WormBase Tree Display for Variation: WBVar00275393
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WBVar00275393 | Name | Public_name | ye27 | |||||
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Sequence_details | SeqStatus | Pending_curation | ||||||
Variation_type | Allele | |||||||
Origin | Species | Caenorhabditis elegans | ||||||
Strain | WBStrain00008568 | |||||||
Laboratory | HY | |||||||
Status | Live | |||||||
Affects | Gene | WBGene00000269 | ||||||
Description | Phenotype | WBPhenotype:0001379 | Paper_evidence | WBPaper00034766 | ||||
Curator_confirmed | WBPerson2021 | |||||||
Remark | In contrast to wt, induction of LEC-8::EGFP after exposure to Cry5B toxin was low in bre-4 mutants | Paper_evidence | WBPaper00034766 | |||||
Curator_confirmed | WBPerson2021 | |||||||
WBPhenotype:0001507 | Paper_evidence | WBPaper00034766 | ||||||
Curator_confirmed | WBPerson2021 | |||||||
Remark | When bre mutant worms were fed E. coli expressing Cry5B, they did not exhibit toxic effects and remained alive under the same conditions in which wild-type worms had died. | Paper_evidence | WBPaper00034766 | |||||
Curator_confirmed | WBPerson2021 | |||||||
WBPhenotype:0001524 | Paper_evidence | WBPaper00051118 | ||||||
Curator_confirmed | WBPerson38423 | |||||||
Remark | Lethargus duration increased by 23%; total sleep increased by 34%; Bout duration increased by 6% (Table 2A) | Paper_evidence | WBPaper00051118 | |||||
Curator_confirmed | WBPerson38423 | |||||||
WBPhenotype:0002035 | Paper_evidence | WBPaper00039883 | ||||||
Curator_confirmed | WBPerson9999 | |||||||
Remark | resistant to fruiting body lectin Marasmius oreades agglutinin (MOA, a Galα1,3Gal/GalNAc-specific lectin) | Paper_evidence | WBPaper00039883 | |||||
Curator_confirmed | WBPerson9999 | |||||||
Affected_by | Molecule | WBMol:00007870 | Paper_evidence | WBPaper00039883 | ||||
Curator_confirmed | WBPerson9999 | |||||||
WBPhenotype:0002060 | Paper_evidence | WBPaper00004264 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Produces a brood when grown in the presence of Bt toxin Cry5B. The intestines of mutants fed Bt-produced toxin have intestinal morphology often indistinguishable from that of healthy wild-type intestine not exposed to toxin. Mutants are resistant to Cry5B-induced lethality. Unlike toxin-exposed wild-type animals, toxin-exposed mutants show only a modest reduction in fertility. Similar resistance is observed for animals exposed to E. coli produced Cry5B toxin. Mutants are similarly sensitive to Cry6A. | Paper_evidence | WBPaper00004264 | |||||
Curator_confirmed | WBPerson712 | |||||||
Recessive | Paper_evidence | WBPaper00004264 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Affected_by | Molecule | WBMol:00005329 | Paper_evidence | WBPaper00004264 | ||||
Curator_confirmed | WBPerson712 | |||||||
Phenotype_not_observed | WBPhenotype:0000072 | Paper_evidence | WBPaper00004264 | |||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Animals appear morphologically normal. | Paper_evidence | WBPaper00004264 | |||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0000517 | Paper_evidence | WBPaper00004264 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Animals behave similarly to wild-type. | Paper_evidence | WBPaper00004264 | |||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0000673 | Paper_evidence | WBPaper00004264 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Animals have wild-type brood sizes. | Paper_evidence | WBPaper00004264 | |||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0000676 | Paper_evidence | WBPaper00004264 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Animals develop from embryos to adults at the normal wild-type rate. | Paper_evidence | WBPaper00004264 | |||||
Curator_confirmed | WBPerson712 | |||||||
Reference | WBPaper00039883 | |||||||
WBPaper00004264 | ||||||||
WBPaper00034766 | ||||||||
WBPaper00051118 | ||||||||
Method | Allele |