WormBase Tree Display for Disease_model_annotation: WBDOannot00000601
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| WBDOannot00000601 | Disease_term | DOID:14175 | |
|---|---|---|---|
| Disease_of_species | Homo sapiens | ||
| Modeled_by | Variation | WBVar00091484 | |
| Asserted_gene | WBGene00006922 | ||
| Association_type | is_implicated_in | ||
| Evidence_code | GO_code | IMP | |
| ECO_term | ECO:0007013 | ||
| Experimental_condition | Inducing_agent | ionizing radiation | |
| Modifier_info | Modifier_gene | WBGene00004374 | |
| Modifier_association_type | condition_ameliorated_by | ||
| Genetic_sex | hermaphrodite | ||
| Paper_evidence | WBPaper00036343 | ||
| Disease_model_description | Inactivation of VHL results in accumulation of HIFa protein and is the underlying basis of von HippelLindau disease, a multisystem cancer syndrome; deficiency in RME-2 (via RNAi) completely restored the DNA-damage-induced apoptosis in vhl-1(ok161) mutants. | ||
| Curator_confirmed | WBPerson38202 | ||
| Date_last_updated | 02 Jul 2018 00:00:00 |
