WormBase Tree Display for Gene: WBGene00019404

WBGene00019404 SMap: S_parent: Sequence: K05B2
  Identity: Version: 1
    Name: Sequence_name: K05B2.4
      Molecular_name: K05B2.4
        K05B2.4.1
        CE47238
      Other_name: CELE_K05B2.4 Accession_evidence: NDB BX284606
      Public_name: K05B2.4
    DB_info: Database: AceView gene XF534
        WormQTL gene WBGene00019404
        WormFlux gene WBGene00019404
        NDB locus_tag CELE_K05B2.4
        Panther gene CAEEL|WormBase=WBGene00019404|UniProtKB=Q9GYN3
          family PTHR10824
        NCBI gene 187017
        RefSeq protein NM_076436.5
        TREEFAM TREEFAM_ID TF314911
        TrEMBL UniProtAcc Q9GYN3
        UniProt_GCRP UniProtAcc Q9GYN3
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:01 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele: WBVar01143841
      WBVar01143842
      WBVar01143843
      WBVar01143844
      WBVar01143845
      WBVar01143846
      WBVar01878521
      WBVar00255096
      WBVar01549512
      WBVar01549513
      WBVar01549514
      WBVar00502514
      WBVar00502515
      WBVar00502516
      WBVar00502517
      WBVar00502518
      WBVar00502519
      WBVar00502520
      WBVar00502521
      WBVar01819676
      WBVar01819677
      WBVar00078403
      WBVar00078404
      WBVar00078405
      WBVar00078406
      WBVar02139226
      WBVar00078407
      WBVar02139227
      WBVar00078408
      WBVar01500067
    RNASeq_FPKM (74)
    GO_annotation: 00092844
      00092845
      00092846
      00124253
      00124254
    Ortholog (49)
    Paralog: WBGene00007857 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00020258 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00020989 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid metabolic process. Human ortholog(s) of this gene implicated in disease of metabolism. Is an ortholog of several human genes including ACOT2 (acyl-CoA thioesterase 2); ACOT4 (acyl-CoA thioesterase 4); and BAAT (bile acid-CoA:amino acid N-acyltransferase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0014667 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:932)
  Molecular_info: Corresponding_CDS: K05B2.4
    Corresponding_CDS_history: K05B2.4:wp108
      K05B2.4:wp230
    Corresponding_transcript: K05B2.4.1
    Other_sequence: CR04198
      CRC06827_1
      EX916622.1
      EX912063.1
      CBC01294_1
    Associated_feature: WBsf1005121
      WBsf237334
  Experimental_info: RNAi_result: WBRNAi00092611 Inferred_automatically: RNAi_primary
      WBRNAi00049967 Inferred_automatically: RNAi_primary
      WBRNAi00016619 Inferred_automatically: RNAi_primary
      WBRNAi00033979 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1012837
      Expr1038379
      Expr1153663
      Expr2004783
      Expr2023006
    Drives_construct: WBCnstr00025863
    Construct_product: WBCnstr00025863
    Microarray_results (18)
    Expression_cluster: WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_embryo_enriched
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00040420:ALM_PLM_enriched
      WBPaper00040560:hpl-2_L3_downregulated
      WBPaper00041954:ethanol_upregulated
      WBPaper00042477:prp-8(RNAi)_downregulated_RNAseq
      WBPaper00042561:smg-2(RNAi)_upregulated
      WBPaper00044260:1-methylnicotinamide_upregulated
      WBPaper00044316:HgCl2_20uM_upregulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:flat_dev_expression
      WBPaper00044760:somatic_specific
      WBPaper00044857:BAR-1_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00049018:swsn-2.2(RNAi)_downregulated
      WBPaper00049290:rsks-1(sv31)_upregulated
      WBPaper00049334:CE_intestine_enriched
      WBPaper00049368:daf-2(e1370)_downregulated
      WBPaper00049498:npr-1(ur89)_regulated_5
      WBPaper00049732:blmp-1(tm548);daf-7(e1372ts)_vs_daf-7(e1372ts)_upregulated
      WBPaper00049920:hyl-2(tm2031)_upregulated
      WBPaper00050015:ifg-1(RNAi)_downregulated
      WBPaper00050080:rbr-2(tm3141)_upregulated
