WormBase Tree Display for Expr_pattern: Expr15979

Expr15979 Expression_of: Gene: WBGene00004796
    Reflects_endogenous_expression_of: WBGene00004796
  Expression_data: Anatomy_term: WBbt:0004761 Certain
      WBbt:0004939 Certain
      WBbt:0004941 Certain
      WBbt:0004943 Certain
      WBbt:0004945 Certain
      WBbt:0006973 Certain
    GO_term: GO:0043025
      GO:0097730
  Type: Genome_editing
    Reporter_gene
  Pattern: SID-2 nucleic acid binding transmembrane protein is specifically enriched in the male-specific ciliated sensory neurons (CEMs, RnBs, and HOB). In all male-specific neurons (CEMs, RnBs, and HOB), the SID-2::mScarlet signal was observed in neuronal cell bodies as a few puncta and was mostly accumulated in ciliary regions. SID-2::mScarlet was also observed in two unidentified cells whose processes converge near the hook structure of the male tail.The SID-2::mScarlet reporter was co-expressed with PKD-2::GFP in male-specific EV-releasing sensory neurons (EVNs), as well as in the intestine in both males and hermaphrodites. SID-2::mScarlet was abundant on the apical surface of the intestine and fully functional in environmental RNAi, consistent with its known role in endocytosis of dsRNA.We also observed SID- 2::mScarlet being environmentally released in the form of ciliary EVs.
  Picture: WBPicture0000015106
    WBPicture0000015107
  Reference: WBPaper00062669
  Variation: WBVar02157710