WormBase Tree Display for Expr_pattern: Expr2861
expand all nodes | collapse all nodes | view schema
| Expr2861 | Expression_of | Gene | WBGene00000901 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00000901 | |||
| Expression_data | Anatomy_term | WBbt:0003953 | Uncertain | |
| WBbt:0003954 | Uncertain | |||
| WBbt:0004491 | ||||
| WBbt:0004493 | ||||
| WBbt:0005451 | Certain | |||
| WBbt:0006751 | Certain | |||
| WBbt:0006759 | Certain | |||
| Type | Reporter_gene | |||
| Pattern | GFP expression was observed consistently in neurons in the head (including many amphid neurons and several unidentified cells located more anteriorly) and in neurons in the tail. W01G7.1/daf-5 is not expressed in ASI. The most frequently observed neuron pair in the tail has been tentatively identified as the left and right LUA interneurons based on the extent and direction of infrequently observed cell processes. Faint expression was occasionally observed in two other neurons in the tail. W01G7.1/daf-5 expression was also observed in the pharynx, most frequently in muscles in the anterior region (procorpus), but occasionally also in the isthmus and terminal bulb. Less frequently, expression in one or two cells located in the midbody was observed. By position, these could be ALML/R (touch-sensitive neurons), but no processes were observed. | |||
| Picture | WBPicture0000010091 | |||
| Remark | Expression of the W01G7.1/daf-5::GFP transgene overlaps partially with that of the gene encoding its two-hybrid binding partner, DAF-3/SMAD4, and with that of daf-1/TGF-beta-RI and daf-4/TGF-beta-RII. The overlap of W01G7.1/daf-5 and daf-3/SMAD4 expression occurs primarily in neurons in the head and in the pharynx (where W01G7.1/daf-5 expression is stronger). Unlike daf-3/SMAD4, W01G7.1/daf-5 is not expressed in the ventral cord, intestine, hypodermal cells, or gonadal distal tip cells. Cells in which W01G7.1/daf-5 and daf-1/TGF-beta-RI or W01G7.1/daf-5 and daf-4/TGF-beta-RII are expressed are confined to neurons in the head. W01G7.1/daf-5, daf-3/SMAD4, and daf-4/TGF-beta-RII are expressed in the pharynx whereas daf-1/TGF-beta-RI is not. daf-3/SMAD4 and daf-4/TGF-beta-RII are expressed in hypodermal cells; W01G7.1/daf-5 and daf-1/TGF-beta-RI are not. W01G7.1/daf-5 and daf-3/SMAD4, as well as daf-1/TGF-beta-RI, are expressed in midstage embryos, all larval stages, and the adult. | |||
| Reporter gene fusion type not specified. | ||||
| Reference | WBPaper00006425 | |||
| Transgene | WBTransgene00001000 | |||
| WBTransgene00001001 |
