WormBase Tree Display for Expr_pattern: Expr3839
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| Expr3839 | Expression_of | Gene | WBGene00018285 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00018285 | |||
| Expression_data | Anatomy_term | WBbt:0005733 | Partial | |
| WBbt:0005772 | Certain | |||
| WBbt:0006751 | Partial | |||
| WBbt:0006759 | Partial | |||
| GO_term | GO:0005634 | |||
| Subcellular_localization | Expressed in nuclei. | |||
| Type | Reporter_gene | |||
| Pattern | Using a gfp-tagged smk-1 cDNA construct under the control of the endogenous smk-1 promoter to create a stable transgenic line, strong nuclear localization of SMK-1-GFP was observed in intestinal cells. GFP fluorescence was also detected in the nuclei of several hypodermal cells and in many neurons in the head and tail. | |||
| Picture | WBPicture0000009397 | |||
| Remark | The GFP signal was reduced upon treatment with smk-1 RNAi, and Western blot analysis showed that SMK-1 protein levels were reduced upon smk-1 RNAi treatment. | |||
| Reference | WBPaper00027157 | |||
| Transgene | WBTransgene00028906 |
