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| WBPicture0000010702 | Description | Figure 3. Determinants of apical membrane localization of the EXC-4 protein. (A) GFP reporter fusion constructs (7). alpha helix 1 (orange) and beta sheets 2 (blue) are indicated within the exons (boxes). (B) EXC-4::GFP reporter fusion localization in transgenic animals. n, excretory cell nucleus; l, intralumenal space; L, left; P, posterior; R, right; A, anterior. Dashed lines show approximate location of the excretory cell perimeter. For all mutant proteins, localization was assessed both in wild-type and in exc-4(rh133) mutant backgrounds to eliminate a potential contribution of wild-type channel proteins to the localization of the GFP construct. Expression levels of most of the mutant exc-4::gfp reporters are down-regulated compared with wild-type protein. | |||
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| Name | F3.large.jpg | ||||
| Depict | Expr_pattern | Expr2809 | |||
| Anatomy | WBbt:0005812 | ||||
| Acknowledgment | Template | From <Article_URL>. Reprinted with permission from <Publisher_URL>. Readers may view, browse, and/or download material for temporary copying purposes only, provided these uses are for noncommercial personal purposes. Except as provided by law, this material may not be further reproduced, distributed, transmitted, modified, adapted, performed, displayed, published, or sold in whole or in part, without prior written permission from the publisher. | |||
| Publication_year | 2003 | ||||
| Article_URL | DOI | id | 10.1126/science.1087667 | ||
| Journal_URL | Science | ||||
| Publisher_URL | AAAS | ||||
| Reference | WBPaper00006263 |
