S_parent | Sequence | R151 |
|---|
| Identity | Version | 2 |
| | Name | CGC_name | pfd-5 | Person_evidence | WBPerson3663 |
| | | | | | WBPerson2136 |
| | | Sequence_name | R151.9 |
| | | Molecular_name | R151.9 |
| | | | R151.9.1 |
| | | | CE00827 |
| | | Other_name | 3H288 | Accession_evidence | EMBL | AF303258 |
| | | | CELE_R151.9 | Accession_evidence | NDB | BX284603 |
| | | Public_name | pfd-5 |
| | DB_info | Database | AceView | gene | 3I288 |
| | | | WormQTL | gene | WBGene00020112 |
| | | | WormFlux | gene | WBGene00020112 |
| | | | NDB | locus_tag | CELE_R151.9 |
| | | | Panther | gene | CAEEL|WormBase=WBGene00020112|UniProtKB=Q21993 |
| | | | | family | PTHR12674 |
| | | | NCBI | gene | 176013 |
| | | | RefSeq | protein | NM_066181.6 |
| | | | SwissProt | UniProtAcc | Q21993 |
| | | | TREEFAM | TREEFAM_ID | TF106509 |
| | | | UniProt_GCRP | UniProtAcc | Q21993 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 28 May 2004 13:31:02 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 |
| | | | 2 | 02 Aug 2006 11:39:27 | WBPerson2970 | Name_change | CGC_name | pfd-5 |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | pfd |
| | Allele | WBVar00837961 |
| | | WBVar00837962 |
| | | WBVar00837963 |
| | | WBVar00837964 |
| | | WBVar00837965 |
| | | WBVar00837966 |
| | | WBVar00837967 |
| | | WBVar01500260 |
| | | WBVar01541819 |
| | | WBVar00401256 |
| | | WBVar00059560 |
| | | WBVar00146030 |
| | | WBVar01499774 |
| | | WBVar01837779 |
| | | WBVar01667472 |
| | | WBVar01628722 |
| | | WBVar01446575 |
| | | WBVar01722860 |
| | | WBVar01722861 |
| | Strain | WBStrain00001158 |
| | | WBStrain00036684 |
| | RNASeq_FPKM (74) |
| | GO_annotation | 00073616 |
| | | 00073617 |
| | | 00073618 |
| | | 00073619 |
| | | 00073620 |
| | | 00124826 |
| | | 00124827 |
| | | 00124828 |
| | Contained_in_operon | CEOP3420 |
| | Ortholog (31) |
| | Paralog | WBGene00018071 | Caenorhabditis elegans | From_analysis | Panther |
| | Structured_description | Concise_description | pfd-5 encodes a putative prefoldin 5 subunit, orthologous to human PFDN5 (OMIM:604899), that is required for normal microtubule growth, embryonic and larval viability, fertility, vulval development, and locomotion; PFD-5 is expressed in most, if not all, tissues; pfd-5(RNAi) animals show sterile progeny, larval arrest or lethality, uncoordination, and abnormal body shapes, and pfd-5(RNAi) embryos show a reduced microtubule growth rate. | Paper_evidence | WBPaper00004403 |
| | | | | | WBPaper00005654 |
| | | | | | WBPaper00006395 |
| | | | | | WBPaper00024497 |
| | | | | | WBPaper00025054 |
| | | | | | WBPaper00031309 |
| | | | | | WBPaper00031362 |
| | | | | | WBPaper00031363 |
| | | | | Curator_confirmed | WBPerson567 |
| | | | | Date_last_updated | 14 Jan 2008 00:00:00 |
| | | Automated_description | Predicted to enable unfolded protein binding activity. Predicted to be involved in RNA polymerase I assembly; RNA polymerase II core complex assembly; and RNA polymerase III assembly. Predicted to be located in cytoplasm. Predicted to be part of prefoldin complex. Expressed in body wall musculature; head muscle; pharyngeal muscle cell; and vulval muscle. Is an ortholog of human PFDN5 (prefoldin subunit 5). | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | R151.9 |
| | Corresponding_transcript | R151.9.1 |
| | Other_sequence (24) |
| | Associated_feature | WBsf651181 |
| | | WBsf666471 |
| | | WBsf226932 |
| Experimental_info | RNAi_result | WBRNAi00067299 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00002818 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00026126 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00051983 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00067873 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00002660 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00009079 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00034943 | Inferred_automatically | RNAi_primary |
| | Expr_pattern | Expr7840 |
| | | Expr1025899 |
| | | Expr1038748 |
| | | Expr1155625 |
| | | Expr2014845 |
| | | Expr2033080 |
| | Drives_construct | WBCnstr00002050 |
| | | WBCnstr00025366 |
| | Construct_product | WBCnstr00025366 |
| | Microarray_results (19) |
| | Expression_cluster | WBPaper00031040:TGF-beta_adult_downregulated |
| | | WBPaper00032528:L3_enriched |
| | | WBPaper00033065:cyc-1(RNAi)_upregulated |
| | | WBPaper00037047:insoluble_protein |
| | | WBPaper00037950:BAG-neuron_blastula-embryo_expressed |
| | | WBPaper00037950:bodywall-muscle_L2-larva_expressed |
| | | WBPaper00037950:CEP-sheath-cells_adult_enriched |
| | | WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed |
| | | WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed |
| | | WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed |
| | | WBPaper00037950:hypodermis_L3-L4-larva_expressed |
| | | WBPaper00037950:intestine_L1-larva_expressed |
| | | WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed |
| | | WBPaper00042477:rsr-2(RNAi)_downregulated_RNAseq |
| | | WBPaper00043951:Nascent-polypeptide-associated |