      WBPaper00050096:P.aeruginosa_upregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_100-cell-embryo
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050370:mys-1(RNAi)_L3_upregulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_adult_25C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050561:indole_10-fold_upregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050743:elli-1(sam-3)_upregulated
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00051021:4-bromodiphenyl-ether_upregulated
      WBPaper00051257:Levamisole_upregulated
      WBPaper00051265:F4_hrde-1(tm1200)_upregulated
      WBPaper00052856:Cadmium_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(ot267)_downregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053318:Aging_upregulated_mRNA_N2
      WBPaper00053318:mir-71(n4115)_upregulated_mRNA
      WBPaper00053771:up_at_3h-NaCl
      WBPaper00053798:nhr-49(nr2041)_tBOOH_upregulated
      WBPaper00053810:sod-2(ok1030)_upregulated
      WBPaper00053814:OP50_vs_PY79_downregulated_PY79
      WBPaper00054191:H3.3(null)_L1_downregulated
      WBPaper00054192:cold-shock_upregulated
      WBPaper00054410:set-26(tm2467)_upregulated
      WBPaper00054493:hpl-2(tm1489)_upregulated
      WBPaper00054758:alg-1(gk204)_upregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055354:Psora-Allantoin_upregulated
      WBPaper00055354:Psora_upregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055386:daf-2(e1370)_downregulated
      WBPaper00055386:eat-2(ad465)_downregulated
      WBPaper00055941:atfs-1(et15)_upregulated
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056167:Cry5B_downregulated
      WBPaper00056167:ifo-1(kc2)_downregulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056275:P.aeruginosa_upregulated_pmk-1(km25)_dependent
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056290:mdt-15(mg584)_upregulated
      WBPaper00056330:glycine_downregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056826:hmc_biased
      WBPaper00057196:raga-1(ok386)_upregulated)
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058711:wdr-5(ok1417)_upregulated
      WBPaper00058725:sftb-1(cer39)_downregulated
      WBPaper00058925:acox-1.1(ok2257)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00058969:RIS_depleted
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059191:hsp-16.2p-LIN-29_downregulated
      WBPaper00059334:sacy-1(depletion)_regulated
      WBPaper00059566:wdr-23(mac32)_upregulated
      WBPaper00059567:olrn-1(ums9)_regulated
      WBPaper00059604:fluvastatin_downregulated_dlk-1(km12)
      WBPaper00059604:fluvastatin_downregulated_N2
      WBPaper00059728:5ug_cholesterol_upregulated
      WBPaper00059728:20ug_cholesterol_upregulated
      WBPaper00059735:glucose_upregulated_lpin-1(RNAi)
      WBPaper00059754:P.aeruginosa_PA14_upregulated
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00059895:wounding_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_N2
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060434:pH4.33_vs_pH6.33_uprgulated
      WBPaper00060445:ikb-1(nr2027)_downregulated_L4
      WBPaper00060445:ikb-1(nr2027)_upregulated_L1
      WBPaper00060445:nfki-1(cer1)_downregulated_L4
      WBPaper00060526:plp-1(ok2155)_downregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060703:nas-38(ok3407)_upregulated
      WBPaper00060871:M.humicola-infection_48h_regulated
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00060909:atfs-1(et18)_upregulated
      WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061007:X.citri_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061319:pnp-1(jy90)_upregulated
      WBPaper00061340:Rectal_cell
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061357:mett-10(ok2204)_upregulated_OP50
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061527:chd-7_16664-jmjd-3.1
      WBPaper00061530:nhr-49(e2144)_downregulated
      WBPaper00061590:CGP37157_upregulated
      WBPaper00061653:alh-4(hj221)_upregulated
