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WormBase Tree Display for Expr_pattern: Expr1820

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Name Class

Expr1820Expression_ofGeneWBGene00003917
Reflects_endogenous_expression_ofWBGene00003917
Expression_dataLife_stageWBls:0000005
Anatomy_termWBbt:0005906
WBbt:0005994
WBbt:0006874
WBbt:0006876
GO_termGO:0016323
Subcellular_localizationBy the 4-cell stage, the posterior PAR protein PAR-2 is localized to basolateral surfaces, and is not detected on the apical surfaces of somatic cells.
TypeAntibodyRabbit antibody.
PatternThe apical-basal polarity of the PAR protein persists through early gastrulation, although the level of PAR-2 diminishes. Later changes in PAR distribution were not analyzed further.
PictureWBPicture0000007488
RemarkPrevious data: analysis of the PAR proteins has focused primarily on their anterior-posterior localization at the 1-cell stage and their roles in subsequent anterior-posterior polarity. After cell division begins, however, this anterior-posterior asymmetry is reiterated only in the lineage of cells that form the germline. In contrast, some somatic (non-germline) cells show an apical-basal polarity in PAR localization.
ReferenceWBPaper00005115
Antibody_infoWBAntibody00000129
WBAntibody00001590