WormBase Tree Display for Expr_pattern: Expr1859
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Expr1859 | Expression_of | Gene | WBGene00003367 |
---|---|---|---|
Reflects_endogenous_expression_of | WBGene00003367 | ||
Expression_data | GO_term | GO:0000793 | |
Subcellular_localization | The mitotic localization pattern of MIX-1 was identical to that of SMC-4 throughout the cell cycle. SMC-4 and MIX-1 were both absent from decondensed chromosomes and coincident on condensed chromosomes. During metaphase, MIX-1 and SMC-4 decorated the chromosomes in the same distinctive poleward pattern. Unlike MIX-1, however, SMC-4 did not localize to hermaphrodite X chromosomes. The wild-type larva contains two mitotic cells brightly stained by both MIX-1 and SMC-4, but only MIX-1 shows the punctate nuclear staining characteristic of dosage compensation proteins bound to X chromosomes. See Expr1858 for SMC-4 expression pattern. | ||
Type | Antibody | Two different MIX-1 antibodies showed the same immunoprecipitation and immunostaining results. Most experiments used the carboxy-terminal peptide antibody provided by R. Chan against a carboxy-terminal peptide of MIX-1. | |
Picture | WBPicture0000008428 | ||
Remark | No detailed description on cellular expression patterns. | ||
Reference | WBPaper00005173 | ||
Antibody_info | WBAntibody00000480 |