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WormBase Tree Display for Variation: WBVar00251205

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Name Class

WBVar00251205NamePublic_nametm2303
Other_nameT07G12.11a.1:c.625_838del
CE21166:p.Cys209MetfsTer51
CE45931:p.Cys209MetfsTer51
T07G12.11b.1:c.625_838del
HGVSgCHROMOSOME_IV:g.10559408_10559778del
Sequence_detailsSMapS_parentSequenceT07G12
Flanking_sequencestatgaattattcgaagattcctccaatgacatgaaaccatggtgccacactccgaaccaa
Mapping_targetT07G12
Source_location7CHROMOSOME_IV1055940710559779Inferred_automaticallyNational_Bioresource_Project
Type_of_mutationDeletion
PCR_producttm2303_external
tm2303_internal
SeqStatusSequenced
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00004048
LaboratoryFX
AuthorMitani S
DB_infoDatabaseNational_Bioresource_Projectseq2303
NBP_allele
StatusLive
AffectsGeneWBGene00011601
TranscriptT07G12.11a.1 (11)
T07G12.11b.1 (11)
IsolationMutagenTMP/UV
GeneticsMapIV
DescriptionPhenotypeWBPhenotype:0000052Person_evidenceWBPerson7743
Curator_confirmedWBPerson48
RemarkComment from Dr. A. Dernburg to the National Bioresource Project of Japan: homozygous worms are viable and healthy, but produce many (~70%) inviable progeny.Person_evidenceWBPerson7743
Curator_confirmedWBPerson48
PenetranceIncompletePerson_evidenceWBPerson7743
Curator_confirmedWBPerson48
WBPhenotype:0000062Person_evidenceWBPerson7743
Curator_confirmedWBPerson48
RemarkClassified as lethal OR sterile by the National Bioresource Project of Japan.Person_evidenceWBPerson7743
Curator_confirmedWBPerson48
Laboratory_evidenceFX
WBPhenotype:0000206Person_evidenceWBPerson7743
Curator_confirmedWBPerson48
RemarkComment from Dr. A. Dernburg to the National Bioresource Project of Japan: homozygous worms are viable and healthy, but produce many (~70%) inviable progeny due to missegregation of chromosome I and IV during meiosis.Person_evidenceWBPerson7743
Curator_confirmedWBPerson48
WBPhenotype:0000688Person_evidenceWBPerson7743
Curator_confirmedWBPerson48
RemarkClassified as lethal OR sterile by the National Bioresource Project of Japan.Person_evidenceWBPerson7743
Curator_confirmedWBPerson48
Laboratory_evidenceFX
WBPhenotype:0001175Person_evidenceWBPerson7743
Curator_confirmedWBPerson48
RemarkComment from Dr. A. Dernburg to the National Bioresource Project of Japan: Weak Him phenotype (6.7% males), which is an indirect consequence of autosomal defects during meiosis.Person_evidenceWBPerson7743
Curator_confirmedWBPerson48
ReferenceWBPaper00061173
Remark30975/30976-31346/31347 (371 bp deletion)
This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use.Paper_evidenceWBPaper00041807
Variation stub/paper connection generated from the May 2021 NN VFP dataset.
Created by WBPerson51134 from the NN_VFP_triage_pipeline
MethodNBP_knockout_allele