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WormBase Tree Display for Variation: WBVar00275485

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WBVar00275485	Evidence	Paper_evidence	WBPaper00001584
	Name	Public_name	zu121
	Sequence_details	SeqStatus	Pending_curation
	Variation_type	Allele
	Origin	Species	Caenorhabditis elegans
		Strain	WBStrain00022473
		Laboratory	JJ
		Status	Live
	Affects	Gene	WBGene00003228
		Interactor	WBInteraction000520745
	Description	Phenotype	WBPhenotype:0000050	Paper_evidence	WBPaper00001584
				Curator_confirmed	WBPerson2021
				Recessive	Paper_evidence	WBPaper00001584
					Curator_confirmed	WBPerson2021
				EQ_annotations	Life_stage	WBls:0000003	PATO:0000460	Paper_evidence	WBPaper00001584
								Curator_confirmed	WBPerson2021
				Maternal
			WBPhenotype:0000052	Person_evidence	WBPerson261
				Curator_confirmed	WBPerson712
				Remark	Maternal effect lethal mutation, which results in four AB granddaughters of the eight cell stage embryo following a pattern of development nearly identical to the posterior blastomere MS.	Person_evidence	WBPerson261
						Curator_confirmed	WBPerson712
			WBPhenotype:0000715	Paper_evidence	WBPaper00001584
				Person_evidence	WBPerson261
				Curator_confirmed	WBPerson2021
					WBPerson712
				Remark	Mutant embryos produce excess muscle cells	Paper_evidence	WBPaper00001584
						Curator_confirmed	WBPerson2021
					Four AB granddaughters of the eight cell stage embryo following a pattern of development nearly identical to the posterior blastomere MS results in embryos which produce excess muscle.	Person_evidence	WBPerson261
						Curator_confirmed	WBPerson712
				Recessive	Paper_evidence	WBPaper00001584
					Curator_confirmed	WBPerson2021
				EQ_annotations	Life_stage	WBls:0000003	PATO:0000460	Paper_evidence	WBPaper00001584
								Curator_confirmed	WBPerson2021
				Maternal
			WBPhenotype:0001635	Paper_evidence	WBPaper00001584
				Person_evidence	WBPerson261
				Curator_confirmed	WBPerson2021
					WBPerson712
				Remark	Mutants have large clusters of excess pharyngeal cells. These clusters are surrounded by a basement membrane and some of them contain grinder-like structures	Paper_evidence	WBPaper00001584
						Curator_confirmed	WBPerson2021
					Four AB granddaughters of the eight cell stage embryo following a pattern of development nearly identical to the posterior blastomere MS results in embryos which produce excess pharynx.	Person_evidence	WBPerson261
						Curator_confirmed	WBPerson712
				Recessive	Paper_evidence	WBPaper00001584
					Curator_confirmed	WBPerson2021
				EQ_annotations	Life_stage	WBls:0000003	PATO:0000460	Paper_evidence	WBPaper00001584
								Curator_confirmed	WBPerson2021
				Maternal
			WBPhenotype:0001637	Paper_evidence	WBPaper00001584
				Curator_confirmed	WBPerson2021
				Remark	mex-1 alleles show a cold-sensitive defect in producing intestinal cells. Embryos that were lacking intestinal cells, contained larger numbers of hypodermal cells instead	Paper_evidence	WBPaper00001584
						Curator_confirmed	WBPerson2021
				Penetrance	Incomplete	72 percent	Paper_evidence	WBPaper00001584
							Curator_confirmed	WBPerson2021
				Recessive	Paper_evidence	WBPaper00001584
					Curator_confirmed	WBPerson2021
				EQ_annotations	Life_stage	WBls:0000003	PATO:0000460	Paper_evidence	WBPaper00001584
								Curator_confirmed	WBPerson2021
				Maternal
				Phenotype_assay	Temperature	16C, 25C	Paper_evidence	WBPaper00001584
							Curator_confirmed	WBPerson2021
		Phenotype_not_observed	WBPhenotype:0001642	Paper_evidence	WBPaper00001584
				Curator_confirmed	WBPerson2021
				Remark	Mutant embryos appear identical to wild-type embryos in terms of size, cleavage rate, and division axes up to the 28-cell stage (data not shown)	Paper_evidence	WBPaper00001584
						Curator_confirmed	WBPerson2021
				Recessive	Paper_evidence	WBPaper00001584
					Curator_confirmed	WBPerson2021
				EQ_annotations	Life_stage	WBls:0000003	PATO:0000460	Paper_evidence	WBPaper00001584
								Curator_confirmed	WBPerson2021
				Maternal
	Reference	WBPaper00001584
	Method	Allele