| | | WBPaper00044501:gld-1_let-7_regulated |
| | | WBPaper00044656:tatn-1(qd182)_downregulated |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00045316:prg-1_downregulated_L2 |
| | | WBPaper00045316:prg-1_downregulated_L3 |
| | | WBPaper00045521:Gender_Neutral |
| | | WBPaper00045565:BIR-1_suppressed |
| | | WBPaper00045571:germline-ablation_downregulated |
| | | WBPaper00045774:clk-1_downregulated |
| | | WBPaper00046012:tdp-1(ok803)_upregulated |
| | | WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h |
| | | WBPaper00046509:htz-1(ok3099)_downregulated |
| | | WBPaper00046509:lin-35(n745)_downregulated |
| | | WBPaper00048910:mRNA-interacting_protein |
| | | WBPaper00048926:miaserin_upregulated_adult-day5 |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi) |
| | | WBPaper00049942:hsf-1(RNAi)_downregulated |
| | | WBPaper00050344:ASER-neuron_enriched |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050686:glp-1(e2141)_downregulated |
| | | WBPaper00050990:arcade_intestinal-valve_expressed |
| | | WBPaper00050990:GABAergic-neuron_expressed |
| | | WBPaper00050990:hypodermis_expressed |
| | | WBPaper00050990:intestine_expressed |
| | | WBPaper00050990:NMDA-neuron_expressed |
| | | WBPaper00050990:pharynx_expressed |
| | | WBPaper00051039:germline_enriched |
| | | WBPaper00051245:body-wall-muscle_cytoplasm_expressed |
| | | WBPaper00051245:cytoplasm_specific |
| | | WBPaper00051245:epidermis_cytoplasm_expressed |
| | | WBPaper00051245:intestine_cytoplasm_expressed |
| | | WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed |
| | | WBPaper00051558:aging_regulated |
| | | WBPaper00053184:sma-2(rax5)_downregulated |
| | | WBPaper00053184:sma-4(rax3)_downregulated |
| | | WBPaper00053289:DREAM-target |
| | | WBPaper00053388:dauer_regulated_Cluster2 |
| | | WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated |
| | | WBPaper00053810:daf-2(e1370)_downregulated |
| | | WBPaper00053810:isp-1(qm150)_downregulated |
| | | WBPaper00055354:Rifampicin-Allantoin_upregulated |
| | | WBPaper00055648:germline_expressed |
| | | WBPaper00056034:pals-22(jy3)_downregulated |
| | | WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047) |
| | | WBPaper00056090:E.faecalis_downregulated_N2 |
| | | WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated |
| | | WBPaper00056471:S.aureus-4h_downregulated_N2 |
| | | WBPaper00056826:SGP_biased |
| | | WBPaper00057288:Cold_downregulated_protein |
| | | WBPaper00058691:sin-3(tm1276)_downregulated |
| | | WBPaper00059356:BAZ-2_SET-6_interacting |
| | | WBPaper00060014:set-2(zr2012)_upregulated |
| | | WBPaper00060100:SiNP_downregulated_mRNA |
| | | WBPaper00061274:hypergravity_15xg_downregulated |
| | | WBPaper00061340:ALM_BDU |
| | | WBPaper00061340:ALM_PLM |
| | | WBPaper00061341:28C_48h_downregulated |
| | | WBPaper00061390:daf-22(ok693)_ascarosides_downregulated |
| | | WBPaper00061479:HDA-1_interacting_protein |
| | | WBPaper00061527:snr-6-lsm-3 |
| | | WBPaper00062159:hda-2(ok1479)_downregulated |
| | | WBPaper00062669:extracellular-vesicle_protein |
| | | WBPaper00064005:starvation_upregulated_aptf-1(gk794)_mRNA |
| | | WBPaper00064005:starvation_upregulated_N2_mRNA |
| | | WBPaper00064071:NHR-49_interacting |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated |
| | | WBPaper00064716:paraquat_upregulated |
| | | WBPaper00064933:E.coli-binding_secret_protein |
| | | WBPaper00065993:glp-1(e2141)_downregulated |
| | | WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14 |
| | | cgc4386_cluster_5_3 |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00025141:unc-4::GFP_Expressed_Genes |
| | | WBPaper00026929:sir-2.1_overexpression_regulated |
| | | WBPaper00026980:intestine_enriched |
| | | WBPaper00031532:Larva_Pan_Neuronal_Enriched |
| | | WBPaper00032165:differentially_expressed_with_age_medoid_6 |
| | | WBPaper00036375:depleted_in_PVD_OLL |
| | | WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2down |
| | | WBPaper00040858:eQTL_age_regulated_aging |
| | | WBPaper00041606:CE_X.nematophila_regulated |
| | | WBPaper00045263:nuo-6(qm200)_downregulated |
| | | WBPaper00053236:Starvation_regulated_GR1307 |
| | | WBPaper00053236:Starvation_regulated_N2 |
| | | [cgc5767]:expression_class_E |
| | | [cgc5767]:expression_class_ET |
| | | [cgc5767]:expression_class_ET_max(101_min) |
| | | [cgc5767]:expression_class_E_pi(53_min) |
| | | [cgc5767]:expression_class_E_pi(66_min) |
| | | [cgc5767]:expression_class_M |
| | | [cgc5767]:expression_class_ME |
| | | [cgc5767]:expression_class_MET |
| | Interaction (91) |
| Map_info | Map | III | Position | -0.772 |
| | Positive | Positive_clone | R151 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Pseudo_map_position |
| Reference | WBPaper00031309 |
| | WBPaper00038491 |
| | WBPaper00049828 |
| | WBPaper00055090 |
| | WBPaper00057218 |
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission |
| | [200811 gw3] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (-0.772512) |
| | [200811 gw3] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (-0.769642) |
| Method | Gene |
