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WormBase Tree Display for Expr_pattern: Expr716

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Name Class

Expr716Expression_ofGeneWBGene00004729
Reflects_endogenous_expression_ofWBGene00004729
Expression_dataLife_stageWBls:0000024
WBls:0000038
WBls:0000027
WBls:0000035
WBls:0000041
WBls:0000020
WBls:0000017
WBls:0000010
Anatomy_termWBbt:0003679
WBbt:0003865
WBbt:0003866
WBbt:0003867
WBbt:0003868
WBbt:0003869
WBbt:0003870
WBbt:0003955
WBbt:0004074
WBbt:0004076
WBbt:0004092
WBbt:0004094
WBbt:0004431
WBbt:0004437
WBbt:0004438
WBbt:0004439
WBbt:0004757
WBbt:0004758
WBbt:0004969
WBbt:0004970
WBbt:0004971
WBbt:0004972
WBbt:0004977
WBbt:0004978
WBbt:0004979
WBbt:0004981
WBbt:0004983
WBbt:0004985
WBbt:0004987
WBbt:0004989
WBbt:0005013
WBbt:0005017
WBbt:0005033
WBbt:0005037
WBbt:0005733
WBbt:0005813Certain
TypeReporter_gene
PatternExpression observed in most or all neurons at high levels as well as in some hypodermal and muscle cells. In most neurons, sax-3::GFP expression is transient, peaking during the period of axon outgrowth. Highest level of expression is observed in the embryo, particularly during the initial period of axon outgrowth at 350-400 min (comma-stage). At comma-stage high level of expression is observed in anterior embryo, including most developing neurons of the nerve ring and a swath of ventral cells that includes the developing motor neurons of the ventral nerve cord and posterior neurons such as PVQ. Lower level of expression is observed in the epidermal cells. 200-400 - cell stage; 200-300 min of development: Expression seen in all epidermal cells at low level. 3-fold stage; >500 min of development: Expression seen in muscles that extend from nerve ring to the anterior tip of the head. L1: Expression in motor neurons in the head including RMD, RMG, SMD, SIA and SIB neurons; projection interneurons in the head and tail, including AVA, AVB, PVC, AVD, PVQ and ALA neurons; and the sensory OLQ neuron. This neuronal expression diminishes throughout postembryonic development. During L1, expression persists in the head muscles and appears in muscles along the body wall, with ventral muscles expressing more strongly than posterior muscles. This expression continues until the adult stage. Epidermal expression was rarely seen in larval stages. L2: Expression observed in HSN motor neurons. HSN motor neurons extends a growth cone (axon from their lateral cell bodies) towards the ventral midline and expression is at its highest at this point. L3: Expression observed in the axon reaching the ventral nerve cord. L4: Expression continues in HSN, when HSN axon grows anteriorly to the head. Adult: Expression decreases in HSN at this stage after the completion of HSN axon outgrowth. In addition expression observed in motor neurons, interneurons and sensory neurons listed above also postembryonic ventral cord motorneurons, some interneurons from the tail and head, body wall and vulval muscles.
PictureWBPicture0000009511
RemarkThis information was extracted from published material (Archana Sharma-Oates, Andrew Mounsey and Ian A. Hope).
ReferenceWBPaper00002997
TransgeneWBTransgene00029708