WormBase Tree Display for Expr_pattern: Expr1820
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Expr1820 | Expression_of | Gene | WBGene00003917 |
---|---|---|---|
Reflects_endogenous_expression_of | WBGene00003917 | ||
Expression_data | Life_stage | WBls:0000005 | |
Anatomy_term | WBbt:0005906 | ||
WBbt:0005994 | |||
WBbt:0006874 | |||
WBbt:0006876 | |||
GO_term | GO:0016323 | ||
Subcellular_localization | By the 4-cell stage, the posterior PAR protein PAR-2 is localized to basolateral surfaces, and is not detected on the apical surfaces of somatic cells. | ||
Type | Antibody | Rabbit antibody. | |
Pattern | The apical-basal polarity of the PAR protein persists through early gastrulation, although the level of PAR-2 diminishes. Later changes in PAR distribution were not analyzed further. | ||
Picture | WBPicture0000007488 | ||
Remark | Previous data: analysis of the PAR proteins has focused primarily on their anterior-posterior localization at the 1-cell stage and their roles in subsequent anterior-posterior polarity. After cell division begins, however, this anterior-posterior asymmetry is reiterated only in the lineage of cells that form the germline. In contrast, some somatic (non-germline) cells show an apical-basal polarity in PAR localization. | ||
Reference | WBPaper00005115 | ||
Antibody_info | WBAntibody00000129 | ||
WBAntibody00001590 |