WormBase Tree Display for Gene: WBGene00007150

WBGene00007150 SMap: S_parent: Sequence: B0365
  Identity: Version: 2
    Name: CGC_name: acly-2 Person_evidence: WBPerson260
      Sequence_name: B0365.1
      Molecular_name: B0365.1
        B0365.1.1
        CE07719
      Other_name: CELE_B0365.1 Accession_evidence: NDB BX284605
      Public_name: acly-2
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:47 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 06 Jan 2012 13:49:20 WBPerson2970 Name_change: CGC_name: acly-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: acly
    Allele: WBVar01059303
      WBVar01059304
      WBVar01059305
      WBVar01059306
      WBVar01059307
      WBVar01059308
      WBVar01059309
      WBVar01059310
      WBVar01059311
      WBVar01059312
      WBVar01059313
      WBVar01059314
      WBVar01059315
      WBVar01059316
      WBVar01059317
      WBVar01498809
      WBVar01059318
      WBVar01059319
      WBVar01059320
      WBVar01059321
      WBVar01059322
      WBVar01059323
      WBVar01059324
      WBVar01059325
      WBVar01059326
      WBVar01059327
      WBVar01059328
      WBVar01059329
      WBVar01059330
      WBVar01059331
      WBVar01743845
      WBVar01868980
      WBVar01868981
      WBVar01868982
      WBVar02078706
      WBVar01808935
      WBVar00474214
      WBVar01808936
      WBVar00474215
      WBVar00474216
      WBVar00474217
      WBVar00474218
      WBVar00474219
      WBVar00474220
      WBVar00474221
      WBVar00474222
      WBVar00474223
      WBVar00474224
      WBVar00474225
      WBVar00317366
      WBVar02150245
      WBVar01500212
      WBVar01500213
      WBVar01499299
      WBVar02024451
      WBVar01499316
      WBVar01975198
    RNASeq_FPKM (74)
    GO_annotation (21)
    Ortholog (51)
    Paralog: WBGene00016995 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable ATP citrate synthase activity. Predicted to be involved in acetyl-CoA biosynthetic process and fatty acid biosynthetic process. Predicted to be located in cytosol. Is an ortholog of human ACLY (ATP citrate lyase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: B0365.1
    Corresponding_transcript: B0365.1.1
    Other_sequence (384)
    Associated_feature (12)
  Experimental_info: RNAi_result: WBRNAi00062090 Inferred_automatically: RNAi_primary
      WBRNAi00009730 Inferred_automatically: RNAi_primary
      WBRNAi00038982 Inferred_automatically: RNAi_primary
      WBRNAi00028107 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1014029
      Expr1033079
      Expr1143151
      Expr2009162
      Expr2027399
    Drives_construct: WBCnstr00033961
    Construct_product: WBCnstr00033961
    Microarray_results (20)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032097:CGH-1-associated-mRNA
      WBPaper00037047:aging_accelerated_insoluble_protein
      WBPaper00037047:insoluble_protein
      WBPaper00037086:biotin_regulated
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038289:oocyte_protein
      WBPaper00040446:insoluble_protein
      WBPaper00040560:hpl-2_L3_upregulated
      WBPaper00044037:eat-2_downregulated
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044746:aging_upregulated_Day5
      WBPaper00044746:aging_upregulated_HeatShock
      WBPaper00044760:germline_specific
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Oogenic
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00048690:gonad-male-biased
      WBPaper00048988:neuron_expressed
      WBPaper00049498:npr-1(ur89)_regulated_6
      WBPaper00049920:Glucose-Diet_downregulated_N2
      WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00049954:BPS_downregulated
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050522:mafr-1(tm6082)_downregulated
      WBPaper00050686:glp-1(e2141)_downregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:downregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051558:fog-2(q71)_regulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:stavudine_72h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:embryo-to-L1_upregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
      WBPaper00053321:PGCs_enriched_NuGen
      WBPaper00053388:dauer_regulated_Cluster3
      WBPaper00053615:SMO-1_target
      WBPaper00053713:Starvation-induced_postdauer_vs_control_downregulated
      WBPaper00053814:25C_downregulated_PY79
      WBPaper00055103:thoc-5(wy822)_downregulated
      WBPaper00055626:pry-1(mu38)_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056161:hermaphrodite_enriched_siRNA
      WBPaper00056293:rpl-5(0)-rpl-33(0)_downregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056826:hmc_biased
      WBPaper00057154:HeatShock_downregulated_mRNA
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00057288:iff-1(RNAi)_upregulated_protein
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:CFP-1_interacting_protein
      WBPaper00058691:set-2(bn129)_upregulated
      WBPaper00059027:neuron-synapses_enriched
      WBPaper00059328:mrps-5(RNAi)_upregulated_protein
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00060014:set-2(zr2012)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061274:hypergravity_10xg_upregulated
      WBPaper00061274:hypergravity_15xg_upregulated
      WBPaper00061340:AVB
      WBPaper00061340:F_U
      WBPaper00061340:hmc_and_homolog
      WBPaper00061340:PVQ_parent
      WBPaper00061340:RIV
      WBPaper00061340:SMB
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061478:SUMO-conjugated_protein
      WBPaper00061527:D2023.6-mut-14_16769
      WBPaper00061753:csr-1(tor159)_downregulated_25C
      WBPaper00062056:dpl-1(n2994)_downregulated
      WBPaper00062056:lin-15B(we23)_downregulated
      WBPaper00062056:lin-37(n758)_downregulated
      WBPaper00062123:DEPS-1_interacting
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062456:doxycycline_downregulated_CB4856_protein
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062590:Aging_downregulated_body-wall-muscle
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA
      WBPaper00064005:starvation_downregulated_N2_mRNA
      WBPaper00064055:trl-1(cas1077)_upregulated_non-starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated
      WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
      WBPaper00064505:tamoxifen_upregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00064735:bet-1(uth41)_vs_N2_downregulated
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065841:52_0
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4489_group_2
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00032165:A_to_C_transit_decreased
      WBPaper00032165:differentially_expressed_with_age_medoid_5
      WBPaper00032948:StarveUp3
      WBPaper00034739:N2lessDR1350
      WBPaper00035084:L1_enriched_AIN-2_IP
      WBPaper00035084:L3_enriched_AIN-2_IP
      WBPaper00035873:dpy-10_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036286:Pattern_B
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00040963:TA100_down
      WBPaper00040963:TA300_down
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048563:L1_DD_enriched
      WBPaper00049538:atfs-1(et18)_upregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_MD_pd(PC32)
      [cgc5767]:expression_class_SM
      [cgc5767]:expression_class_SMD
      [cgc6390]:Cluster_F
      [cgc6390]:oogenesis-enriched
    Interaction (89)
  Map_info: Map: V Position: 4.91268
    Positive: Positive_clone: B0365 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (3)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene