WormBase Tree Display for Expr_pattern: Expr600
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| Expr600 | Expression_of (2) | ||
|---|---|---|---|
| Expression_data (2) | |||
| Type | Antibody | Synthetic peptide corresponding to carboxyl terminus of CDC-25.1 protein. | |
| Pattern | Detected in nuclei of oocytes and the nuclei and cell cortex of early embryos. Diffuse in pachytene nuclei of distal gonad but more apparent in diakinetic nuclei of oocytes in proximal gonad arm. Cytoplasmic staining in older oocytes but lost once fertilized. After fertilization and completion of meiosis, staining observed in both oocyte and sperm pronuclei. Nuclear staining seen during pronuclear migration and meeting. Diffuse cytoplasmic labeling observed during the first mitotic cleavage. Staining seen in nuclei of 2 and 4-cell embryo. Staining persists until 24-28 cell stage, only in embryonic nuclei during interphase and prophase, diffuse cytoplasmic staining seen when nuclear envelop breakdown occurs after entry into M phase. The antibody localized specifically to cortical membrane between neighbouring blastomeres during all phases of cell cycle. | ||
| Remark (2) | |||
| Reference | WBPaper00003402 | ||
| Antibody_info | WBAntibody00000212 |
