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WormBase Tree Display for Expression_cluster: WBPaper00035654:alpha-synuclein_regulated

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Name Class

WBPaper00035654:alpha-synuclein_regulatedDescriptionGenes that differentially expressed in WBPaper00035654Is1[aex-3
SpeciesCaenorhabditis elegans
AlgorithmTIGR Spotfinder software was used to filter unreliable spots based on Otsu's method algorithm and to convert good spots in microarray images to numerical form. Raw signal values were analyzed using mean centering to normalize signal values between channels. Signals from Alexa Fluor Dye Control probes were excluded from normalization process due their oversaturation leaving only probe intensities from C. elegans miRNAs to use in normalization. Signal intensity ratios were calculated for each signal pair yielding fold change values and p values for each miRNAs from the strain of investigation. A cutoff of 1.4 was used to detect modestly changing miRNAs.
ReferenceWBPaper00035654
Microarray_resultsGPL8200_cel-miR-50Fold change, 2.29, p_value: 0.00037
GPL8200_cel-miR-83Fold change, 1.88, p_value: 0.00412
GPL8200_cel-miR-58Fold change, 1.84, p_value: 0.0735
GPL8200_cel-miR-77Fold change, 1.80, p_value: 0.05325
GPL8200_cel-miR-238Fold change, 1.64, p_value: 0.03271
GPL8200_cel-miR-1Fold change, 0.70, p_value: 0.00737
GPL8200_cel-miR-48Fold change, 0.68, p_value: 0.03964
GPL8200_cel-miR-65Fold change, 0.65, p_value: 0.01087
GPL8200_cel-miR-64Fold change, 0.56, p_value: 0.00262
GPL8200_cel-miR-80Fold change, 0.56, p_value: 0.00384
GPL8200_cel-miR-84Fold change, 0.43, p_value: 0.04759
GPL8200_cel-let-7Fold change, 0.34, p_value: 0.00089
Attribute_ofMicroarray_experimentWBPaper00035654:alpha-synuclein-Is10_vs_N2_rep1
WBPaper00035654:alpha-synuclein-Is10_vs_N2_rep2
WBPaper00035654:alpha-synuclein-Is10_vs_N2_rep3
WBPaper00035654:alpha-synuclein-Is10_vs_N2_rep4
Associated_withLife_stageWBls:0000038