WormBase Tree Display for Expr_pattern: Expr2809

Expr2809 Expression_of: Gene: WBGene00001365
    Reflects_endogenous_expression_of: WBGene00001365
  Expression_data: Anatomy_term: WBbt:0005451 Certain
      WBbt:0005733 Certain
      WBbt:0005736 Certain
      WBbt:0005799 Certain
      WBbt:0005800 Certain
      WBbt:0006748 Certain
      WBbt:0006754 Certain
    GO_term: GO:0016324
      GO:0005887
      GO:0043296
  Subcellular_localization: In the excretory system, EXC-4 localizes to the lumenal membrane of the excretory cell, the duct, and the pore cell. Apical lumenal localization is also observed in the tubeforming cells generating the anus. In the lateral seam cells of the hypodermis, EXC-4 localizes directly adjacent to the adherens junction marker AJM-1 to a compact subapical belt of plasma membrane called the apical junction. In phasmid and labial sheath cells, EXC-4 selectively localizes to the extreme tip of the sheath cell membranes, which enwrap the dendritic ending of sensory neurons and fuse with themselves to form an elongated tubular structure exposed to the sensory environment.
  Type: Reporter_gene
  Pattern: The gfp-tagged genomic exc-4 locus, which is capable of rescuing the exc-4 mutant phenotype, shows expression in the excretory system, hypodermis, vulva, pharyngeal muscle, rectal gland, tubular rectal epithelial cells, and tubular neuronal support cells in the head and tail. EXC-4 protein showed highly specific patterns of subcellular localization. Taken together, EXC-4 localizes to very distinct membranes that undergo substantial remodeling (growth and fusion) in order to create diverse, often tubular membrane structures. EXC-4 localizes in amphid sheath cells in the head and epithelial cells in the anus.
  Picture: WBPicture0000010701
    WBPicture0000010702
  Reference: WBPaper00006263
  Transgene: WBTransgene00028188