WormBase Tree Display for Expr_pattern: Expr8720
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| Expr8720 | Expression_of | Gene | WBGene00000843 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00000843 | ||
| Expression_data | GO_term | GO:0005768 | |
| GO:0005783 | |||
| GO:0043229 | |||
| Subcellular_localization | In wild-type coelomocytes, CUP-2::GFP colocalizes extensively with the smooth ER marker cytochrome b5 and the rough ER marker TRAM, indicating that at steady state, the majority of CUP-2 molecules reside in the ER. However, in addition to the ER staining, authors consistently detected CUP-2::GFP, but not the other ER markers, in peripheral organelles, suggesting that CUP-2 localizes to other compartments besides the ER. This peripheral staining was not of the Golgi complex that was visualized as discrete centralized puncta in coelomocytes. At least a portion of the peripheral CUP-2 staining was endosomal because it appeared to colocalize with RAB-5, although the elaborate nature of the ER in coelomocytes precludes an unambiguous determination. | ||
| Type | Reporter_gene | ||
| Picture | WBPicture0000009098 | ||
| Remark | Picture: Fig. 5D. | ||
| Reference | WBPaper00033458 | ||
| Transgene | WBTransgene00030671 |