      WBPaper00062146:MOG-7-degron_2h_regulated
      WBPaper00062156:jmjd-1.2(zr1010)_upregulated
      WBPaper00062156:jmjd-5(zr1234)_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_upregulated_N2
      WBPaper00062345:bortezomib_4h_upregulated_zip-1(jy13)
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062354:H.zoospora_12h_regulated
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062606:rotenone_upregulated
      WBPaper00062672:dcp-66(RNAi)_upregulated
      WBPaper00062672:let-418(n3536)dcp-66(RNAi)_upregulated
      WBPaper00062672:let-418(n3536)_upregulated
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064196:ascaroside-10_downregulated_50h
      WBPaper00064509:static-magnetic-field_upregulated
      WBPaper00064532:pals-22(jy3)_downregulated
      WBPaper00064539:nhr-114(gk849)_upregulated
      WBPaper00064735:bet-1(RNAi)_vs_N2_upregulated
      WBPaper00064735:bet-1(uth41)_vs_N2_upregulated
      WBPaper00064871:PA14_upregulated_AWA
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065096:npr-8(ok1439)_downregulated_Day1_20C
      WBPaper00065225:nhr-42(tm1375)_upregulated_S.aureus-infected
      WBPaper00065288:mdt-15(tm2182)_downregulated
      WBPaper00065315:mating_upregulated_Day2-7
      WBPaper00065315:mating_upregulated_Day6-7
      WBPaper00065331:100nM-ivermectin_upregulated
      WBPaper00065746:eat-2(ad1113)_downregulated
      WBPaper00065749:endu-2(tm4977)_upregulated
      WBPaper00065749:Heat-Shock-With-Recovery_upregulated_N2
      WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977)
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065984:pals-17(syb3980)_downregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066110:Cisplatin_downregulated_diploid
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
      WBPaper00066232:hsf-1(RNAi)_upregulated_WT
      cgc4489_group_8
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00027111:rrf-3(pk1426)_downregulated
      WBPaper00028789:PA14_vs_gacA_upregulated_4hr
      WBPaper00028789:PA14_vs_OP50_upregulated_4hr
      WBPaper00028789:PA14_vs_OP50_upregulated_8hr
      WBPaper00029437:dcr-1_upregulated
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00032165:differentially_expressed_with_age_medoid_2
      WBPaper00032948:FedUp
      WBPaper00037695:WC_5-day
      WBPaper00038231:Cry5B_1.5-fold_upregulated
      WBPaper00038231:Cry5B_2-fold_upregulated
      WBPaper00038304:octr-1_regulated
      WBPaper00039792:TempShiftIncrease
      WBPaper00039851:HK_C_albicans_vs_HK_OP50
      WBPaper00039851:Live_C_albicans_vs_HK_OP50
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040876:mir-35_downregulated
      WBPaper00041211:RPW-24_Up
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041960:N2_fasting_upregulated_9hto12h
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00042067:Cu2+_upregulated_WT
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00044091:Bpseudomallei_induced_2h
      WBPaper00044091:Bpseudomallei_induced_8h
      WBPaper00044091:Bpseudomallei_induced_12h
      WBPaper00044535:male_upregulated
      WBPaper00045673:colistin_upregulated
      WBPaper00046083:ogt-1(ok1474)_OP50_downregulated
      WBPaper00046083:pmk-1(km25)_OP50_downregulated
      WBPaper00046548:dafachronic-acid_downregulated
      WBPaper00046853:AOBr_M.aeruginosa-batch-culture_upregulated
      WBPaper00047070:DAF-16-dependent_UV_response
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00051448:P.aeruginosa_Liquid-Killing_upregulated
      WBPaper00053688:E.faecalis_downregulated
      [cgc6390]:Cluster_C
    Interaction: WBInteraction000032305
      WBInteraction000343434
      WBInteraction000547445
      WBInteraction000549883
      WBInteraction000549916
      WBInteraction000549920
  Map_info: Positive: Positive_clone: K05B2 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: X -6.21535
  Reference: WBPaper00038491
    WBPaper00042257
    WBPaper00046514
    WBPaper00055090
    WBPaper00065331
  Method: Gene