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WormBase Tree Display for Variation: WBVar01473946

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Name Class

WBVar01473946EvidencePaper_evidenceWBPaper00041718
NamePublic_namebx142
Other_name (13)
HGVSgCHROMOSOME_III:g.6635245C>T
Sequence_detailsSMapS_parentSequenceC13B9
Flanking_sequencesaattgttaccctatttcattgctggatacgtaacgtttttaataaattttgaacaactta
Mapping_targetC13B9
Type_of_mutationSubstitutiongaPaper_evidenceWBPaper00041718
SeqStatusSequenced
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00007196
LaboratoryEM
StatusLive
AffectsGeneWBGene00015735
Transcript (13)
InteractorWBInteraction000519220
GeneticsInterpolated_map_positionIII-1.02797
DescriptionPhenotypeWBPhenotype:0000551Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
Remarkpdfr-1 mutants produced an increase in the frequency of high-angle turns (omega turns) compared with wild-type males.Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
WBPhenotype:0001482Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
Remarkpdfr-1 mutant males displayed a decrease in the frequency of body bends (propagation of the sinusoidal wave).Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
WBPhenotype:0001506Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
Remarkpdfr-1 mutants produced an increase in the frequency of reversals compared with wild-type males.Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
WBPhenotype:0001524Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
Remarkpdfr-1 mutants underwent behavioral quiescence in nutritionally high food.Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
WBPhenotype:0002128Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
RemarkMutant males remain on food in the absence of mates. Males had no drive to explore away from food.Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
Rescued_by_transgeneWBTransgene00016274
WBTransgene00016276
EQ_annotationsAnatomy_termWBbt:0005346PATO:0000460Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
WBbt:0004096PATO:0000460Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
WBbt:0007807PATO:0000460Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
WBbt:0006973PATO:0000460Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
Life_stageWBls:0000056PATO:0000460Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
WBPhenotype:0002130Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
WBPhenotype:0004004Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
RemarkMutants were able to successfully mate, although they did not respond as avidly as wild-type males to mate contact.Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
WBPhenotype:0004028Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
Remarkpdfr-1 mutant males displayed slow movement on food as a result of a decrease in the frequency of body bends.Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
Phenotype_not_observedWBPhenotype:0000643Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
Remarkpdfr-1 mutant males were able to travel the scoring distance of the leaving assay plate (3.5-cm radius) at a rate similar to that of wild-type males if the area was covered with food.Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
WBPhenotype:0001072Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
RemarkAlthough pdfr-1 mutant males displayed higher absolute levels of reversals than wild-type males, reversals decreased twofold by 30 min after the last food exposure, as in wild-type males.Paper_evidenceWBPaper00041718
Curator_confirmedWBPerson712
ReferenceWBPaper00041718
MethodSubstitution_allele