WormBase Tree Display for Gene: WBGene00012977

WBGene00012977 SMap: S_parent: Sequence: Y48A6C
  Identity: Version: 1
    Name: Sequence_name: Y48A6C.4
      Molecular_name: Y48A6C.4
        Y48A6C.4.1
        CE43502
      Other_name: CELE_Y48A6C.4 Accession_evidence: NDB BX284603
      Public_name: Y48A6C.4
    DB_info: Database: AceView gene 3M213
        WormQTL gene WBGene00012977
        WormFlux gene WBGene00012977
        NDB locus_tag CELE_Y48A6C.4
        Panther gene CAEEL|WormBase=WBGene00012977|UniProtKB=Q9XWK5
          family PTHR16056
        NCBI gene 190016
        RefSeq protein NM_067032.4
        TREEFAM TREEFAM_ID TF318197
        TrEMBL UniProtAcc Q9XWK5
        UniProt_GCRP UniProtAcc Q9XWK5
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:54 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele: WBVar01500260
      WBVar01646129
      WBVar01497339
      WBVar01919076
      WBVar01334280
      WBVar01334281
      WBVar01919077
      WBVar01334288
      WBVar02121006
      WBVar01579005
      WBVar01507689
      WBVar01579006
      WBVar01507690
      WBVar01507691
      WBVar01269219
      WBVar01416483
      WBVar01269220
      WBVar01269221
      WBVar01269222
      WBVar01269223
      WBVar01269225
      WBVar01269226
      WBVar01480433
      WBVar00860663
      WBVar01480434
      WBVar02123231
      WBVar00860664
      WBVar00860665
      WBVar00860666
      WBVar00860667
      WBVar00860668
      WBVar00860669
      WBVar00860670
      WBVar00860671
      WBVar00860672
      WBVar00860673
      WBVar00860674
      WBVar00860675
      WBVar00860676
      WBVar00860677
      WBVar01498296
      WBVar00860678
      WBVar01910727
      WBVar00860679
      WBVar00860680
      WBVar00860681
      WBVar01499774
      WBVar00860682
      WBVar00860683
      WBVar00860684
      WBVar00860685
      WBVar00860686
      WBVar00860687
      WBVar02068636
      WBVar00860688
      WBVar00860689
      WBVar00860690
      WBVar02121418
      WBVar00860691
      WBVar00860692
      WBVar00860693
      WBVar00860694
      WBVar01817936
      WBVar00860695
      WBVar02111307
      WBVar01397516
      WBVar01397517
      WBVar00270033
      WBVar02122381
      WBVar02124961
      WBVar02124962
      WBVar02123680
      WBVar01657165
      WBVar00408770
      WBVar00408771
      WBVar00408772
      WBVar00408773
      WBVar00408774
      WBVar00179443
      WBVar00408775
      WBVar00179444
      WBVar00408776
      WBVar00179445
      WBVar00408777
      WBVar00179446
      WBVar00408778
      WBVar00408779
      WBVar00408780
      WBVar00408781
      WBVar01409517
      WBVar00408782
      WBVar00408783
      WBVar00408784
      WBVar00408785
      WBVar00408786
      WBVar00408787
    RNASeq_FPKM (74)
    GO_annotation: 00103625
      00103626
      00103627
      00103628
    Ortholog (33)
    Paralog: WBGene00007190 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00007786 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00009369 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00011501 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00012976 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00015855 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00020070 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: Y48A6C.4 encodes an ortholog of S. cerevisiae IPI1 that may suppress tumorous growth in the germ line by ensuring robust larval germline proliferation; like PRO-1, -2, and -3, Y48A6C.4 is probably required for ribosome biogenesis, suggesting a link between biogenesis in the distal sheath and control of cell division in the germ line. Paper_evidence: WBPaper00028280
            WBPaper00028929
          Curator_confirmed: WBPerson567
          Date_last_updated: 23 Apr 2008 00:00:00
      Automated_description: Predicted to be located in nucleus. Predicted to be part of MLL1 complex. Is an ortholog of human TEX10 (testis expressed 10). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y48A6C.4
    Corresponding_CDS_history: Y48A6C.4:wp200
    Corresponding_transcript: Y48A6C.4.1
    Other_sequence: GR978404.1
      Hbac_isotig02411
      JI174502.1
      CBC08125_1
      SC00846
      CJC09707_1
      HBC16354_1
      EX914738.1
    Associated_feature: WBsf645601
      WBsf994276
      WBsf994277
      WBsf1015929
      WBsf1015930
      WBsf225794
      WBsf225795
  Experimental_info: RNAi_result: WBRNAi00006365 Inferred_automatically: RNAi_primary
      WBRNAi00009350 Inferred_automatically: RNAi_primary
      WBRNAi00026750 Inferred_automatically: RNAi_primary
      WBRNAi00071666 Inferred_automatically: RNAi_primary
      WBRNAi00071364 Inferred_automatically: RNAi_primary
      WBRNAi00002637 Inferred_automatically: RNAi_primary
      WBRNAi00056871 Inferred_automatically: RNAi_primary
      WBRNAi00037226 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1021678
      Expr1035755
      Expr1160323
      Expr2007653
      Expr2025893
    Microarray_results (22)
    Expression_cluster: WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045774:clk-1_downregulated
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049498:npr-1(ur89)_regulated_6
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00050412:cco-1(RNAi)_upregulated_N2
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00051039:germline_enriched
      WBPaper00051265:F4_morc-1(tm6048)_upregulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00055334:DLC-1_interacting
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056284:ints-5(RNAi)_upregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059987:Wounding_downregulated
      WBPaper00061340:AIZ
      WBPaper00061340:B
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061466:nath-10(icb99)_downregulated
      WBPaper00061527:Y39G10AR.18_4775-gld-4
      WBPaper00061902:CAMT-1_interacting
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00064005:starvation_upregulated_N2_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064716:paraquat_upregulated
      WBPaper00064735:bet-1B(OE)mys-1(RNAi)_vs_mys-1(RNAi)_upregulated
      WBPaper00065749:Heat-Shock_upregulated_endu-2(tm4977)
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066110:Doxorubicin_downregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4489_group_7
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00037695:WC_5-day
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2down
      WBPaper00040210:Diazinon_24C_regulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00041002:HF_11d_0.2mM_Up
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_3h
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00045673:colistin_downregulated
      WBPaper00045960:L1-L4-lethargus_downregulated
      WBPaper00045960:L4-lethargus_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00056330:mrps-5(RNAi)_downregulated
    Interaction: WBInteraction000040356
      WBInteraction000044341
      WBInteraction000044345
      WBInteraction000044354
      WBInteraction000044359
      WBInteraction000046099
      WBInteraction000048561
      WBInteraction000240606
      WBInteraction000297044
  Map_info: Positive: Positive_clone: Y48A6C Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: III 6.07936
  Reference: WBPaper00028280
    WBPaper00038491
    WBPaper00055090
  Method: Gene