WormBase Tree Display for Variation: WBVar00248844

WBVar00248844 Evidence: Paper_evidence: WBPaper00032195
  Name: Public_name: su75
  Sequence_details: Mapping_target: C09D1
    Type_of_mutation: Insertion: c Paper_evidence: WBPaper00049445
    SeqStatus: Pending_curation
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: HE
    Status: Live
  Affects: Gene: WBGene00006820
    Interactor: WBInteraction000009110
  Description: Phenotype: WBPhenotype:0000782 Paper_evidence: WBPaper00041265
        Curator_confirmed: WBPerson557
        Remark: Adults have body-wall muscle with disorganized thick filaments. Paper_evidence: WBPaper00041265
            Curator_confirmed: WBPerson557
        Phenotype_assay: Treatment: Animals carried the GFP::MHC A transgene to mark thick filaments. Paper_evidence: WBPaper00041265
              Curator_confirmed: WBPerson557
      WBPhenotype:0001569 Paper_evidence: WBPaper00032195
        Curator_confirmed: WBPerson712
        Remark: MHC A immunostaining revealed a disorganization of thick filaments, including what appear to be abnormal aggregates of myosin or thick filaments, and V-shaped crossing of A-bands rather than the straight lines observed in the wild type muscle. Paper_evidence: WBPaper00032195
            Curator_confirmed: WBPerson712
    Phenotype_not_observed: WBPhenotype:0000640 Paper_evidence: WBPaper00032195
        Curator_confirmed: WBPerson712
  Reference: WBPaper00032195
    WBPaper00049445
    WBPaper00041265
  Method: Insertion_allele