WormBase Tree Display for Expr_pattern: Expr4766
expand all nodes | collapse all nodes | view schema
| Expr4766 | Expression_of | Gene | WBGene00000501 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00000501 | ||
| Expression_data | Life_stage | WBls:0000024 | |
| WBls:0000003 | |||
| WBls:0000038 | |||
| WBls:0000027 | |||
| WBls:0000035 | |||
| WBls:0000041 | |||
| GO_term | GO:0045202 | ||
| GO:0043005 | |||
| GO:0043025 | |||
| Subcellular_localization | Animals expressing this fusion protein were stained with anti-GFP and anti-UNC-17 (VAChT) Abs.Confocal microscopy revealed that CHO-1::GFP is present at most cholinergic synapses, beginning during embryogenesis, and persisting throughout development. CHO-1::GFP fluorescence was also observed in the neuronal cell bodies. In neuronal processes, the CHO-1::GFP was localized near cholinergic synaptic vesicles as indicated by anti-UNC-17 staining, but CHO-1 and UNC-17 did not fully co-localize, consistent with a plasma membrane localization of CHO-1. Thus a significant fraction of synaptically localized CHO-1 is not physically associated with cholinergic synaptic vesicles. | ||
| Type | Reporter_gene | ||
| Picture | WBPicture0000010968 | ||
| Reference | WBPaper00030822 | ||
| Transgene | WBTransgene00029441 |
