WormBase Tree Display for Expression_cluster: WBPaper00035654:alpha-synuclein_regulated
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WBPaper00035654:alpha-synuclein_regulated | Description | Genes that differentially expressed in WBPaper00035654Is1[aex-3 | |
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Species | Caenorhabditis elegans | ||
Algorithm | TIGR Spotfinder software was used to filter unreliable spots based on Otsu's method algorithm and to convert good spots in microarray images to numerical form. Raw signal values were analyzed using mean centering to normalize signal values between channels. Signals from Alexa Fluor Dye Control probes were excluded from normalization process due their oversaturation leaving only probe intensities from C. elegans miRNAs to use in normalization. Signal intensity ratios were calculated for each signal pair yielding fold change values and p values for each miRNAs from the strain of investigation. A cutoff of 1.4 was used to detect modestly changing miRNAs. | ||
Reference | WBPaper00035654 | ||
Microarray_results | GPL8200_cel-miR-50 | Fold change, 2.29, p_value: 0.00037 | |
GPL8200_cel-miR-83 | Fold change, 1.88, p_value: 0.00412 | ||
GPL8200_cel-miR-58 | Fold change, 1.84, p_value: 0.0735 | ||
GPL8200_cel-miR-77 | Fold change, 1.80, p_value: 0.05325 | ||
GPL8200_cel-miR-238 | Fold change, 1.64, p_value: 0.03271 | ||
GPL8200_cel-miR-1 | Fold change, 0.70, p_value: 0.00737 | ||
GPL8200_cel-miR-48 | Fold change, 0.68, p_value: 0.03964 | ||
GPL8200_cel-miR-65 | Fold change, 0.65, p_value: 0.01087 | ||
GPL8200_cel-miR-64 | Fold change, 0.56, p_value: 0.00262 | ||
GPL8200_cel-miR-80 | Fold change, 0.56, p_value: 0.00384 | ||
GPL8200_cel-miR-84 | Fold change, 0.43, p_value: 0.04759 | ||
GPL8200_cel-let-7 | Fold change, 0.34, p_value: 0.00089 | ||
Attribute_of | Microarray_experiment | WBPaper00035654:alpha-synuclein-Is10_vs_N2_rep1 | |
WBPaper00035654:alpha-synuclein-Is10_vs_N2_rep2 | |||
WBPaper00035654:alpha-synuclein-Is10_vs_N2_rep3 | |||
WBPaper00035654:alpha-synuclein-Is10_vs_N2_rep4 | |||
Associated_with | Life_stage | WBls:0000038 |